Exercise training reverse autonomic dysfunction and hypertension in rats fed with high-fat diet

Abstract AIMS We evaluated whether exercise training ameliorates cardiovascular autonomic dysfunction in obesity-induced by high-fat diet (HFD) in rats. METHODS Wistar male rats were assigned in normal diet, sedentary (ND-S) and trained (ND-T) and HFD, sedentary (HFD-S) and trained (HFD-T). Blood pressure (BP), heart rate (HR), HR variability (HRV), BP variability (BPV), cardiac baroreflex and cardiac autonomic tonus were assessed. RESULTS HFD-S showed higher bodyweight increase (19.4%) compared to all other groups (HFD-T: 13.2%, ND-S: 14% and ND-T: 12.4%). Relative epididymal, retroperiton...