Dielectric Behavior of Alginate-Based Hydrogel Containing Neomycin-Loaded Lipid Nanovesicles under Influence of Electrical Potentials

Dielectric characterization has been applied as a convenient tool for evaluation of transport and polarization mechanisms in soft materials. In this work, we have explored the study of charge transport mechanisms in alginate hydrogel containing neomycin-loaded liposomes. For comparison, drug release kinetic was evaluated by using UV-Vis spectrophotometry and electrical impedance spectroscopy (EIS) at different external direct current (DC) polarization (100 mV and 1 V). The charge transfer resistance (Rct) was proportional to DC electrical stimulation and inversely to the amount of released neo...