DEVELOPMENT OF AN AUTOMATED METHOD TO PERFORM A QUANTITATIVE STUDY OF PARTICLE SIZE DISTRIBUTION AND THE EFFECT OF A CONDUCTIVE LAYER IN SCANNING ELECTRON MICROSCOPY

The determination of particle size distribution is an important parameter for controlling industrial processes, particularly in the field of pharmaceuticals. It is also an important parameter for characterizing nanoparticles. The best technique for determining particle size distribution is scanning electron microscopy. The process of counting particles is typically performed manually, which requires both more time and a higher standard deviation than automatic methods. This study shows the results of a particle counting procedure that relies on a fully automated method that was found to improv...