DEVELOPMENT AND OPTIMIZATION OF A MICROWAVE-ASSISTED EXTRACTION OF PLUMIERIDE FROM Allamanda cathartica L. FLOWERS

A simple and efficient microwave-assisted extraction process has been developed in order to extract plumieride from Allamanda cathartica flowers. The extracts have been obtained through microwave-assisted extraction (MAE) process with ethanol and ethyl acetate at different time, power and temperatures. Static maceration at room temperature with ethanol and ethyl acetate was obtained in order to compare the efficiency of extraction. HPLC method was validated to quantify plumieride in the extracts. The analyzed parameters: linearity (R2 = 0.999), precision (CV 3.3%), recovery (98%), specificity ...