Changes in energy and motor activity: core symptoms of bipolar mania and depression?

Objective: To evaluate how well symptom rating scales differentiate bipolar disorder (BD) episode types. Methods: One hundred and six patients with BD were followed for 13 years. At each visit, the following clinical scales were administered: Young Mania Rating Scale (YMRS), Hamilton Depression Scale (HAM-D) and Clinical Global Impressions scale for use in bipolar illness (CGI-BP). To perform a comparison between the affective states of BP, three time points in each patient’s follow-up period were chosen for evaluation: the most severe manic episode, the most severe depressive episode, and...