An easy and practical prognostic parameter: tumor–stroma ratio in Luminal, Her2, and triple-negative breast cancers

SUMMARY OBJECTIVE: The stroma surrounding the tumor cells is important in tumor progression and treatment resistance, besides the properties of tumor cells. Studies on the tumor stroma characteristics will contribute to the knowledge for new treatment approaches. METHODS: A total of 363 breast cancer patients were evaluated for the tumor–stroma ratio. The percentage of stroma was visually assessed on hematoxylin–eosin stained slides. The cases of tumor–stroma ratio more than 50% were categorized as tumor–stroma ratio high, and those less than 50% and below were categorized as tumor�...

Texto completo