Algorithm for predicting macular dysfunction based on moment invariants classification of the foveal avascular zone in functional retinal images

Abstract Introduction A new method for segmenting and quantifying the macular area based on morphological alternating sequential filtering (ASF) is proposed. Previous studies show that persons with diabetes present alterations in the foveal avascular zone (FAZ) prior to the appearance of retinopathy. Thus, a proper characterization of FAZ using a method of automatic classification and prediction is a supportive and complementary tool for medical evaluation of the macular region, and may be useful for possible early treatment of eye diseases in persons without diabetic retinopathy. Methods We...