A EVOLUÇÃO DA QUÍMICA MEDICINAL NO BRASIL: AVANÇOS NOS 40 ANOS DA SOCIEDADE BRASILEIRA DE QUÍMICA

Medicinal Chemistry includes the invention, discovery, design, identification, and interpretation of the molecular mechanism of action of biologically active compounds. In addition to the discovery of bioactive molecules, Medicinal Chemistry investigates drug metabolism and the relationships between chemical structure and biological activity. The advances achieved in the 20th century have significantly contributed to the better understanding of pathophysiological processes as well as the development of new, safer and more effective drugs for many diseases. In this article, we review the evolut...