Telomere
Mostrando 1-12 de 907 artigos, teses e dissertações.
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1. Chromosome diversity in Buthidae and Chactidae scorpions from Brazilian fauna: Diploid number and distribution of repetitive DNA sequences
Abstract In this work, we analyzed cytogenetically eight Chactidae and Buthidae, including the localization of repetitive DNA sequences. The chactids possess monocentric chromosomes and the highest diploid numbers (2n=50 in Brotheas amazonicus, 2n=36 in Chactopsis amazonica, 2n=30 in Neochactas sp.) when compared with buthids (2n=10 in Tityus bahiensis, 2n=1
Genetics and Molecular Biology. Publicado em: 2023
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2. Association between leukocyte telomere length and sex by quantile regression analysis
ABSTRACT Introduction: Telomere length (TL) is a biomarker of cellular proliferative history. In healthy individuals, leukocyte TL shortens with age and associates with the lifespan of men and women. However, most of studies had used linear regression models to address the association of the TL attrition, aging and sex. Methods: We evaluated the associatio
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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3. Telomere length: biological marker of cellular vitality, aging, and health-disease process
SUMMARY The aging process occurs due to the decline of vital physiological functions and adaptability of the body, being influenced by genetics and lifestyle. With advances in genetics, biological aging can be calculated by telomere length. Telomeres are regions at the ends of chromosomes that play a role in the maintenance and integrity of DNA. With biologi
Rev. Assoc. Med. Bras.. Publicado em: 2021-02
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4. Familial pulmonary fibrosis: a heterogeneous spectrum of presentations
RESUMO Objetivo: Descrever as características clínicas, funcionais e radiológicas de um grupo de casos índice diagnosticados com fibrose pulmonar familiar (FPF) no Brasil. Métodos: Trinta e cinco pacientes com FPF (18 mulheres; 51,4%), com mediana de idade de 66,0 anos (variação: 35,5-89,3 anos), responderam a um questionário padronizado e foram su
J. bras. pneumol.. Publicado em: 10/06/2019
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5. Immunosenescence: participation of T lymphocytes and myeloid-derived suppressor cells in aging-related immune response changes
RESUMO O envelhecimento saudável está relacionado, pelo menos em parte, com a função adequada do sistema imunológico. Isso porque já foi relatado que, com o envelhecimento, algumas mudanças desse sistema são observadas, como a diminuição da percentagem e do repertório de células T pela involução tímica, acúmulo de células T de memória por i
Einstein (São Paulo). Publicado em: 02/05/2019
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6. Is the telomere length associated with neurocognitive disabilities in HIV-1-infected subjects?
ABSTRACT Objective: We evaluated the association between cognitive deficits and leukocyte telomere length (LTL) in HIV-1-infected individuals. Design: 73 HIV-1-infected patients undergoing neuropsychological evaluation and 91 healthy controls were included in this study. Fifteen HIV-1 positive patients did not have cognitive disorders whereas 26 had asympt
Rev. Inst. Med. trop. S. Paulo. Publicado em: 23/04/2018
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7. Analyzing leukocyte telomere length in bipolar disorder
Rev. Bras. Psiquiatr.. Publicado em: 2017-09
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8. Analyzing leukocyte telomere length in bipolar disorder: Authors’ reply
Rev. Bras. Psiquiatr.. Publicado em: 2017-09
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9. Telomere length and hTERT in mania and subsequent remission
Objective: The findings of telomere length (TL) studies in bipolar disorder (BD) are controversial. The aim of the present study was to detect TL, human telomerase reverse transcriptase (hTERT), and brain derived neurotrophic factor (BDNF) in severe mania and subsequent remission. Methods: Twenty-one medication-free male patients and 20 age and gender matc
Rev. Bras. Psiquiatr.. Publicado em: 06/07/2017
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10. Telomere length correlates with disease severity and inflammation in sickle cell disease
ABSTRACT Background: Telomeres, the ends of linear chromosomes, shorten during mitotic cell division and erosion may be aggravated by inflammation or proliferative and oxidative stress. As the bone marrow is under hyperproliferative pressure in sickle cell disease and several tissues are submitted to chronic inflammation, this study sought to determine the
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-06
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11. Stressed ends: telomere attrition in chronic diseases
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-06
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12. Telomere length analysis in monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia Binet A
Monoclonal B-cell lymphocytosis (MBL) is an asymptomatic clinical entity characterized by the proliferation of monoclonal B cells not meeting the diagnosis criteria for chronic lymphocytic leukemia (CLL). MBL may precede the development of CLL, but the molecular mechanisms responsible for disease progression and evolution are not completely known. Telomeres
Braz J Med Biol Res. Publicado em: 13/04/2017