Tail Suspension Test
Mostrando 1-12 de 18 artigos, teses e dissertações.
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1. Anxiolytic-like and proneurogenic effects of Trichilia catigua ethyl-acetate fraction in mice with cerebral ischemia
Abstract Trichilia catigua A. Juss., Meliaceae, known as "catuaba" in Brazil, has been popularly used as a tonic for fatigue, impotence and memory deficits. Previously, we have demonstrated that T. catigua ethyl-acetate fraction exerted antidepressive-like effects in mice. Affective-like symptoms are also well recognized outcome of cerebral ischemia in clini
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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2. Uliginosin B, a natural phloroglucinol derivative with antidepressant-like activity, increases Na+,K+-ATPase activity in mice cerebral cortex
ABSTRACT Uliginosin B, a phloroglucinol isolated from Hypericum polyanthemum Klotzsch ex Reichardt, Hypericaceae, has antidepressant-like effect in the forced swimming test in rodents and inhibits monoamines neuronal reuptake without binding to their neuronal carriers. Studies showed the involvement of Na+,K+-ATPase brain activity in depressive disorders, as
Rev. bras. farmacogn.. Publicado em: 2016-10
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3. Behavioural alterations are independent of sickness behaviour in chronic experimental Chagas disease
The existence of the nervous form of Chagas disease is a matter of discussion since Carlos Chagas described neurological disorders, learning and behavioural alterations in Trypanosoma cruzi-infected individuals. In most patients, the clinical manifestations of the acute phase, including neurological abnormalities, resolve spontaneously without apparent conse
Mem. Inst. Oswaldo Cruz. Publicado em: 11/12/2015
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4. Evaluation of postpartum behaviour in rats treated with Hypericum perforatum during gestation
Gestational depression is detrimental to the health of the mother and the offspring and contributes to the appearance of depressive and anxiety symptoms during the postnatal period. Traditional antidepressants have undesirable side effects when utilised during gestation, but Hypericum perforatum has been characterised as an efficient and safe antidepressant
Rev. bras. farmacogn.. Publicado em: 2013-10
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5. Animal models as tools to study the pathophysiology of depression
The incidence of depressive illness is high worldwide, and the inadequacy of currently available drug treatments contributes to the significant health burden associated with depression. A basic understanding of the underlying disease processes in depression is lacking; therefore, recreating the disease in animal models is not possible. Popular current models
Rev. Bras. Psiquiatr.. Publicado em: 2013
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6. AVALIAÇÃO DO POTENCIAL EFEITO ANTIDEPRESSIVO DO 2-BFI, LIGANTE IMIDAZOLÍNICO I2, EM CAMUNDONGOS. / EVALUATION OF THE POTENTIAL ANTIDEPRESSANT-LIKE EFFECT OF IMIDAZOLINE I2 2-BFI IN MICE.
A depressão é uma doença psiquiátrica complexa, crônica e incapacitante, que acarreta um alto custo social. Dentre as diversas classes de antidepressivos encontram-se os inibidores da monoamina oxidase-A (MAO-A), que reduzem o metabolismo das monoaminas. Um sítio importante para a regulação da MAO-A é o sítio imidazolínico I2. Recentemente, foi de
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2012
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7. PERFIL FARMACOLÓGICO DO TIPO ANTIDEPRESSIVO DO COMPOSTO 3-(4-FLUOROFENILSELENIL)-2,5 DIFENILSELENOFENO: ENVOLVIMENTO DO SISTEMA SEROTONINÉRGICO / ANTIDEPRESSANT-LIKE PHARMACOLOGICAL PROFILE OF 3-(4- FLUOROPHENYLSELENYL)-2,5-DIPHENYLSELENOPHENE: INVOLVEMENT OF SEROTONERGIC SYSTEM
Depression is a serious, recurrent and incapacitating psychiatric condition with a heavy social burden. The pharmacological approach to this disorder employs therapy with antidepressant drugs, which have side effects and numerous limitations. In view of the promising pharmacological properties of containing-selenium molecules, this study evaluated the effect
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/02/2011
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8. Biological activities of Juglans regia flowers
Antidepressant, anti-inflammatory, antihypoxic and antioxidant activities of methanol extract of Juglans regia L., Juglandaceae, flower were investigated. Antidepressant activity was examined by forced swimming test and tail suspension test in mice. Antihypoxic activity was investigated in haemic and circulatory models. The effects were pronounced in both mo
Revista Brasileira de Farmacognosia. Publicado em: 03/06/2011
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9. EFEITOS AGUDOS DA ASSOCIAÇÃO DE ETANOL E AMINOFILINA EM TESTES COMPORTAMENTAIS E NEUROQUÍMICOS EM CAMUNDONGOS / ACUTE EFFECTS OF ETHANOL AND ASSOCIATION TESTS IN aminophylline behavioral and neurochemical IN MICE
Ethanol effects in central nervous system (CNS) are due to its action in several neurotransmitter systems, changing the existing balance in inhibitory and excitatory pathways. Aminophylline, a methylxanthine with stimulant action, is an adenosine receptor antagonist, and actually used in treatment of asthma and consciousness recovery after long period of ane
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/05/2010
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10. InvestigaÃÃo da aÃÃo central do carvacrol em modelos de ansiedade, depressÃo e convulsÃo em camundongos e possÃveis mecanismos farmacolÃgicos envolvidos. / Investigation of central actions of carvacrol in animal models of anxiety, depression and convulsion in mice and possible pharmacological mechanisms involved.
Carvacrol (5-Isopropyl-2-methylphenol) is a monoterpenic phenol present in the essencial oil of many plants. It is the major component of the essential oil fraction of oregano and thyme. This work presents the behavioral effects of carvacrol in animal models of anxiety, depression, sedation and convulsion, such as, elevated plus maze (EPM), open field, rota
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/01/2010
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11. EFEITOS AGUDOS DA ASSOCIAÇÃO DE ETANOL E MINOFILINA EM TESTES COMPORTAMENTAIS E NEUROQUÍMICOS EM CAMUNDONGOS / ACUTE EFFECTS OF THE ASSOCIATION OF ETHANOL ON TESTING AND AMINOPHYLLINE BEHAVIORAL AND NEUROCHEMICAL IN MICE
Ethanol effects in central nervous system (CNS) are due to its action in several neurotransmitter systems, changing the existing balance in inhibitory and excitatory pathways. Aminophylline, a methylxanthine with stimulant action, is an adenosine receptor antagonist, and actually used in treatment of asthma and consciousness recovery after long period of ane
Publicado em: 2010
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12. InvestigaÃÃo dos efeitos centrais e gastroprotetores do isopulegol em camundongos / Evaluation of the central nervous system and gastroprotective effects of isopulegol in mice.
Isopulegol is a monoterpene alcohol present in the essential oils of various plants, and has been used in the manufacture of fragrances with blossom compositions. In order to investigate its effects on animal models of CNS actions, isopulegol was administered to male Swiss mice at single doses of 25 and 50 mg/kg 30 (i.p.) or 60 min (p.o.) before the experime
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/08/2009