T Lymphocyte Subsets
Mostrando 1-12 de 249 artigos, teses e dissertações.
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1. Effects of astragaloside IV on inflammation and immunity in rats with experimental periodontitis
Abstract: This study aimed to investigate the effects of astragaloside IV (AsIV) on inflammation and immunity in rats with experimental periodontitis. Periodontitis was established in 48 Wistar rats, which were then randomly divided into model and 10, 20 and 40 mg/kg AsIV groups, with 12 rats in each group. The latter 3 groups were treated with AsIV at doses
Braz. oral res.. Publicado em: 25/04/2019
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2. Altered peripheral lymphocyte subsets in untreated systemic lupus erythematosus patients with infections
The leading cause of death in systemic lupus erythematosus (SLE) patients is infection. The objective of this study was to evaluate the distribution of lymphocyte subsets in untreated SLE patients with infections. This was a cross-sectional study. Data from January 2017 to May 2018 were collected. Flow cytometry was used to measure the peripheral lymphocyte
Braz J Med Biol Res. Publicado em: 15/04/2019
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3. Increased peripheral blood TCD4+ counts and serum SP-D levels in patients with chronic paracoccidioidomycosis, during and after antifungal therapy
BACKGROUND The main clinical forms of paracoccidioidomycosis (PCM) are the acute/subacute form (AF) and the chronic form (CF), and they both display considerable clinical variability. The immune responses of PCM patients, during and after treatment, remain neglected, mainly in the case of CF patients, due to the high prevalence of pulmonary sequelae. OBJEC
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-11
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4. Roles of monocyte chemotactic protein 1 and nuclear factor-κB in immune response to spinal tuberculosis in a New Zealand white rabbit model
This study aimed to explore the roles of monocyte chemotactic protein 1 (MCP-1) and nuclear factor kappa B (NF-κB) in immune response to spinal tuberculosis in a New Zealand white rabbit model. Forty-eight New Zealand white rabbits were collected and divided into four groups: experimental group (n=30, spinal tuberculosis model was established), the sham gro
Braz J Med Biol Res. Publicado em: 20/02/2017
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5. Cytokine profile and lymphocyte subsets in type 2 diabetes
Type 2 diabetes mellitus (T2D) is a metabolic disease with inflammation as an important pathogenic background. However, the pattern of immune cell subsets and the cytokine profile associated with development of T2D are unclear. The objective of this study was to evaluate different components of the immune system in T2D patients' peripheral blood by quantifyi
Braz J Med Biol Res. Publicado em: 18/03/2016
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6. T-cell receptor Vβ repertoire of CD8+ T-lymphocyte subpopulations in cutaneous leishmaniasis patients from the state of Rio de Janeiro, Brazil
In human cutaneous leishmaniasis (CL), the immune response is mainly mediated by T-cells. The role of CD8+ T-lymphocytes, which are related to healing or deleterious functions, in affecting clinical outcome is controversial. The aim of this study was to evaluate T-cell receptor diversity in late-differentiated effector (LDE) and memory CD8+ T-cell subsets in
Mem. Inst. Oswaldo Cruz. Publicado em: 24/06/2015
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7. Lymphocyte subsets in human immunodeficiency virus-unexposed Brazilian individuals from birth to adulthood
Ethnic origin, genetics, gender and environmental factors have been shown to influence some immunologic indices, so that development of reference values for populations of different backgrounds may be necessary. We have determined the distribution of lymphocyte subsets in healthy Brazilian individuals from birth to adulthood. Lymphocyte subsets were determin
Mem. Inst. Oswaldo Cruz. Publicado em: 21/11/2014
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8. Perfil de risco imunológico e resposta humoral ao citomegalovírus e associação com o estado cognitivo funcional em idosos
Introduction: The immune risk phenotype (IRP), as shown by increased CD8+ and low CD4+ T cell counts, and cognitive impairment have been associated with increased morbidity and mortality in very old subjects. Recent evidence suggests that persistent viral infections of the herpesviridae family such as cytomegalovirus (CMV) are likely to be involved with thes
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/08/2012
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9. Imunorregulação central e periférica em pacientes com Síndrome de Down e autoimunidade / Central and peripheral immunoregulation in patients with Down syndrome and autoimmunity
Introdução: A Síndrome de Down (SD) é uma doença genética de alta prevalência, com várias alterações imunológicas decorrentes da disfunção tímica associada à doença. Neste estudo, avaliou-se a associação entre presença de autoimunidade e disfunção do timo em pacientes com SD. Métodos: Foram avaliados 22 pacientes com SD (11 com autoimun
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/11/2011
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10. Evaluation of lymphocyte levels in a random sample of 218 elderly individuals from São Paulo city
BACKGROUND: Age-associated changes in the immune system cause decreased protection after vaccination and increased rates of infections and tumor development. METHODS: Lymphocyte percentages were compared by gender and age to establish differences between subtypes. Three mL blood samples were obtained from 218 randomly selected individuals (60-101 years old)
Revista Brasileira de Hematologia e Hemoterapia. Publicado em: 2011-10
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11. Caracterização fenotípica e funcional de linfócitos T de memória de indivíduos infectados pelo HIV reativos a epitopos T CD4+ derivados de sequências do consenso B do HIV-1 / Phenotypic and functional characterization of memory T lymphocytes from HIV infected individuals reactive to CD4-T epitopes derived from sequences of the HIV-1 B consensus
The persistence of functional memory T cell is important to ensure a protective immunity to Human Immunodeficiency Virus (HIV) infection. Memory T cells have been subdivided into central memory (TCM), effector memory (TEM) and highly differentiated effector memory (TEMRA) based on the expression of surface molecules such as CCR7 and CD45RA, and the ability t
Publicado em: 2010
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12. Lymphocyte subpopulations during cytomegalovirus disease in renal transplant recipients
We have determined the number of circulating T, B and natural killer cells in renal transplant recipients in order to detect changes during cytomegalovirus (CMV) infections. Serial blood samples were taken from 61 patients on standard triple immunosuppression therapy (cyclosporin A, azathioprine and prednisone). Using two-color flow cytometry analysis, the a
Publicado em: 2010