Systemic Sclerosis
Mostrando 13-24 de 311 artigos, teses e dissertações.
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13. Ventilation distribution as a contributor to the functional exercise capacity in patients with systemic sclerosis-associated interstitial lung disease without pulmonary hypertension
Phenotypic differences have been described between patients with systemic sclerosis (SSc)-associated interstitial lung disease (ILD) and SSc-associated pulmonary hypertension, including performance differences in the 6-min walk test (6MWT). Moreover, the correlations between the 6MWT and traditional pulmonary function tests (PFTs) are weak, indicating the ne
Braz J Med Biol Res. Publicado em: 29/07/2019
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14. Position article and guidelines 2018 recommendations of the Brazilian Society of Rheumatology for the indication, interpretation and performance of nailfold capillaroscopy
Abstract Nailfold capillaroscopy (NFC) is a reproducible, simple, low-cost, and safe imaging technique used for morphological analysis of nail bed capillaries. It is considered to be extremely useful for the investigation of Raynaud's phenomenon and for the early diagnosis of systemic sclerosis (SSc). The capillaroscopic pattern typically associated with SSc
Adv. rheumatol.. Publicado em: 29/07/2019
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15. Endothelial lesion and complement activation in patients with Scleroderma Renal Crisis
Resumo Nas revisões de biópsias renais, a crise renal esclerodérmica (CRE) é caracterizada por lesões endoteliais vasculares, depósitos de C4d em vasos peritubulares e lesões agudas e crônicas que coexistem na mesma biópsia. Os sinais clínicos de microangiopatia trombótica (MAT) são descritos na esclerose sistêmica (ES); no entanto, não foram r
J. Bras. Nefrol.. Publicado em: 25/02/2019
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16. Alterações auditivas na esclerose sistêmica
RESUMO Objetivo Descrever as queixas e alterações auditivas em indivíduos com esclerose sistêmica (ES), bem como verificar a evolução do quadro audiológico. Método Trata-se de estudo seccional, com uma fase prospectiva, realizado no período de 2012 e 2015, com pacientes com diagnóstico médico de ES. Foram coletados dados sociodemográficos, an
CoDAS. Publicado em: 21/02/2019
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17. Association of amyloidosis cutis dyschromica and familial Mediterranean fever
Abstract: Amyloidosis cutis dyschromica is a rare type of primary cutaneous amyloidosis characterized by reticulate hyper-pigmentation with discrete hypopigmented macules. Up to date, about 50 cases of amyloidosis cutis dyschromica have been reported and the majority are familial cases of Asian ethnicity. Various diseases, particularly autoimmune diseases su
An. Bras. Dermatol.. Publicado em: 2017
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18. Tanshinone IIA attenuates interleukin-17A-induced systemic sclerosis patient-derived dermal vascular smooth muscle cell activation via inhibition of the extracellular signal-regulated kinase signaling pathway
OBJECTIVE: Salvia miltiorrhiza has long been used to treat systemic sclerosis. Tanshinone IIA, one of the phytochemicals derived from the roots of Salvia miltiorrhiza, exhibits multiple biological activities. The present study aimed to investigate whether tanshinone IIA has an effect on the interleukin-17A-induced functional activation of systemic sclerosis
Clinics. Publicado em: 2015-04
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19. Lower limb muscle strength is associated with functional performance and quality of life in patients with systemic sclerosis
Background: Complaints of peripheral muscle weakness are quite common in patients with systemic sclerosis (SSc). It is likely that the muscle impairments may reduce the patients' exercise performance, which in turn may decrease their functional capacity and exert a direct impact on their quality of life. Objectives: To assess the peripheral and respiratory
Braz. J. Phys. Ther.. Publicado em: 13/03/2015
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20. Localized scleroderma: clinical spectrum and therapeutic update
Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents be
An. Bras. Dermatol.. Publicado em: 2015-02
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21. Alterações auditivas e vestibulares na Esclerose Sistêmica: revisão de literatura
Objetivo:Descrever a prevalência das alterações auditivas e vestibulares em indivíduos com Esclerose Sistêmica (ES) e as hipóteses elencadas para explicar essas alterações.Estratégia de pesquisa:Revisão sistemática, sem meta-análise, a partir das bases de dados PubMed, LILACS, Isi Web of Science, SciELO e SCOPUS, utilizando a combinação das pal
CoDAS. Publicado em: 2014-10
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22. Assessment of light touch sensation in the hands of systemic sclerosis patients
INTRODUCTION: Systemic sclerosis is a relatively rare connective tissue disorder characterized by severe and progressive fibrosis of the skin. Due to the current lack of available information on this subject, the aim of the present study was to assess light touch sensations in the hands of patients with systemic sclerosis. METHODS: We completed a cross-sec
Clinics. Publicado em: 2014-09
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23. Tradução, adaptação cultural e validação para a língua portuguesa (Brasil) do Systemic Sclerosis Questionnaire (SySQ)
Introdução: A esclerose sistêmica (ES) é uma doença multissistêmica, autoimune, caracterizada por disfunção fibroblástica e vasculopatia, causando grande impacto na qualidade de vida (QV). Esta é mensurada por instrumentos ou questionários, geralmente formulados em outros idiomas e inseridos em contextos culturais distintos. Objetivo: Traduzi
Rev. Bras. Reumatol.. Publicado em: 2014-04
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24. Angiotensin II type 1 and 2 receptors and lymphatic vessels modulate lung remodeling and fibrosis in systemic sclerosis and idiopathic pulmonary fibrosis
OBJECTIVE: To validate the importance of the angiotensin II receptor isotypes and the lymphatic vessels in systemic sclerosis and idiopathic pulmonary fibrosis. METHODS: We examined angiotensin II type 1 and 2 receptors and lymphatic vessels in the pulmonary tissues obtained from open lung biopsies of 30 patients with systemic sclerosis and 28 patients wi
Clinics. Publicado em: 2014-01