Synaptic Membrane
Mostrando 1-12 de 747 artigos, teses e dissertações.
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1. Gene variants and serum levels of synaptic vesicle and presynaptic plasma membrane proteins in alcohol dependence and their relationship with impulsivity and temperament
ABSTRACT Background: Exocytosis-related gene variants have been suggested to be associated with externalizing behaviors. Objective: This study aimed to examine VAMP2 26 bp Ins\Del, synaptotagmin XI (Syt11) rs3820594 and 33-bp promoter, Syntaxin 1A (Syn-1A) rs1569061 and SNAP-25 rs1051312 and rs3746544 polymorphisms, their serum levels and their relationshi
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2021-04
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2. Deformation of Mitochondrial Cristae in Human Neural Progenitor Cells Exposed to Valproic Acid
ABSTRACT Neural development represents a dynamic process where mitochondrial integrity is decisive for neuronal activity. Structural changes in these organelles may be related to neurological disorders. Valproic acid (VPA) is an anticonvulsive drug commonly used for epilepsy treatment and its use is associated to increased risk of neuropsychiatric disorders.
An. Acad. Bras. Ciênc.. Publicado em: 23/04/2018
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3. Simvastatin treatment reduces the cholesterol content of membrane/lipid rafts, implicating the N -methyl-D-aspartate receptor in anxiety: a literature review
ABSTRACT Membrane/lipid rafts (MLRs) are plasmalemmal microdomains that are essential for neuronal signaling and synaptic development/stabilization. Inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase (statins) can disable the N-methyl-D-aspartate (NMDA) receptor through disruption of MLRs and, in turn, decrease NMDA-mediated anxiety. This hypothes
Braz. J. Pharm. Sci.. Publicado em: 20/04/2017
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4. Exposure to 50 Hz electromagnetic field changes the efficiency of the scorpion alpha toxin
AbstractBackground Extremely low-frequency (50 Hz) electromagnetic field (ELF-EMF) is produced by electric power transmission lines and electronic devices of everyday use. Some phenomena are proposed as “first effects” of ELF-EMF: the discrete changes in the membrane potential and the increase of the calcium channel activity as well as the intracellular
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 20/10/2015
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5. Effects of nitric oxide on magnocellular neurons of the supraoptic nucleus involve multiple mechanisms
Physiological evidence indicates that the supraoptic nucleus (SON) is an important region for integrating information related to homeostasis of body fluids. Located bilaterally to the optic chiasm, this nucleus is composed of magnocellular neurosecretory cells (MNCs) responsible for the synthesis and release of vasopressin and oxytocin to the neurohypophysis
Braz J Med Biol Res. Publicado em: 2014-02
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6. Relationships between dendritic morphology, spatial distribution and firing patterns in rat layer 1 neurons
The cortical layer 1 contains mainly small interneurons, which have traditionally been classified according to their axonal morphology. The dendritic morphology of these cells, however, has received little attention and remains ill defined. Very little is known about how the dendritic morphology and spatial distribution of these cells may relate to functiona
Braz J Med Biol Res. Publicado em: 2012-12
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7. The sodium pump controls the frequency of action-potential-induced calcium oscillations
Calcium plays a significant role in a number of cellular processes, like muscle contraction, gene expression, synaptic plasticity, signal transduction, but the significance of calcium oscillations (CaOs) is not yet completely understood in most of the cell types. It is a widely accepted fact that CaOs are a frequency encoded signal that allows a cell to use
Comput. Appl. Math.. Publicado em: 2012
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8. In vivo and in vitro effect of imipramine and fluoxetine on Na+, K+-ATPase activity in synaptic plasma membranes from the cerebral cortex of rats
The effects of in vivo chronic treatment and in vitro addition of imipramine, a tricyclic antidepressant, or fluoxetine, a selective serotonin reuptake inhibitor, on the cortical membrane-bound Na+,K+- ATPase activity were studied. Adult Wistar rats received daily intraperitoneal injections of 10 mg/kg of imipramine or fluoxetine for 14 days. Twelve hours af
Publicado em: 2010
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9. Expressão gênica e protéica do canal de cálcio do tipo L e seu envolvimento com o mecanismo de secreção de insulina em ilhotas de langerhans de ratos submetidos à restrição protéica e suplementados com leucina / Gene and protein expression of L type calcium channel and your involvement in the mechanism of insulin secretion in islets of Langerhans of rats submitted to protein restriction and supplementation with leucine
Voltage-dependent calcium channels (CaV) are plasma membrane proteins that lead calcium, and are activated by depolarization of the same by promoting the influx of this ion, which serves as an intracellular second messenger, turning electrical signals into chemical. This process controls several intracellular events such as exocytosis, endocytosis, muscle co
Publicado em: 2010
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10. Synaptic vesicle pool size, release probability and synaptic depression are sensitive to Ca2+ buffering capacity in the developing rat calyx of Held
The calyx of Held, a specialized synaptic terminal in the medial nucleus of the trapezoid body, undergoes a series of changes during postnatal development that prepares this synapse for reliable high frequency firing. These changes reduce short-term synaptic depression during tetanic stimulation and thereby prevent action potential failures during a stimulus
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-01
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11. Efeitos da administração crônica de prolina no conteúdo lipídico de estruturas cerebrais de ratos
Neste trabalho foi investigado o efeito da administração crônica de prolina sobre o conteúdo total de gangliosídios, fosfolipídios e de colesterol, assim como, sobre o perfil de gangliosídios no córtex, no hipocampo, no hipotálamo e no cerebelo de ratos. Também, foi avaliado o conteúdo e o perfil de gangliosídios nas frações solúvel e resisten
Publicado em: 2008
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12. Estudo das atividades neurotoxica e miotoxica de uma fosfolipase A2 basica isolada do veneno total Bothrops marajoensis / Study of neurotoxic and myotoxic activities of a phospholipase A2 isolated from the Bothrops marajoensis venom
In the present work, the neuromuscular effects of the toxin Bmaj-9 isolated from the venom of Bothrops marajoensis in the laboratory of chemistry of proteins at Unicamp were studied. This toxin was assayed in biventer cervicis preparations of little chicken, phrenic diaphragm nerve of mice and in gastrocnemius muscles of mice. In birds preparation, Bmaj-9 ca
Publicado em: 2008