Synapses
Mostrando 1-12 de 915 artigos, teses e dissertações.
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1. Galvanic vestibular stimulation and its applications: a systematic review,
Abstract Objective: Galvanic vestibular stimulation has been evaluated in the context of vestibular rehabilitation. The objective was to identify evidence in the scientific literature about the clinical applications of galvanic vestibular stimulation. Methods: In this systematic review, the articles describing the applications of galvanic vestibular stimul
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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2. Effects of intra-dentate gyrus microinjection of myokine irisin on long-term potentiation in male rats
RESUMO A indução de potenciação de longo prazo (LTP) aumenta a capacidade de armazenamento das sinapses no giro denteado (DG) do hipocampo. A irisina é uma miocina gerada a partir do FNDC5 (um precursor genético) durante o exercício. Embora a administração intra-Cornu Ammonis1 de irisina fortaleça a LTP em camundongos com doença de Alzheimer, os e
Arq. Neuro-Psiquiatr.. Publicado em: 10/01/2020
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3. Stem-cell therapy for hearing loss: are we there yet?
Resumo Introdução: Nos mamíferos, as células ciliadas e os neurônios auditivos não apresentam capacidade regenerativa. Assim, os danos a esses tipos celulares são permanentes e levam à perda auditiva. Contudo, como não há tratamento que restabeleça a função auditiva, as terapias regenerativas utilizando células-tronco representam uma alternati
Braz. j. otorhinolaryngol.. Publicado em: 29/08/2019
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4. New frontiers in the study of memory mechanisms
We review recent work on three major lines of memory research: a) the possible role of the protein kinase M-zeta (PKMzeta) in memory persistence; b) the processes of “synaptic tagging and capture” in memory formation; c) the modulation of extinction learning, widely used in the psychotherapy of fear memories under the name of “exposure therapy”. PKMz
Rev. Bras. Psiquiatr.. Publicado em: 2013-06
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5. Padrão da atividade locomotora e expressão de EAAC1 e GLT1 no córtex pré-frontal e entorrinal de ratos criados em isolamento a partir do desmame / Pattern of locomotor activity and expression of EAAC1 and GLT1 in prefrontal and entorhinal cortex of rats reared in isolation from weaning
Isolation rearing of rats from weaning has been used as an experimental model of psychiatric disorders like schizophrenia. It has been demonstrated that isolation induces morphological, behavioral (like hyperactivity in a novel environment) and neurochemical changes similar to those reported for humans with schizophrenia. Evidence suggest that glutamatergic
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/07/2012
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6. Estudo do mecanismo de ação da atividade acaricida de Calea serrata (Asteraceae) em Rhipicephalus (Boophilus) microplus e da sua toxicidade em roedores
It has been demonstrated that the n-hexane extract of Calea serrata had acaricidal activity against larvae of R. microplus and R. sanguineus. Acetylcholinesterase (AChE), an enzyme that hydrolyses acetylcholine at cholinergic synapses, is a target for pesticides and its inhibition by organophosphates leads to paralysis and death of arthropods. Extensive uses
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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7. Estudo dos grânulos de lipofucsina e das sinapses do córtex temporal durante o envelhecimento / Study of lipofuscin granules and synapses in the temporal cortex during aging.
Alterações morfológicas e funcionais ocorrem durante o envelhecimento, período da vida com maior incidência de doenças neurodegenerativas. No presente trabalho acompanhou-se a evolução dos grânulos de lipofucsina durante o envelhecimento para investigar alterações sinápticas, assim como proteínas associadas com doenças neurodegenerativas (alfa-
Publicado em: 2011
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8. Long-term potentiation and long-term depression: a clinical perspective
Long-term potentiation and long-term depression are enduring changes in synaptic strength, induced by specific patterns of synaptic activity, that have received much attention as cellular models of information storage in the central nervous system. Work in a number of brain regions, from the spinal cord to the cerebral cortex, and in many animal species, ran
Clinics. Publicado em: 2011
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9. Estudos de modelagem molecular e relação estrutura-atividade da acetilcolinesterase e inibidores em Mal de Alzheimer / Molecular modeling studies and structure-activity relationships of acetylcholinesterase inhibitors in Alzheimers disease.
Alzheimers disease is the leading cause of dementia in the elderly. The progression of symptoms is associated with structural changes in cholinergic synapses in specific brain regions and consequentely to decrease the potential of cholinergic neurotransmission. Thus, the increased capacity of cholinergic neurotransmission is the fundamental mechanism of the
Publicado em: 2011
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10. Papel dos receptores B1 e B2 de bradicinina e de captopril nas interações célula hospedeira-Trypanosoma cruzi
The infection of monocytes by Trypanosoma cruzi tripomastigotes is a crucial step for the development of Chagas disease immune response. Infection by T. cruzi has demonstrated to be an active process, involving diverse cellular components and different cell types. Previous studies of the interaction tissue-culture derived trypomastigotes (TCT) between cardio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/08/2010
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11. An examination of synaptic proteins following chronic haloperidol in a rat model of tardive dyskinesia
Tardive dyskinesia (TD) is a late-onset side effect mainly affecting the orofacial region of patients treated chronically with classic antipsychotic drugs such as haloperidol (HAL). The causes of TD remain unknown. We hypothesized that faulty synaptic re-organization might be related to TD-like syndromes and used the vacuous chewing movements (VCM) model in
Psychology & Neuroscience. Publicado em: 2010-12
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12. A simple model for circadian timing by mammals
Circadian timing is structured in such a way as to receive information from the external and internal environments, and its function is the timing organization of the physiological and behavioral processes in a circadian pattern. In mammals, the circadian timing system consists of a group of structures, which includes the suprachiasmatic nucleus (SCN), the i
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-01