Symporters
Mostrando 1-12 de 30 artigos, teses e dissertações.
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1. Metilação do gene simportador sódio-iodo (NIS) em tumores de tireóide / Methylation of sodium iodide symporter (NIS) gene in thyroid tumors
O iodo é transportado para a célula tireoideana através do simportador sódio-iodo (NIS). Estudo anterior de nosso grupo mostrou que a expressão do RNAm de NIS estava reduzida nos tecidos tumorais (T) tireoideanos quando comparada à dos tecidos não tumorais (NT) adjacentes. A metilação de ilhas CpG localizadas em promotores é um dos mecanismos epige
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/12/2011
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2. Expressão do simportador sódio-iodo (NIS) nos tumores tireoidianos benignos e malignos através de estudo imunohistoquímico e da quantificação do RNA mensageiro / Expression of the sodium iodide symporter (NIS) in benign and malignant thyroid tumors using immunohistochemistry and mesenger RNA quantification
The iodide uptake by epithelial thyroid cells requires the expression of sodium iodide symporter (NIS), a transmembrane glycoprotein of 643 amino acids. NIS is located at basolateral plasma membrane of the thyroid follicular cells and couples the transport of iodide and sodium to this cells. NIS gene was cloned in 1996, being the first step of investigation
Publicado em: 2007
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3. His-65 in the proton–sucrose symporter is an essential amino acid whose modification with site-directed mutagenesis increases transport activity
The proton–sucrose symporter that mediates phloem loading is a key component of assimilate partitioning in many higher plants. Previous biochemical investigations showed that a diethyl pyrocarbonate-sensitive histidine residue is at or near the substrate-binding site of the symporter. Among the proton–sucrose symporters cloned to date, only the histidine
The National Academy of Sciences.
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4. A Chloroplast Phosphate Transporter, PHT2;1, Influences Allocation of Phosphate within the Plant and Phosphate-Starvation Responses
The uptake and distribution of Pi in plants requires multiple Pi transport systems that must function in concert to maintain homeostasis throughout growth and development. The Pi transporter PHT2;1 of Arabidopsis shares similarity with members of the Pi transporter family, which includes Na+/Pi symporters of fungal and animal origin and H+/Pi symporters of b
American Society of Plant Biologists.
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5. Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters.
Cell surface receptors for gibbon ape leukemia virus (Glvr-1) and murine amphotropic retrovirus (Ram-1) are distinct but related proteins having multiple membrane-spanning regions. Distant homology with a putative phosphate permease of Neurospora crassa suggested that these receptors might serve transport functions. By expression in Xenopus laevis oocytes an
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6. Relationship between the Na+/H+ antiporter and Na+/substrate symport in Bacillus alcalophilus.
The Na+/H+ antiporter of the obligate alkalophile Bacillus alcalophilus facilitates growth at alkaline pH and precludes growth below pH 8.5. Thus, nonalkalophilic mutant strains do not exhibit Na+/H+ antiport activity and, interestingly, such strains concomitantly lose the ability to catalyze Na+-dependent accumulation of alpha-aminoisobutyrate [Krulwich, T.
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7. Characterization of Source- and Sink-Specific Sucrose/H+ Symporters from Carrot
To understand how sucrose (Suc) is transported from source leaves to developing tap roots of carrot (Daucus carota L.), we cloned two cDNAs (DcSUT1 and DcSUT2) for proteins with homologies to plant Suc/H+ symporters. The deduced polypeptide sequences are 52% identical and have 12 predicted membrane-spanning domains each. Transport activities were confi
American Society of Plant Physiologists.
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8. Competition for glucose between the yeasts Saccharomyces cerevisiae and Candida utilis.
The competition between the yeasts Saccharomyces cerevisiae CBS 8066 and Candida utilis CBS 621 for glucose was studied in sugar-limited chemostat cultures. Under aerobic conditions, C. utilis always successfully completed against S. cerevisiae. Only under anaerobic conditions did S. cerevisiae become the dominant species. The rationale behind these observat
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9. Continuous-culture study of the regulation of glucose and fructose transport in Kluyveromyces marxianus CBS 6556.
Regulation of transport of D-glucose and D-fructose was studied in Kluyveromyces marxianus grown in continuous culture. Both substrates could be transported by at least two different transport systems, low-affinity transport and high-affinity proton-sugar symport. The low-affinity transporter, specific for both glucose and fructose, was constitutively presen
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10. Efflux-mediated multidrug resistance in Bacillus subtilis: similarities and dissimilarities with the mammalian system.
Bacillus subtilis cells selected for their resistance to rhodamine 6G demonstrated a multidrug-resistance (MDR) phenotype resembling that of mammalian MDR cells. Like MDR in mammalian cells, MDR in bacteria was mediated by the efflux of the drugs from the cells. The bacterial multidrug efflux system transported similar drugs and was sensitive to similar inhi
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11. Repressible cation-phosphate symporters in Neurospora crassa.
The filamentous fungus Neurospora crassa possesses two nonhomologous high-affinity phosphate permeases, PHO-4 and PHO-5. We have isolated separate null mutants of these permeases, allowing us to study the remaining active transporter in vivo in terms of phosphate uptake and sensitivity to inhibitors. The specificity for the cotransported cation differs for P
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12. A family of retroviruses that utilize related phosphate transporters for cell entry.
The amphotropic murine retrovirus receptor Ram-1 shows significant sequence similarity to the gibbon ape leukemia virus (GALV) receptor Glvr-1, and both of these cell surface virus receptors normally function as sodium-dependent phosphate symporters. However, Ram-1 from humans or rats does not serve as a receptor for GALV, and Glvr-1 from humans does not ser