Sympathetic Nervous System Drug Effects
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. Effect of the systemic administration of methylprednisolone on the lungs of brain-dead donor rats undergoing pulmonary transplantation
OBJECTIVE: Most lung transplants are obtained from brain-dead donors. The physiopathology of brain death involves hemodynamics, the sympathetic nervous system, and inflammatory mechanisms. Administering methylprednisolone 60 min after inducing brain death in rats has been shown to modulate pulmonary inflammatory activity. Our objective was to evaluate the e
Clinics. Publicado em: 2014-02
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2. Effect of carotid and aortic baroreceptors on cardiopulmonary reflex: the role of autonomic function
We determined the sympathetic and parasympathetic control of heart rate (HR) and the sensitivity of the cardiopulmonary receptors after selective carotid and aortic denervation. We also investigated the participation of the autonomic nervous system in the Bezold-Jarish reflex after selective removal of aortic and carotid baroreceptors. Male Wistar rats (220-
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-07
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3. Estudo dos mecanismos envolvidos na redução da sensibilidade à insulina decorrente da restrição crônica de sal: o sistema nervoso simpático e a via 1-arginina - óxido nítrico / Study of the mechanisms of the lower insulin sensitivity due to chronic salt restriction: the sympathetic nervous system and the l-arginine - nitric oxide pathway
A restrição crônica de sal na dieta tem sido recomendada como medida não medicamentosa do tratamento da hipertensão arterial sistêmica. Entre os efeitos observados desta medida terapêutica tem sido descrita uma redução dos valores da pressão arterial (PA), tanto em indivíduos normotensos e pacientes hipertensos, assim como em animais de laboratór
Publicado em: 2003
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4. Use of alpha 2 adrenoreceptor agonists and antagonists in the functional assessment of the sympathetic nervous system.
We studied the effects of clonidine, an alpha 2-adrenoreceptor agonist, and yohimbine, an alpha 2-adrenoreceptor antagonist, on blood pressure, heart rate, and plasma catecholamines in 12 patients with autonomic dysfunction. Clonidine (0.1 mg, orally) lowered blood pressure 18 +/- 3 torr in six subjects and raised it 5 +/- 1 torr in six. The change in blood
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5. The effects and interactions of angiotensin and vasopressin on the heart of unanaesthetized sheep.
The effects of infusions of angiotensin and vasopressin, in stepwise concentrations, on the cardiac baroreflex and on cardiac output were studied in seven adult unanaesthetized sheep and compared with those obtained with infusions of phenylephrine. Six animals were treated with the beta-adrenoceptor blocking drug, propranolol (in order to inhibit the effects
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6. Inhibition of cardiac sympathetic nerve activity during intravenous administration of lidocaine.
The antiarrhythmic action of lidocaine has been attributed solely to its direct electrophysiological effects on the heart. However, lidocaine is particularly effective in treating ventricular arrhythmias associated with increased sympathetic activity, e.g., in myocardial infarction and digitalis toxicity. We tested the hypothesis that lidocaine administered
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7. Mechanisms of reflex vasodilation: assessment of the role of neural reuptake of norepinephrine and release of histamine
The mechanisms of reflex vasodilation were studied in an innervated canine hindlimb preparation which was perfused at a constant rate. Reflex vasodilation was produced by suddenly increasing the pressure in the trunk by the intravenous injection of norepinephrine, with consequent stimulation of the baroreceptors. When the basal vasoconstrictor tone exerted b