Sympathetic Hyperactivity
Mostrando 13-24 de 29 artigos, teses e dissertações.
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13. Efeito do uso de carvedilol no sistema nervoso simpático de pacientes submetidos à hemodiálise / Effect of Carvedilol in the Sympathetic Nervous Sistem on dialisys pacients.
Hemodialysis patients with chronic renal insufficiency always show evidence of hyperactivity of the Sympathetic Nervous System that causes cardiovascular alterations and consequently greater mortality. With the use of Carvedilol in patients with Congestive Heart Failure, improvement in its morbi-mortality was evidenced, that was also verified with the popula
Publicado em: 2008
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14. Efeito do treinamento físico em modelo genético de insuficiência cardíaca induzida por hiperatividade simpática / The Therapeutic effect of exercise training in genetic model of heart failure induced by sympathetic hyperactivity
The sympathetic nervous activity is increased in heart failure (HF) and is associated with the severity and prognosis of disease. Mice lacking both α2A and α2C adrenergic receptors (α2A/α2CARKO) develop sympathetic hyperactivity- induced HF and present 50% mortality rate by seven mo of age. The decreased cardiac contractility, cardiomyocy
Publicado em: 2007
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15. Caracterização fenotípica do músculo esquelético na cardiomiopatia induzida por hiperatividade simpática / Phenotypic characterization of skeletal muscle in cardiomyophatie induced by simpathetic hyperactivity
A insuficiência cardíaca (IC) é uma síndrome clínica de alta incidência e mau prognóstico, caracterizada por fadiga, dispnéia e grande limitação aos esforços físicos. Essas alterações não estão apenas limitadas ao comprometimento cardíaco, mas em parte, são decorrentes também de alterações morfo-funcionais da musculatura esquelética. Pa
Publicado em: 2007
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16. Caracterização da participação do sistema renina-angiotensina na cardiomiopatia induzida por hiperatividade simpática / Characterization of renin-angiotensin system in cardiomyopathy induced by sympathetic hyperactivity
We have recently reported that disruption of both alfa2A and alfa2C adrenergic receptor subtypes (KO) in mice leads to sympathetic hyperactivity with evidence of heart failure (HF) by seven months (mo) of age. In the present study, we have performed the phenotypical characterization on KO mice at three and seven month of age. In addition, we evaluated the ef
Publicado em: 2006
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17. Efeito da terapia com Beta-bloqueadores em camundongos com deleção dos receptores alpha 2A/alpha 2C adrenérgicos / Effects of b- adrenergic antagonist therapy in mice lacking a 2A/a 2C adrenergic receptors
We have recently reported that disruption for both a2A ?and a2C adrenergic receptor subtypes in mice (KO) leads to sympathetic hyperactivity with evidence of heart failure (HF) by the age of 7 months. These mice provide a model system for evaluating the efficiency among different ?- adrenergic antagonists (BB) for HF therapy. In the present study, we evaluat
Publicado em: 2006
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18. Efeito do treinamento físico na cardiomiopatia induzida por hiperatividade simpática em camundongos com ablação dos receptores alpha 2A/alpha 2C- adrenérgicos / Effect of exercise training on cardiomyopathy induced by sympathetic hiperactivity in mice lacking a2A/a2C- adrenoceptors
Presynaptic a2-adrenoceptors (a2 AR) regulate the cardiovascular function by inhibiting neurotransmitter release on the sympathetic nerve terminals. We have recently reported that disruption for both a2A and a2C AR subtypes in mice (KO) leads to sympathetic hyperactivity with evidence of cardiac dysfunction by 4 mo of age. These mice provide a model system f
Publicado em: 2006
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19. AVALIAÇÃO DA SENSIBILIDADE DO BARORREFLEXO EM MODELO EXPERIMENTAL DE HIPERCOLESTEROLEMIA CO-EXISTENTE COM HIPERTENSÃO RENAL
Hypercholesterolemia (HC) and arterial hypertension (AH) are both major risk factors for the development and progression of atherosclerotic heart disease, and their co-existence has been associated with an increased incidence of cardiac events in clinical studies. The baroreflex sensitivity is a very important index in the prognosis of various cardiovascular
Publicado em: 2006
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20. Autonomic nervous system dysfunction in children with severe tetanus: dissociation of cardiac and vascular sympathetic control
The medical records of ten pediatric patients with a clinical diagnosis of tetanus were reviewed retrospectively. The heart rate and blood pressure of all tetanus patients were measured noninvasively every hour during the first two weeks of hospitalization. Six of ten tetanus patients presented clinical evidence of sympathetic hyperactivity (group A) and wer
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-06
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21. Protective effects of centrally acting sympathomodulatory drugs on myocardial ischemia induced by sympathetic overactivity in rabbits
It is recognized that an imbalance of the autonomic nervous system is involved in the genesis of ventricular arrhythmia and sudden death during myocardial ischemia. In the present study we investigated the effects of clonidine and rilmenidine, two centrally acting sympathomodulatory drugs, on an experimental model of centrally induced sympathetic hyperactivi
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-01
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22. Sympathetic Hyperactivity during Hypothalamic Stimulation in Spontaneously Hypertensive Rats
To determine whether sympathetic hyperactivity of hypothalamic origin contributes to keep blood pressures high in spontaneous hypertension, aortic pressures and sympathetic nerve spike potentials were recorded during electrical stimulation of the posterior hypothalamus in urethane-anesthetized normotensive or hypertensive rats. Basal sympathetic nerve activi
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23. Pain—Mechanisms and Management
In the past two decades there has been remarkable progress in understanding the neural mechanisms of pain. However, chronic pain is poorly understood and, by definition, poorly managed. In addition to hyperactivity of the sympathetic nervous system and damage to normal inhibitory mechanisms, social and psychological factors play a major role in producing the
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24. Effects of chronic exposure to arsenate on the cardiovascular function of rats.
Cardiovascular function was studied in anaesthetised male rats which received 50 micrograms/ml of arsenic (as sodium arsenate) in deionised drinking water for 320 days. High urinary excretion of arsenic was found at the end of treatment and the metal accumulated considerably in the kidneys and liver, which both presented slight alterations. No histopathologi