Survival Functions
Mostrando 1-12 de 549 artigos, teses e dissertações.
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1. The promising role of Gelsolin expression to predict survival in patients with squamous cell carcinoma of the larynx
Abstract Introduction: Gelsolin protein has important cellular functions, including cell motility and apoptosis. Altered gelsolin expression has been reported in several types of neoplasms, but clinicopathological features of gelsolin are currently unclear in patients with laryngeal squamous cell carcinoma. Objectives: Our aim is to investigate the clinico
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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2. Serum Long-Noncoding RNA H19 and β-Catenin as Biomarkers for Early Diagnosis of Colorectal Cancer in Egyptian Patients: A Case Control Study
Abstract Colorectal cancer (CRC) is the third most prevalent cancer and the second most common cause of cancer death; however, its early detection can improve the survival. Colonic polyps are considered one of the CRC's major risk factors. Throughout many biological processes and malignancies, the non-coding RNAs have essential functions. Certain long noncod
Journal of Coloproctology (Rio de Janeiro). Publicado em: 2022
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3. Intracardiac Repair in Late Adolescent and Adult Tetralogy of Fallot — Early and Midterm Results from a Tertiary Care Centre
Abstract Introduction: In developing countries like India, it is common for late presentation of Tetralogy of Fallot (TOF) patients to a hospital as compared to that of developed countries. The objective of this study is to analyze the surgical outcome of TOF patients with age > 15 years. Methods: This is a retrospective descriptive study of the surgical o
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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4. Implications of perioperative allogeneic red blood cell transfusion on the immune-inflammatory response
ABSTRACT Background: The allogeneic transfusion-related immunomodulation (TRIM) may be responsible for an increase in survival of renal transplants but in contrast it could increase the rate of bacterial infections or the recurrence rate of tumors post-operatively. Objective: This review focuses in the implications of perioperative allogeneic transfusions
Hematol., Transfus. Cell Ther.. Publicado em: 2021-03
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5. DNA repair genes in astrocytoma tumorigenesis, progression and therapy resistance
Abstract Glioblastoma (GBM) is the most common and malignant type of primary brain tumor, showing rapid development and resistance to therapies. On average, patients survive 14.6 months after diagnosis and less than 5% survive five years or more. Several pieces of evidence have suggested that the DNA damage signaling and repair activities are directly correl
Genet. Mol. Biol.. Publicado em: 13/12/2019
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6. Neuroprotective properties of RT10, a fraction isolated from Parawixia bistriata spider venom, against excitotoxicity injury in neuron-glia cultures
Abstract Background: L-Glutamate (L-Glu), the major excitatory neurotransmitter in the mammalian Central Nervous System (CNS), is essential to cognitive functions. However, when L-Glu is accumulated in large concentrations at the synaptic cleft, it can induce excitotoxicity that results in secondary damage implicated in many neurological disorders. Current
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 16/05/2019
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7. Swallowing in Patients with Mental Disability - Analysis of 189 Swallowing Video Endoscopies
Abstract Introduction Feeding, swallowing and breathing are fundamental activities for the survival and well-being of humans; these functions are performed by themost complex neuromuscular unit of the human body, which, when altered, may raise morbidity and mortality rates. Objective To evaluate deglutition in patients with mental disability in order to
Int. Arch. Otorhinolaryngol.. Publicado em: 25/04/2019
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8. CD47 expression is decreased in hematopoietic progenitor cells in patients with myelofibrosis
Myelofibrosis (MF) is characterized by increased circulating hematopoietic progenitor cells (HPCs), abnormal cytokine levels, and the survival advantage of neoplastic progenitors over their normal counterparts, which leads to progressive disappearance of polyclonal hematopoiesis. CD47 is a surface glycoprotein with many functions, such as acting as a phagocy
Braz J Med Biol Res. Publicado em: 10/12/2018
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9. Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis
The insulin receptor substrate (IRS) proteins are a family of cytoplasmic proteins that integrate and coordinate the transmission of signals from the extracellular to the intracellular environment via transmembrane receptors, thus regulating cell growth, metabolism, survival and proliferation. The PI3K/AKT/mTOR and MAPK signaling pathways are the best-charac
Clinics. Publicado em: 11/10/2018
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10. A new model for describing remission times: the generalized beta-generated Lindley distribution
New generators are required to define wider distributions for modeling real data in survival analysis. To that end we introduce the four-parameter generalized beta-generated Lindley distribution. It has explicit expressions for the ordinary and incomplete moments, mean deviations, generating and quantile functions. We propose a maximum likelihood procedure t
An. Acad. Bras. Ciênc.. Publicado em: 2017-09
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11. Cystometric analysis of the transplanted bladder
ABSTRACT Objective Cystometric evaluation of the bladder after autotransplant and isogeneic transplant in female rats. Material and Methods Two groups were constituted: (A) bladder autotransplant with two subgroups: R1 – (control) and R2 – (bladder transplant); (B) isogeneic bladder transplant with three subgroups; T1 – (control); T2–T3, two subg
Int. braz j urol.. Publicado em: 2017-02
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12. The Complex Link between Apoptosis and Autophagy: a Promising New Role for RB
ABSTRACT Physiological processes, as autophagy, proliferation and apoptosis are affected during carcinogenesis. Restoring cellular sensitivity to apoptotic stimuli, such as the antineoplastic cocktails, has been explored as a strategy to eliminate cancer cells. Autophagy, a physiological process of recycling organelles and macromolecules can be deviated from
An. Acad. Bras. Ciênc.. Publicado em: 2016-12