Surrogate Modeling
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Climatically-mediated landcover change: impacts on Brazilian territory
ABSTRACT In the face of climate change threats, governments are drawing attention to policies for mitigating its effects on biodiversity. However, the lack of distribution data makes predictions at species level a difficult task, mainly in regions of higher biodiversity. To overcome this problem, we use native landcover as a surrogate biodiversity, because i
An. Acad. Bras. Ciênc.. Publicado em: 22/05/2017
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2. Surrogate Modeling Techniques and Heuristic Optimization Methods Applied to Design and Identification Problems / Surrogate modeling techniques and heuristic optimization methods applied to design and identification problems
Avanços na capacidade de processamento computacional popularizaram a otimização numérica como uma ferramenta de engenharia. Contudo, eles favoreceram também o aumento na complexidade das simulações. Como resultado, o custo computacional de simulações complexas de alta fidelidade em engenharia dificultam o uso exclusivo de simulações em otimizaçã
Publicado em: 2008
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3. A study on modeling error estimates in heterogeneous materials structures. / Um estudo sobre estimativas de erro de modelagem em estruturas de materiais heterogêneos.
This work presents a study on modeling error estimates in linear elastic structures of heterogeneous materials. The employed formulation is based on a theory of a posteriori estimation of modeling errors and uses the Finite Element Method as numerical tool. The evaluated modeling errors consist of global errors based on energy norm and local errors in quanti
Publicado em: 2008
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4. Pharmacokinetic/pharmacodynamic relationships of FTY720 in kidney transplant recipients
FTY720 is a new and effective immunosuppressive agent, which produces peripheral blood lymphopenia through a lymphocyte homing effect. We investigated the relationship between the dose of FTY720 or blood concentration (pharmacokinetics, PK) and peripheral lymphopenia (pharmacodynamics, PD) in 23 kidney transplant recipients randomized to receive FTY720 (0.25
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-05
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5. Triple helix formation: binding avidity of acridine-conjugated AG motif third strands containing natural, modified and surrogate bases opposed to pyrimidine interruptions in a polypurine target.
A critical issue for the general application of triple-helix-forming oligonucleotides (TFOs) as modulators of gene expression is the dramatically reduced binding of short TFOs to targets that contain one or two pyrimidines within an otherwise homopurine sequence. Such targets are often found in gene regulatory regions, which represent desirable sites for tri
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6. Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice
The t(12;21) translocation, which generates the TEL-AML1 (ETV6-RUNX1) fusion gene, is the most common structural chromosome change in childhood cancer and is exclusively associated with the common B cell precursor subset of acute lymphoblastic leukemia (ALL). Evidence suggests that the translocation usually occurs in utero during fetal hemopoiesis and most p
National Academy of Sciences.