Sulfonamides
Mostrando 1-12 de 203 artigos, teses e dissertações.
-
1. Synthesis and Biological Evaluation of Novel 1,3-Benzoxathiol-2-one Sulfonamides against Toxic Activities of the Venom of Bothrops jararaca and Bothrops jararacussu Snakes
This work describes the synthesis of new 1,3-benzoxathiol-2-one sulfonamides and evaluation of their ability to inhibit some in vitro (coagulant, proteolytic and hemolytic) and in vivo (hemorrhagic, edematogenic and lethality) toxic activities of Bothrops jararaca and Bothrops jararacussu venoms. Compounds have been synthesized from the coupling of intermedi
Journal of the Brazilian Chemical Society. Publicado em: 2022
-
2. Synthesis of new 2-{2,3-dihydro-1,4-benzodioxin-6-yl[(4-methylphenyl) sulfonyl]amino}-N-(un/substituted-phenyl)acetamides as α-glucosidase and acetylcholinesterase inhibitors and their in silico study
The aim of the present research work was to investigate the enzyme inhibitory potential of some new sulfonamides having benzodioxane and acetamide moieties. The synthesis was started by the reaction of N-2,3-dihydrobenzo[1,4]-dioxin-6-amine (1) with 4-methylbenzenesulfonyl chloride (2) in the presence of 10% aqueous Na2CO3 to yield N-(2,3-dihydrobenzo[1,4]-d
Braz. J. Pharm. Sci.. Publicado em: 15/08/2019
-
3. Perfil de resistência antimicrobiana de Klebsiella pneumoniae isoladas de animais domésticos e silvestres
RESUMO Klebsiella pneumoniae é um patógeno oportunista, responsável por diversos tipos de infecções nosocomiais, e é considerado um microrganismo multirresistente. Dados na literatura que forneçam informações a respeito da resistência desse microrganismo a antimicrobianos em amostras de animais são escassos. Dessa forma, o objetivo deste trabalho
Arq. Bras. Med. Vet. Zootec.. Publicado em: 06/06/2019
-
4. Antimicrobial Susceptibility and Biofilm Production by Salmonella sp. Strains Isolated from Frozen Poultry Carcasses
ABSTRACT The objectives of this study were to evaluate the antimicrobial resistance and the biofilm-producing ability of Salmonella sp. strains isolated from frozen poultry carcasses. Antimicrobial susceptibility was tested by the disk-diffusion method. Biofilm-producing ability was determined in 96-well polystyrene microplates stained with crystal violet at
Rev. Bras. Cienc. Avic.. Publicado em: 2017-03
-
5. Sorption of Sulfachloropyridazine in Brazilian Soils
Sulfonamides are among the most widely employed antibacterial in veterinary medicine. Because a substantial proportion of sulfonamides are excreted unchanged as parent compounds after administration or are excreted as their metabolites through urine and feces, their presence in soils is a matter of concern. Adsorption and desorption are important processes t
J. Braz. Chem. Soc.. Publicado em: 2017-01
-
6. Validation of a LC-MS/MS Multiresidue Methodology Based on a QuEChERS Approach for the Determination of Fluoroquinolones, Sulfonamides and Trimethoprim in Poultry and Porcine Kidney According to the Normative Instruction 24/2009-MAPA
This work involved the validation of a multiresidue method according to the Normative Instruction 24/2009-MAPA for determining 25 analytes, among fluoroquinolones, sulfonamides and trimethoprim in samples of poultry and porcine kidney. The extraction procedure was based on a QuEChERS approach. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) metho
J. Braz. Chem. Soc.. Publicado em: 2017-01
-
7. Voltammetric Determination of Sulfonamides with a Modified Glassy Carbon Electrode Using Carboxyl Multiwalled Carbon Nanotubes
New glassy carbon electrode (GCE) modified with carboxyl multiwalled carbon nanotubes (MWCNTs) and treated with ultrasonic dispersing in N,N-dimethylfomamide (DMF) media, namely DMF/carboxyl/MWCNTs/GCE, was prepared for electrochemical determination of sulfonamides (SAs). Electrochemical behavior of SAs based on DMF/carboxyl/MWCNTs/GCE was investigated by cy
J. Braz. Chem. Soc.. Publicado em: 2016-12
-
8. The importance of integrons for development and propagation of resistance in Shigella: the case of Latin America
Abstract In Latin America, the disease burden of shigellosis is found to coexist with the rapid and rampant spread of resistance to commonly used antibiotics. The molecular basis of antibiotic resistance lies within genetic elements such as plasmids, transposons, integrons, genomic islands, etc., which are found in the bacterial genome. Integrons are known t
Braz. J. Microbiol.. Publicado em: 2016-12
-
9. Development of a rapid method for the determination of antibiotic residues in honey using UPLC-ESI-MS/MS
Abstract An accurate, reliable and fast multianalyte/multiclass ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method was developed and validated for the simultaneous analysis of 23 pharmaceuticals, belonging to different classes amphenicols, sulfonamides, tetracyclines, in honey samples. The method developed consists of ul
Food Sci. Technol. Publicado em: 26/02/2016
-
10. Characterization of antibiotic resistance in Salmonella enterica isolates determined from ready-to-eat (RTE) salad vegetables
In the last decade, ready-to-eat (RTE) salad vegetables are gaining increasing importance in human diet. However, since they are consumed fresh, inadequate washing during processing can bring on some foodborne illnesses, like salmonellosis, since these food items have natural contamination from soil and water. During 2009-2010, a total of 81 samples were pur
Braz. J. Microbiol.. Publicado em: 30/08/2013
-
11. QSAR-3D/CoMFA em compostos imídicos com atividade antinociceptiva
Imide compounds have shown biological activity. These compounds can be easily synthesized with good yields. The objective of this paper was the rational planning of imides and sulfonamides with antinociceptive activity using the 3D-QSAR/CoMFA approach. The studies were performed using two data sets. The first set consisted of 39 cyclic imides while the secon
Quím. Nova. Publicado em: 2013
-
12. OTIMIZAÇÃO E VALIDAÇÃO DE MÉTODO ANALÍTICO PARA PREPARO DA AMOSTRA E DETERMINAÇÃO SIMULTÂNEA DE SULFONAMIDAS EM MEL / OPTIMIZATION AND VALIDATION OF ANALYTICAL METHOD FOR PREPARING OF THE SAMPLE AND SIMULTANEOUS DETERMINATION OF SULPHONAMIDES IN HONEY
This work presents and discusses the results of the validation of a method for determination of sulfonamide residues in honey bees africanized of the Alto Turi - MA. In preparation of the honey samples, was used acid hydrolysis and employed a system of solid phase extraction in cartridge ABS - Elut Nexus. The eluate was analyzed by liquid chromatography with
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/12/2012