Succinate Dehydrogenase
Mostrando 1-12 de 360 artigos, teses e dissertações.
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1. Evaluation of Reference Genes for Quantitative PCR in Four Tissues from Rabbits with Hypercholesterolaemia
Abstract Rabbit with hypercholesterolaemia is an important model for studying cholesterol metabolism disease. This study aimed to evaluate the expression stability of nine reference genes for quantitative PCR (qPCR) analysis in adrenal gland, liver, spleen, and kidney tissue from rabbits with hypercholesterolaemia. In total, 30 male Harbin Large White (HLW)
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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2. Effects of different frequencies of physical training on electron transport chain and oxidative damage in healthy mice
Abstract Aims: The present study investigated the effect of different frequencies (three and five times a week) on electron transport chain and oxidative stress after 8 weeks of run training. Methods: Eighteen male mice (CF1, 30-35g) were distributed into the following groups (n=6): untrained (UT); trained three-time per week (T3) and trained five- time
Motriz: rev. educ. fis.. Publicado em: 23/11/2018
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3. Urological cancer related to familial syndromes
ABSTRACT Cancer related to hereditary syndromes corresponds to approximately 5-10% of all tumors. Among those from the genitourinary system, many tumors had been identified to be related to genetic syndromes in the last years with the advent of new molecular genetic tests. New entities were described or better characterized, especially in kidney cancer such
Int. braz j urol.. Publicado em: 2017-04
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4. Fluvoxamine alters the activity of energy metabolism enzymes in the brain
Objective: Several studies support the hypothesis that metabolism impairment is involved in the pathophysiology of depression and that some antidepressants act by modulating brain energy metabolism. Thus, we evaluated the activity of Krebs cycle enzymes, the mitochondrial respiratory chain, and creatine kinase in the brain of rats subjected to prolonged adm
Rev. Bras. Psiquiatr.. Publicado em: 17/03/2014
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5. Effect of exposure to sublethal concentrations of sodium cyanide on the carbohydrate metabolism of the Indian Major Carp Labeo rohita (Hamilton, 1822)
Experiments were designed to study in-vivo effects of sodium cyanide on biochemical endpoints in the freshwater fish Labeo rohita. Fish were exposed to two sublethal concentrations (0.106 and 0.064mg/L) for a period of 15 days. Levels of glycogen, pyruvate, lactate and the enzymatic activities of lactate dehydrogenase (LDH), succinate dehydrogenase (SDH), gl
Pesq. Vet. Bras.. Publicado em: 2013-07
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6. Effect of eccentric training on mitochondrial function and oxidative stress in the skeletal muscle of rats
The objective of the present study was to investigate the effects of eccentric training on the activity of mitochondrial respiratory chain enzymes, oxidative stress, muscle damage, and inflammation of skeletal muscle. Eighteen male mice (CF1) weighing 30-35 g were randomly divided into 3 groups (N = 6): untrained, trained eccentric running (16°; TER), and
Braz J Med Biol Res. Publicado em: 11/01/2013
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7. Over-representation of the G12S polymorphism of the SDHD gene in patients with MEN2A syndrome
OBJECTIVE: To evaluate whether germline variants of the succinate dehydrogenase genes might be phenotypic modifiers in patients with multiple endocrine neoplasia type 2. Mutations of genes encoding subunits of the succinate dehydrogenase are associated with hereditary paraganglioma/pheochromocytoma syndrome. Pheochromocytoma is one of the main manifestations
Clinics. Publicado em: 2012
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8. Evaluation of reference genes for real-time PCR studies of Brazilian Somalis sheep infected by gastrointestinal nematodes.
Precise normalization with reference genes is necessary, in order to obtain reliable relative expression data in response to gastrointestinal nematode infection. By using sheep from temperate regions as models, three reference genes, viz., ribosomal protein LO (RPLO), glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and succinate dehydrogenase complex subuni
Genetics and Molecular Biology. Publicado em: 2011
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9. Biomphalaria alexandrina snails as immunogens against Schistosoma mansoni infection in mice
Despite effective chemotherapy, schistosomiasis remains the second largest public health problem in the developing world. Currently, vaccination is the new strategy for schistosomiasis control. The presence of common antigenic fractions between Schistosoma mansoni and its intermediate host provides a source for the preparation of a proper vaccine. The object
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-11
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10. Evaluation of reference genes for real-time PCR studies of Brazilian Somalis sheep infected by gastrointestinal nematodes
Precise normalization with reference genes is necessary, in order to obtain reliable relative expression data in response to gastrointestinal nematode infection. By using sheep from temperate regions as models, three reference genes, viz., ribosomal protein LO (RPLO), glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and succinate dehydrogenase complex subuni
Genetics and Molecular Biology. Publicado em: 2010
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11. β - NADH DIMINUI A SENSIBILIDADE DA SUCINATO DESIDROGENASE A INIBIÇÃO POR ÁCIDO METILMALÔNICO / β-NADH REDUCES SUCCINATE DEHYDROGENASE SENSITIVITY TO THE COMPETITIVE INHIBITOR METHYLMALONIC ACID IN CEREBRAL CORTEX OF RATS
Methylmalonic acidemia, one of the most frequent organic acidemias, is caused by deficiency of the methylmalonyl CoA mutase, leading to tissue accumulation of Lmethylmalolonic acid (MMA). Affects individuals present lethargy, coma, vomiting, muscular hypotonia, recurrent episodes of metabolic acidosis and progressive encephalopathy. In this context, it has b
Publicado em: 2007
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12. Mutation screening in the VHL, SDHB and SDHD genes in patients with sporadic pheochromocytoma and/or paraganglioma / Rastreamento de mutações nos genes VHL, SDHB e SDHD em pacientes portadores de feocromocitoma ou também, paraganglioma esporádico
Pheochromocytomas are neuroendocrine tumors composed of chromaffin cells that produce and secrete catecholamines as well as a variety of neuropeptides, whose most common clinical manifestation is arterial hypertension. Twelve to 24% of the apparently sporadic pheochromocytomas, present germline mutations in genes previously associated to inherited familiar s
Publicado em: 2007