Strain Me 49
Mostrando 1-12 de 35 artigos, teses e dissertações.
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1. Histopathology of murine toxoplasmosis under treatment with dialyzable leukocyte extract
BACKGROUND Dialyzable leukocyte extracts (DLEs) contain molecules smaller than 10 kDa with biological activity in receptor organisms. Primarily, they participate in the regulation of the Th1 immune response, which is essential for the control of several intracellular infections, such as toxoplasmosis. This disease is associated with congenital infection, en
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-11
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2. CD19 LYMPHOCYTE PROLIFERATION INDUCED BY Bifidobacterium animalis subsp. lactis IN C57BL/6 MICE EXPERIMENTALLY INFECTED WITH Toxoplasma gondii
Toxoplasmosis is frequently acquired through the oral route by the ingestion of cysts or oocysts of Toxoplasma gondii. Once ingested, the parasites penetrate the intestinal epithelial cells and rapidly disseminate to all organs in the host. During T. gondii infection, the intestinal microbiota plays an important role in stimulating a protective immune respon
Rev. Inst. Med. trop. S. Paulo. Publicado em: 08/04/2016
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3. Experimental infection with the Toxoplasma gondii ME-49 strain in the Brazilian BR-1 mini pig is a suitable animal model for human toxoplasmosis
Toxoplasma gondii causes toxoplasmosis, a worldwide disease. Experimentation with pigs is necessary for the development of new therapeutic approaches to human diseases. BR-1 mini pigs were intramuscularly infected with T. gondii with tachyzoites (RH strain) or orally infected with cysts (ME-49 strain). Haematology and serum biochemistry were analysed and buf
Mem. Inst. Oswaldo Cruz. Publicado em: 03/02/2015
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4. Apoptose e proliferação celular em células trofoblásticas (linhagem BeWo) são diferentemente moduladas pelas cepas de Toxoplasma gondii
Transplacental transmission causes one of the most severe forms of infection with protozoan parasite Toxoplasma gondii. The ability of the parasite to survive intracellularly largely depends on the blocking of different proapoptotic signaling cascade of its host cell. However, alterations in the incidence of apoptosis, during pregnancy, are associated with a
Publicado em: 2009
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5. Azitromicina inibe a infecção por Toxoplasma gondii em oculares de fetos e reduz o parasitismo na infecção congênita e adquirida em modelo experimental de Calomys callosus
Toxoplasma gondii is an obligatory intracelullar parasite of large geographical distribution that causes severe sequelae to fetuses of mothers infected for the first time during pregnancy and in immunossuppressed adults. The drugs most frequently used for the treatment of toxoplasmosis are a combination of sulfadiazine and pirimethamine plus folinic acid. Ho
Publicado em: 2008
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6. Azitromicina inibe a infecÃÃo por Toxoplasma gondii em oculares de fetos e reduz o parasitismo na infecÃÃo congÃnita e adquirida em modelo experimental de Calomys callosus
Toxoplasma gondii is an obligatory intracelullar parasite of large geographical distribution that causes severe sequelae to fetuses of mothers infected for the first time during pregnancy and in immunossuppressed adults. The drugs most frequently used for the treatment of toxoplasmosis are a combination of sulfadiazine and pirimethamine plus folinic acid. Ho
Publicado em: 2008
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7. Detection of Toxoplasma gondii DNA in sera samples of mice experimentally infected
Detection of Toxoplasma gondii (T. gondii) DNA in blood can help to diagnose the disease in its acute phase; however, it must be considered that hemoglobin, present in blood, can inhibit polymerase activity, making impracticable the detection of DNA in samples. Mice were experimentally infected via oral route with ME49 and BTU2 strains cysts and RH strain ta
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2006-04
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8. Mastócitos de camundongos BALB/c e C57BL/6 e a susceptibilidade a infecção por Toxoplasma gondii (cepas RH e ME-49)
No presente trabalho estudou-se: as características morfológicas e ultra-estruturais dos mastócitos peritoneais de camundongos BALB/c e C57BL/6 e as modificações ocorridas nestes mastócitos após 24 e 48 horas de infecção com a cepa RH de T. gondii; o número de mastócitos, neutrófilos, macrófagos e linfócitos do exsudato peritoneal de camundongo
Publicado em: 2005
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9. Infestação prévia com Myocoptes musculinus altera a resposta imune induzida por Toxoplasma gondii
Toxoplasma gondii is na obligate intracellular parasite that induces a Th1 immune response, in both resistant, BALB/c and susceptible, C57BLL/6, lineages of mice to this parasite. Myocoptes musculinus is a mite that induces a Th2 immune response. In this research wokr was investigated wheter chronic infestation with the M. musculinus influences in the immuno
Publicado em: 2005
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10. Detection of Toxoplasma gondii DNA by polymerase chain reaction in experimentally desiccated tissues
Despite toxoplasmosis being a common infection among human and other warm-blooded animals worldwide, there are no findings about Toxoplasma gondii evolutionary forms in ancient populations. The molecular techniques used for amplification of genetic material have allowed recovery of ancient DNA (aDNA) from parasites contained in mummified tissues. The applica
Memórias do Instituto Oswaldo Cruz. Publicado em: 2004-03
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11. "Toxoplasma gondii vs radiação ionizante: Estudo da imunidade intestinal em camundongos C57Bl/6j experimentalmente vacinados com taquizoítos irradiados" / Toxoplasma gondii vs ionizing radiation: Intestinal immunity induced in C57bl/6j mice by irradiated tachyzoites
We study the oral route for the development of a vaccine for toxoplasmosis, using parasites irradiated with 60 Cobalt, as an alternative for vaccine development to this worldwide parasitic infection. We evaluated the development of immunity at serum or mucosal levels, and their efficiency in protect the mice against challenge with oral cysts of the ME-49 str
Publicado em: 2004
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12. Long-Term Immunity to Lethal Acute or Chronic Type II Toxoplasma gondii Infection Is Effectively Induced in Genetically Susceptible C57BL/6 Mice by Immunization with an Attenuated Type I Vaccine Strain▿
C57BL/6 (B6) mice are genetically highly susceptible to chronic type II Toxoplasma gondii infections that invariably cause lethal toxoplasmic encephalitis. We examined the ability of an attenuated type I vaccine strain to elicit long-term immunity to lethal acute or chronic type II infections in susceptible B6 mice. Mice immunized with the type I cps1-1 vacc
American Society for Microbiology (ASM).