Spasmolytic Effect
Mostrando 1-12 de 12 artigos, teses e dissertações.
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1. Effects of dipyrone on the digestive tract
Dipyrone (metamizole), acting through its main metabolites 4-methyl-amino-antipyrine and 4-amino-antipyrine, has established analgesic, antipyretic, and spasmolytic pharmacological effects, which are mediated by poorly known mechanisms. In rats, intravenously administered dipyrone delays gastric emptying (GE) of liquids with the participation of capsaicin-se
Braz J Med Biol Res. Publicado em: 10/01/2019
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2. Antibacterial, anti-swarming and anti-biofilm formation activities of Chamaemelum nobile against Pseudomonas aeruginosa
AbstractINTRODUCTION:Chamomile ( Chamaemelum nobile ) is widely used throughout the world, and has anti-inflammatory, deodorant, bacteriostatic, antimicrobial, carminative, sedative, antiseptic, anti-catarrhal, and spasmolytic properties. Because of the increasing incidence of drug-resistant bacteria, the development of natural antibacterial sources such as
Rev. Soc. Bras. Med. Trop.. Publicado em: 2015-08
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3. Antispasmodic effects of Aloysia polystachya and A. gratissima tinctures and extracts are due to non-competitive inhibition of intestinal contractility induced by acethylcholine and calcium
The antispasmodic effects of acqueous extracts (AE) and tinctures (T) of Aloysia polystachya (Griseb.) Moldenke and Aloysia gratissima (Gillies & Hook.) Tronc., Verbenaceae, were studied on rat isolated ileum and duodenum. These plants are used for gastrointestinal disorders and as eupeptic in South America. Both AE non-competitively inhibited the dose-respo
Revista Brasileira de Farmacognosia. Publicado em: 12/08/2011
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4. Participação Do Cálcio Citosólico Sobre A Ação Espasmolítica Do Ácido Ent-7a-Acetoxitraquiloban-18-Óico E De Seu Derivado Hidroxilado Em Íleo Isolado De Cobaia / Partipation of cytosolic calcium in spasmolytic action of ent-7a-acetoxytrachyloban-18-oic acid and its hidroxylated derivated on guinea-pig ileum
From the stem bark of Xylopia langsdorfiana A. St.-Hil. &Tul. (Annonaceae), popularly known as pimenteria da terra, was isolated the diterpene ent-7-α-acetoxytrachyloban-18-oic acid (trachylobane-360) from which it was made a structural modification in which the acetoxy group was substituted by hydroxy generating the ent-7a-hidroxitrachyloban-18-oic aci
Publicado em: 2010
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5. Efeito de hypericum caprifoliatum cham. & schltdl. (guttiferae) sobre contrações em íleo isolado de cobaio induzidas por diferentes agonistas / Effect of Hypericum caprifoliatum Cham & Schltdl (Guttiferae) on isolated guinea pig ileum serotonin response
Na última década, o gênero Hypericum ganhou repercussão mundial devido à utilização de Hypericum perforatum para obtenção de medicamentos antidepressivos. Por esta razão, a maioria dos estudos com outras espécies do gênero centra-se nesta atividade. Porém, um dos usos populares de espécies de Hypericum nativas do sul do Brasil é no tratamento
Publicado em: 2010
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6. Participation of the muscarinic receptors and of the nitric oxide pathway in the spasmolytic effect of the total alkaloids fraction obtained from Solanum paludosum Moric. (SOLANACEAE) / Participação de receptores muscarínicos e da via do óxido nítrico no efeito espasmolítico da fração de alcalóides totais obtida de Solanum paludosum Moric: (Solanaceae)
Solanum paludosum Moric. (Solanaceae) é uma espécie herbácea, conhecida popularmente como jurubeba-roxa no Nordeste do Brasil (AGRA; BHATTACHARYYA, 1999). O estudo químico e farmacológico com a casca da raiz desta espécie mostrou a presença de glicoalcalóides, e que o extrato etanólico e a fase aquosa obtidos da mesma parte mostraram atividade espas
Publicado em: 2009
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7. Estudo do efeito Antinociceptivo do Eugenol / Study of the antinociceptive effect of Eugenol
Eugenol is a fenolic derivative being chemically designated as 4-alil-2-metóxifenol, well-known usually as carnation essence, because this present in great quantity in the essential oil of carnation of India (Eugenia aromatic), but this present also in the cinnamon, sassafras and myrrh. Eugenol bears several pharmacological effects among them can highlight:
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/01/2008
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8. Envolvimento dos canais de potássio na ação espasmolítica do ácido 8(17), 12E, 14-labdatrieno-18-óico (labdano-302), isolado de Xylopia langsdorfiana A. St.-Hil. &Tul. em íleo isolado de cobaia / Involvement of potassium channels in the spasmolytic action of 8(17),12E, 14-labdatrien-18 oic acid (labdane-302), obtained from Xylopia langsdorfiana A. St.-Hil. &Tul. on guinea-pig ileum
8(17),12e,14-labdatrien-18 oic acid (labdane-302), is a diterpene isolated from the stem bark of Xylopia langsdorfiana A. St.-Hil. &Tul. In a preliminary study, Ribeiro (2003) demonstrated that labdane-302 inhibited the phasic contractions induced by carbachol (CCh) or histamine (IC50 = 1.7 0.5 and 0.9 0.2 x 10-5 M, respectively) on guinea-
Publicado em: 2008
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9. SÃntese e caracterizaÃÃo de novos derivados mesoiÃnicos para aplicaÃÃo de Ãptica nÃo-linear e atividade biolÃgica
Mesoionic compounds constitute a group of heterocyclic betaines stabilized by delocalisation of electrons and charge, the synthesis of which has proven of great interest. This stemmed from (a) their wide range of biological activity with a considerable possibility of obtaining pharmaceuticals; (b) their special physical properties for non-linear optics appli
Publicado em: 2004
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10. Efeitos farmacologicos de alcaloides benzil-isoquinolicos sobre a musculatura traqueal de cobaias
The pharmacological effects of five benzyl - isoquinoline alkaloids were studied on the isolated perfused guinea-pig tracheal chain. The decreasing order of the spasmolytic activity exerted is: papaverine, demethoxy-papaverine, papaverinol, dioxymethverine and nitro-papaverine. The recovery of the contractile responses to carbachol depends upon the magnitude
Publicado em: 1983
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11. Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway.
The trefoil peptides, a recently recognized family of protease-resistant peptides, expressed in a regional specific pattern throughout the normal gastrointestinal tract. Although these peptides have been hypothesized to act as growth factors, their functional properties are largely unknown. Addition of recombinant trefoil peptides human spasmolytic polypepti
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12. Increased airway reactivity in the guinea-pig follows exposure to intravenous isoprenaline.
1. Intravenous infusion of (+/-) isoprenaline (1-100 micrograms kg-1 h-1) enhanced airway responses (resistance, RL; and compliance, Cdyn) to histamine (1.0-1.8 micrograms kg-1) and bombesin (100-240 ng kg-1), whereas airway responses to vagal stimulation remained unchanged. 2. Bilateral vagotomy before intravenous infusion of (+/-)isoprenaline (100 microgra