Solvent Evaporation Technique
Mostrando 1-12 de 45 artigos, teses e dissertações.
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1. Silymarin-Laden PVP-Nanocontainers Prepared Via the Electrospraying Technique for Improved Aqueous Solubility and Dissolution Rate
Abstract The aim of the present research was to develop a silymarin-laden PVP-nanocontainer providing ameliorated aqueous solubility and dissolution of the drug. Several silymarin-laden formulations were formed with varying quantities of PVP and SDS via the solvent evaporation method using the electrospraying technique. The influence of the hydrophilic carri
Braz. arch. biol. technol.. Publicado em: 28/11/2019
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2. Desenvolvimento e caracterização de membranas de quitosana / Cissus Verticillata (L.) Nicolson & C.E. Jarvis
RESUMO Os polímeros, devido às suas diversas aplicações e funcionalidades, estão entre os excipientes mais utilizados para a obtenção de formas farmacêuticas, ganhando destaque a quitosana. O objetivo deste trabalho foi desenvolver e avaliar comparativamente membranas de quitosana com diferentes concentrações da espécie vegetal Cissus verticillata
Matéria (Rio J.). Publicado em: 16/09/2019
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3. Pharmacological and toxicological investigations of etodolac loaded gum katira microspheres prepared by W1/O/W2 emulsion solvent evaporation technique in rats
ABSTRACT Etodolac is a non-steroidal anti-inflammatory drug (NSAID) and approved by USFDA as a COX2 inhibitor. Although etodolac therapy provides clinical benefits, it is associated with upper gastrointestinal (GI) tract complications also. Etodolac loaded gum Katira microsphere (ELGKM) was prepared by W1/O/W2 emulsion solvent evaporation technique. The gast
Braz. J. Pharm. Sci.. Publicado em: 09/04/2018
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4. Fibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinning
Rotary jet spinning (RJS) and electrospinning are techniques to obtain fibrous scaffolds. RJS is a simple method, which fabricates three-dimensional fibers by exploiting a high-speed rotating nozzle, creating a polymer jet which stretches until solidification, and does not require high voltage. In opposite, electrospinning technique needs the presence of an
Mat. Res.. Publicado em: 15/03/2018
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5. Menthol-loaded PLGA Micro and Nanospheres: Synthesis, Characterization and Degradation in Artificial Saliva
Menthol-loaded PLGA micro/nanospheres were synthesized using the multiple emulsion/solvent evaporation technique. Parameters such as stirring rate, external surfactant content, PLGA/menthol weight ratio, solvent evaporation and lyophilization time were evaluated as well as the degradation of micro/nanospheres in an artificial saliva medium. The menthol/PLGA
Mat. Res.. Publicado em: 15/02/2018
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6. Development and Validation of a Stability-Indicating Method for Perillyl Alcohol Incorporated in Poly(lactide-co-glycolide) Nanoparticles and Stress Degradation Studies
Perillyl alcohol has been studied in the treatment of cancer disease. However, its high toxicity is a drawback, which can be overcome by its incorporation in nanostructured systems. The aim of this work was to develop and validate a chromatographic method for determination of perillyl alcohol encapsulation efficiency in a polymeric nanoparticles formulation
J. Braz. Chem. Soc.. Publicado em: 2017-12
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7. Synthesis and Characterization of Non-Linear Optical Crystal of Manganese Mercury Thiocyanate Glycol Monomethyl Ether
The design and synthesis of organic nonlinear optical (NLO) crystals are a promising area of current research in materials science. Organic materials are found to possess better non linear optical properties when compared to inorganic materials. Recently, there has been a widespread interest in the metal-organic coordination compounds, which are a combinatio
Mat. Res.. Publicado em: 30/11/2017
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8. Effects of bone morphogenetic protein-2 (BMP-2) and vascular endothelial growth factor (VEGF) release from polylactide-poly (ethylene glycol)-polylactide (PELA) microcapsule-based scaffolds on bone
Multiple growth factors can be administered to mimic the natural process of bone healing in bone tissue engineering. We investigated the effects of sequential release of bone morphogenetic protein-2 (BMP-2) and vascular endothelial growth factor (VEGF) from polylactide-poly (ethylene glycol)-polylactide (PELA) microcapsule-based scaffolds on bone regeneratio
Braz J Med Biol Res. Publicado em: 30/11/2017
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9. Evaluation of polymeric PLGA nanoparticles conjugated to curcumin for use in aPDT
ABSTRACT Antimicrobial photodynamic therapy (aPDT) involves the association of a photosensitizing agent with a light source with the goal of causing apoptosis or microbial lysing. The use of compounds with natural active principles is gaining prominence throughout the world. Several studies from groups that are linked to the development of innovations in the
Braz. J. Pharm. Sci.. Publicado em: 20/07/2017
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10. Development and Characterization of Synthetic Chalcones-Loaded Eudragit RS 100 Microparticles for Oral Delivery
Eudragit® RS100 microspheres of two chalcones were prepared by solvent evaporation technique. A simple and rapid high-performance liquid chromatography (HPLC) method was developed and validated to determine the encapsulation efficiency, drug loading and release profiles of these chalcones in a microparticulate system. The mean EE values for the two chalcone
J. Braz. Chem. Soc.. Publicado em: 2017-06
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11. The effect of andiroba oil and chitosan concentration on the physical properties of chitosan emulsion film
Abstract Chitosan film is used as a dressing to heal burns. The physical and biological properties of the film can be modified by the addition of phytotherapic compounds. This work used the casting -solvent evaporation technique to prepare chitosan film containing andiroba oil (Carapa guianensis) which has anti-inflammatory, antibiotic, and healing propertie
Polímeros. Publicado em: 14/06/2016
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12. Preparation and characterization of collagen microspheres for sustained release of steroidal saponins
Steroidal saponins are the major pharmacological constituents of ophiopogon japonicus which have been used to treat bone and joint diseases, nerve damage, and hematischesis for hundreds of years in China. The objective of this study was to investigate the therapeutic potential of collagen microspheres loaded with steroidal saponins as an inducer factor for s
Mat. Res.. Publicado em: 2014-12