Solid Phase Organic Synthesis
Mostrando 1-12 de 17 artigos, teses e dissertações.
-
1. Synthesis and characterization of a linker for primary amines used in the solid phase organic synthesis of spermidine
Neste trabalho é descrita a preparação de uma resina modificada, empregada como linker para a preparação de espermidina funcionalizada, em bom rendimento, assim como sua caracterização por infravermelho (IV), ressonância magnética nuclear de 13C no estado sólido com polarização cruzada e rotação no ângulo mágico (RMN-CPMAS de 13C) e ressonân
Journal of the Brazilian Chemical Society. Publicado em: 2011-01
-
2. Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
Dihydropirimidinones (DHPMs) are molecules whose synthesis is known since 1893, and lately has been receiving increased attention due to its diversity of pharmacological actions, such as: anti-tumor activity, antiviral, antiinflammatory, calcium channel blocker and antiparasitic. In our study, we performed the synthesis of DHPM, its hydrolysis by conventiona
Publicado em: 2010
-
3. Highlights in the solid-phase organic synthesis of natural products and analogues
Neste trabalho nós apresentamos uma revisão sobre a síntese em fase sólida de metabólitos secundários, tais como alcalóides, poliaminas, esteróides, terpenos e flavonóides, descritos na literatura a partir de 2000. Um número considerável de rotas sintéticas elegantes e desafiadoras, usando suportes sólidos, será discutido.
Journal of the Brazilian Chemical Society. Publicado em: 2010
-
4. Síntese, caracterização estrutural, termoquímica e elétrica de materiais cerâmicos para células a combustível de óxido sólido / Synthesis, structural, thermochemical and electrical characterization of ceramic materials for solid oxide fuel cells
Nanocrystalline yttria or scandia stabilized zirconia (YSZ, ScSZ) powders with fluorite-type structure were synthesized by the polyacrylamide, the polymeric precursor and the precipitation methods. Powders were characterized by X-ray diffraction (XRD), simultaneous (TG and DTA or DSC) thermal analysis, nitrogen adsorption analysis, scanning electron microsco
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/12/2008
-
5. Molecularly imprinted polymers (MIPs) as solid phase extractors in flow systems / Polímeros molecularmente impressos (MIPs) como extratores em fase sólida em sistemas de análises em fluxo
Molecularly imprinted polymers (MIPs) are promising as material to be used in solid phase extractions due to their high selectivity. MIPs selectivity is directly related to the recognition of a molecule of interest, which was previously employed as template in the synthesis process. The main favorable characteristics of MIPs are the easy preparation, low cos
Publicado em: 2008
-
6. Síntese em fase sólida e em solução de anéis pirrolizidínicos e avaliação da atividade carrapaticida contra rhipicephalus (boophilus) microplus / Solid and solution-phase synthesis of pyrrolizidines and the evaluation of its activity against the cattle tick Rhipicephalus (Boophilus) microplus
No presente trabalho desenvolveu-se uma rota sintética em fase sólida para obter de forma rápida o esqueleto da hiacintacina 110 utilizando-se L-Boc-prolina 101 como bloco de construção. Não há relatos na literatura, até o momento, do uso da Lprolina como material de partida para a síntese de núcleos pirrolizidínicos, entretanto o estudo desta rot
Publicado em: 2008
-
7. INFLUENCIA DA IDADE DE REBROTA SOBRE O POTENCIAL NUTRICIONAL DO FENO DE QUICUIO (PENNISETUM CLANDESTINUM) CONSUMIDO POR OVINOS / REGROWTH AGE INGLUENCE ON THE POTENTIAL NUTRITIONAL ASSESSMENT OF KIKUYU GRASS HAY (Pennisetum clandestinum) IN SHEEPS
Two experiments were conducted to evaluate changes in chemical composition on kikuyu Pennisetum clandestinum hay cut with 50, 70 and 90 days of regrowth, and its effect on intake, digestibility, ruminal fermentation and passage kinetics of solid phase through gastrointestinal tract (Experiment 1) and oxygen utilization by the portal system (Experiment 2) in
Publicado em: 2007
-
8. Solid-phase organic synthesis of sensing sorbent materials for copper and lead recovery
A síntese de materiais para retenção e/ou pré-concentração de espécies de interesse clínico e ambiental, como íons metálicos, constitui uma importante área de pesquisa atual. Neste trabalho, descrevemos a síntese de diferentes suportes sólidos de antraceno - sulfeto de fosfina para pré-concentração de Cu(II) e Pb(II). As propriedades sensoras
Journal of the Brazilian Chemical Society. Publicado em: 2005-06
-
9. O uso do forno de microondas na síntese orgânica em fase sólida
Solid-phase organic synthesis (SPOS) has been considered the main strategy for the construction of combinatorial libraries, because its simplicity leads to faster synthetic procedures. In addition to that, a series of reports in the specialized literature show great advantages in the use of microwave activation, when compared to classical heating, for instan
Química Nova. Publicado em: 2005-02
-
10. Synthesis, characterization and study of catalytical properties of mixed layered hydroxides containing Cu(II)/Mg(II)/Al(III) / Síntese, caracterização e estudo de propriedades catalíticas de hidróxidos mistos lamelares contendo Cu(II)/Mg(II)/AI(III)
In this work it was investigated the preparation and spectroscopic characterization of layered hydroxides of composition [Mg3-xCuxAl(OH)8](CO3)0.5.yH2O (x = 0.3; 0.6; 0.9; 1.2; 1.5; 1.8; 2.1; 2.4; 2.7 and 3.0), as well the reactivity of these materials towards phenol hydroxylation, using hydrogen peroxide as oxidizing agent. The solids had been prepared thro
Publicado em: 2005
-
11. The ue of polysiloxane/polyvinyl alcohol beads as solid phase in IgG anti-Toxocara canis detection using a recombinant antigen
Immunodetection of human IgG anti-Toxocara canis was developed based on ELISA and on the use of polysiloxane/polyvinyl alcohol (POS/PVA) beads. A recombinant antigen was covalently immobilized, via glutaraldehyde, onto this hybrid inorganic-organic composite, which was prepared by the sol-gel technique. Using only 31.2 ng antigen per bead, a peroxidase conju
Memórias do Instituto Oswaldo Cruz. Publicado em: 2003-04
-
12. Polysiloxane/PVA-glutaraldehyde hybrid composite as solid phase for immunodetections by ELISA
We developed an efficient method to prepare a hybrid inorganic-organic composite based on polyvinyl alcohol (PVA) and polysiloxane using the sol-gel disc technique. Antigen obtained from Yersinia pestis was covalently immobilized onto these discs with glutaraldehyde and used as solid phase in ELISA for antibody detection in serum of rabbits experimentally im
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-04