Solid Lipid Nanoparticle
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Lipid core nanoparticles resembling low-density lipoprotein and regression of atherosclerotic lesions: effects of particle size
Particles are usually polydispersed and size is an important feature for lipid-based drug delivery systems in order to optimize cell-particle interactions as to pharmacologic action and toxicity. Lipid nanoparticles (LDE) with composition similar to that of low-density lipoprotein carrying paclitaxel were shown to markedly reduce atherosclerosis lesions indu
Braz J Med Biol Res. Publicado em: 01/03/2018
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2. A simple HPLC method for the determination of halcinonide in lipid nanoparticles: development, validation, encapsulation efficiency, and in vitro drug permeation
ABSTRACT Halcinonide is a high-potency topical glucocorticoid used for skin inflammation treatments that presents toxic systemic effects. A simple and quick analytical method to quantify the amount of halcinonide encapsulated into lipid nanoparticles, such as polymeric lipid-core nanoparticles and solid lipid nanoparticles, was developed and validated regard
Braz. J. Pharm. Sci.. Publicado em: 22/06/2017
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3. Nanoparticles containing curcuminoids (Curcuma longa): development of topical delivery formulation
Solid lipid nanoparticles incorporating Curcuma longa L., Zingiberaceae, curcuminoids were produced by the hot melt emulsion method. A Box–Behnken factorial design was adopted to study the nanoparticles production at different levels of factors such as the percentage of curcuminoids, time of homogenization and surfactant ratio. The optimized nanoparticles
Rev. bras. farmacogn.. Publicado em: 2015-02
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4. Preparação e caracterização de micro e nanopartículas lipídicas sólidas para aplicação em cosméticos / Preparation and caracterization of solid lipid micro and nanoparticles, for application in cosmetics
Neste trabalho, estudou-se o desenvolvimento tecnológico de micro/ nanopartículas lipídicas sólidas para aplicação cosmética capilar. As micropartículas foram produzidas por spray cooling, onde incorporou-se na matriz lipídica, composta por ceras naturais de origem vegetal (cera de carnaúba), mineral (microparafina) e sintética (cera de silicone),
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/07/2011
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5. Development and evaluation of topical formulation containing solid lipid nanoparticles of vitamin A
The purpose of this research was to investigate novel particulate carrier system such as solid lipid nanoparticles (SLN) for topical application of vitamin A palmitate and to study its beneficial effects on skin. Topical gels enriched with SLN of vitamin A were prepared. The solid lipid nanoparticulate dispersion was prepared using high-pressure homogenizati
Springer-Verlag.
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6. Investigations of the effect of the lipid matrix on drug entrapment, in vitro release, and physical stability of olanzapine-loaded solid lipid nanoparticles
The purpose of this research was to study the effect of the lipid matrix on the entrapment of olanzapine (OL). OL-loaded solid lipid nanoparticles (SLNs) were prepared using lipids like glyceryl monostearate (GMS), Precirol ATO 5 (PRE), glyceryl tristearate (GTS), and Witepsol E85 (WE 85)—and poloxamer 407 and hydrogenated soya phosphatidylcholine as stabi
Springer-Verlag.