Snp 49
Mostrando 13-17 de 17 artigos, teses e dissertações.
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13. Polimorfismo N363S do gene do receptor de glucocorticoide: efeito sobre a adiposidade visceral medida pela tomografia computadorizada
OBJETIVO: Verificar se a presença do polimorfismo N363S do gene do receptor de glucocorticoide estaria associada, em indivíduos obesos, à presença de adiposidade visceral pela tomografia computadorizada, e sobre o impacto desta variante genética no perfil metabólico. MÉTODOS: A variante N363S do receptor do glicocorticoide foi verificada em um grupo d
Arq Bras Endocrinol Metab. Publicado em: 2009-03
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14. Análise de polimorfismo no gene CTLA-4 em pacientes com paracoccidioidomicose
The CTLA-4 protein is mainly expressed in activated T cells and plays an essential role in the immune response through its regulatory effect on T cell activation. This activity is mediated by the binding of CTLA-4 to molecules of the B7 family that are expressed by antigen-presenting cells. Polymorphisms of the CTLA-4 gene have been correlated to several aut
Publicado em: 2008
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15. Cytotoxic T-Lymphocyte Antigen 4 Gene and Recovery from Hepatitis B Virus Infection
Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is an inhibitory T-cell receptor expressed by activated and regulatory T cells. We hypothesized that single-nucleotide polymorphisms (SNPs) in the gene encoding CTLA-4 may affect the vigor of the T-cell response to hepatitis B virus (HBV) infection, thus influencing viral persistence. To test this hypothesis, we geno
American Society for Microbiology.
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16. Association of chromosome 8q variants with prostate cancer risk in Caucasian and Hispanic men
Genotyping of a 615 kb region within 8q24 with 49 haplotype-tagged single-nucleotide polymorphisms (SNPs) in 2109 samples (797 cases and 1312 controls) of two ethnic/racial groups found SNPs that are significantly associated with the risk for prostate cancer (PCa). The highest significance in Caucasian men was found for rs6983267; the AA genotype reduced the
Oxford University Press.
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17. Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk
We systematically investigated the association of 48 SNPS in four vitamin D metabolizing genes [CYP27A1, GC, CYP27B1 and CYP24A1] with serum 25-hydroxyvitamin D [25(OH)D] and 1,25-dihydroxyvitamin D [1,25(OH)2D] levels and the association of these SNPS and an additional 164 SNPS in eight downstream mediators of vitamin D signaling [VDR, RXRA, RXRB, PPAR, NCO
Oxford University Press.