Slos
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Variabilidade espacial de propriedades físicas e químicas de um neossolo flúvico cultivado com cenoura irrigada com água moderamente salina
An experiment has been performed aiming to evaluate the spatial-time variation patterns of soil humidity in an irrigated area in Pesqueira PE. The experiment has been carried out in an irrigated plot with carrot, with duration of 96 days. Two irrigated sectors (1 and 2) with 900 m2 each (30 m x 30 m) have been monitored in the experiment, using microsprinkle
Publicado em: 2007
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2. Smith-Lemli-Opitz syndrome: clinical and biochemical findings in Brazilian patients
Smith-Lemli-Opitz syndrome (SLOS) or RSH syndrome comprises multiple congenital anomalies and mental retardation. The underlying defect is a deficiency in the activity of delta7-sterol reductase, which decreases cholesterol and increases 7-dehydrocholesterol (7-DHC) levels. Our aim was to identify and evaluate the frequency of SLOS manifestations in a group
Genetics and Molecular Biology. Publicado em: 2006
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3. Efeitos do losartan e espironolactona sobre a estrutura e função do coração de ratos espontaneamente hipertensos
Background: The clinical syndrome of heart failure is the final pathway for myriad diseases that affect the heart, mainly ischemic heart disease and hypertension. Left ventricular hypertrophy is accompanied by a structural remodeling that includes myocyte hypertrophy and interstitial fibrosis. These structural abnormalities related to fibrosis lead to increa
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/12/2003
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4. Diagnosis of Smith-Lemli-Opitz syndrome by ultraviolet spectrophotometry
Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive disorder due to an inborn error of cholesterol metabolism, characterized by congenital malformations, dysmorphism of multiple organs, mental retardation and delayed neuropsychomotor development resulting from cholesterol biosynthesis deficiency. A defect in 3ß-hydroxysteroid-delta7-reductase (delta
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-10
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5. Mutations in the Δ7-sterol reductase gene in patients with the Smith–Lemli–Opitz syndrome
The Smith–Lemli–Opitz syndrome (SLOS) is an inborn disorder of sterol metabolism with characteristic congenital malformations and dysmorphias. All patients suffer from mental retardation. Here we identify the SLOS gene as a Δ7-sterol reductase (DHCR7, EC 1.3.1.21) required for the de novo biosynthesis of cholesterol. The human and murine genes were char
The National Academy of Sciences.
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6. Canine Migration Inhibitory Factor: Effect of Corynebacterium parvum Administration
Peripheral blood lymphocytes from dogs sensitized to streptolysin O (SLO) were assayed for migration inhibitory factor (MIF) production by the indirect MIF test, using guinea pig peritoneal exudate cells as the source of macrophages. A specific direct correlation was established between the degree of inhibition of migration and the concentration of SLO-stimu
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7. 7-Dehydrocholesterol–dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome
Smith-Lemli-Opitz/RSH syndrome (SLOS), a relatively common birth-defect mental-retardation syndrome, is caused by mutations in DHCR7, whose product catalyzes an obligate step in cholesterol biosynthesis, the conversion of 7-dehydrocholesterol to cholesterol. A null mutation in the murine Dhcr7 causes an identical biochemical defect to that seen in SLOS, incl
American Society for Clinical Investigation.
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8. Isolation and characterization of chromosomal promoters of Streptococcus salivarius subsp. thermophilus.
A promoter probe vector, pTG244, was constructed with the aim of isolating transcription initiation signals from Streptococcus thermophilus (Streptococcus salivarius subsp. thermophilus). pTG244 is based on the Escherichia coli-streptococcus shuttle vector pTG222, into which the promoterless chloramphenicol acetyltransferase gene of Bacillus pumilus (cat-86)