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Mostrando 1-12 de 442 artigos, teses e dissertações.
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1. Molecular Modeling and Chemical Synthesis of New Safrol Oxime Ether Derivatives
Leishmaniasis, a neglected tropical disease with a high worldwide incidence, is considered a public health issue in Minas Gerais and Brazil, with a high degree of morbidity, not to mention the lack of therapeutic arsenal. The cysteine protease (rCPB2.8) and cyclin dependent kinase (CRK3), important enzymes for the parasite’s feasibility, were the targets c
J. Braz. Chem. Soc.. Publicado em: 2021-07
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2. Obtaining geotechnical parameters from correlations between geophysics and CPT tests in tailings dams
Abstract This article introduces a hassle-free methodology for geotechnical parameters to be obtained from correlations between geophysics and CPT field tests in tailings dams undergoing the decommissioning process, which are reasonably representative of site conditions, from the very early project stages, with extensive coverage of all impoundment parts, wi
REM, Int. Eng. J.. Publicado em: 2020-12
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3. Photoluminescent Investigation of the Doping Site of Eu3+-Doped [Zn3(BTC)2·12H2O] Metal-Organic Framework Prepared by Microwave-Assisted Hydrothermal Synthesis
The [Zn3(BTC)2·12H2O] (BTC = 1,3,5-tricarboxylate) metal-organic framework (MOF) was successfully synthesized using a microwave-assisted hydrothermal synthesis technique, which allowed for significantly decreased reaction time compared to the production of the same compound via conventional heating. In situ doping with Eu3+ ions at concentrations ranging fr
J. Braz. Chem. Soc.. Publicado em: 2020-11
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4. ESTUDOS DE QSAR PARA SARS-CoV-2
The generation of mathematical models through the quantitative relationship between the chemical structure and the biological activity (QSARs) of compounds was used in this investigation. Mathematical models were generated from compounds available in literature that predicting the biological activity against SARS-CoV-2. The data indicate that the parameters
Quím. Nova. Publicado em: 2020-09
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5. An Expedient Synthesis of Tacrine-Squaric Hybrids as Potent, Selective and Dual-Binding Cholinesterase Inhibitors
The restoration of acetylcholine levels in the brain by inhibition of cholinesterases is currently the most successful therapeutic strategy to treat neurodegenerative disorders. In this context, tacrine has been largely investigated as a starting scaffold for the development of promising new anticholinesterases compounds for the treatment of neurodegenerativ
J. Braz. Chem. Soc.. Publicado em: 2020-05
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6. EIF1AX c.338-2A>T splice site mutation in a patient with trabecular adenoma and cytological indeterminate lesion
SUMMARY The EIF1AX gene mutations have been recently associated with papillary thyroid carcinoma and anaplastic thyroid cancer. According with these reports, the gene as been considered as a drive gene for thyroid cancer development. However, the occurrence of these alterations in benign thyroid lesions is not known and is still under investigation. Some aut
Arch. Endocrinol. Metab.. Publicado em: 2020-04
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7. The carrion beetle Oxelytrum discicolle (Coleoptera: Silphidae) and the estimative of the minimum post-mortem interval in a forensic case in Brasília, Brazil
Abstract The order Coleoptera is considered second highest in forensic importance in criminal cases involving violent death, because members of this order increase in richness and abundance as the decomposition process progresses. We present here the first Forensic Entomology (FE) case in Brazil where the carrion beetle, Oxelytrum discicolle (Coleoptera: Sil
Rev. Bras. entomol.. Publicado em: 17/01/2020
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8. Notalgia paresthetica and neuropathic itch. Case report
RESUMO JUSTIFICATIVA E OBJETIVOS: A notalgia parestésica é um distúrbio neuropático sensitivo que acomete a região dorsal entre os dermátomos de T2 a T6, caracterizando-se por uma evolução crônica com períodos de remissão e exacerbação. O objetivo deste relato foi descrever um caso de notalgia parestésica, desde a sua investigação clínica e
BrJP. Publicado em: 02/12/2019
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9. First inventory of benthic mollusks associated with the reef ecosystems of Morro de São Paulo on Tinharé Island in northeastern Brazil
Resumo: Os ecossistemas recifais do Morro de São Paulo estão na área de proteção ambiental Tinharé-Boipeba, a qual foi estabelecida em 1992 no estado da Bahia, Brasil. Apesar desta área ter sido criada há mais de duas décadas, nenhum estudo foi realizado sobre a biodiversidade de invertebrados associados a tais ecossistemas recifais. Este trabalho r
Biota Neotrop.. Publicado em: 10/10/2019
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10. A dinosaur ilium from the Late Triassic of Brazil with comments on key-character supporting Saturnaliinae
Abstract: Discoveries in Carnian-aged rocks are establishing a rich and diverse dinosaurian fauna at the so-called ‘dawn of the age of dinosaurs’ in the Late Triassic of Western Gondwana. Accordingly, Brazilian strata from the Candelária Sequence have contributed extensively to this trend. Here, we present a new dinosaurian specimen (CAPPA/UFSM 0200) fr
An. Acad. Bras. Ciênc.. Publicado em: 08/08/2019
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11. Evaluation of the diagnostic potential of CD1a immunohistochemistry for visceral leishmaniasis
ABSTRACT Visceral Leishmaniasis is a public health problem caused by protozoans of the genus Leishmania. K39 serological test is commonly used in the initial investigation, with high specificity, but variable sensitivity. Amastigotes can be identified by optical microscopy, however, the differential diagnosis with cellular debris or other intracellular paras
Rev. Inst. Med. trop. S. Paulo. Publicado em: 18/04/2019
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12. VIGILÂNCIA POR PISTAS OU RETROSPECTIVA? QUAL O IMPACTO NA NOTIFICAÇÃO DAS INFECÇÕES DO SÍTIO CIRÚRGICO EM CIRURGIA CARDÍACA
RESUMO Objetivo: avaliar o impacto das infecções do sítio cirúrgico notificadas pela vigilância por pistas comparadas àquelas detectadas pela avaliação retrospectiva do prontuário do paciente. Método: estudo epidemiológico e de reflexão conduzido em um hospital de grande porte, público, universitário. Resultados: a coleta dos dados ocorreu p
Texto contexto - enferm.. Publicado em: 31/01/2019