Single Nucleotide Polymorphism
Mostrando 13-24 de 563 artigos, teses e dissertações.
-
13. Association of glutamate metabotropic receptor polymorphisms and sensorineural hearing loss in adults of different age groups
Resumo Introdução: A perda auditiva neurossensorial é um desafio comum no mundo todo, inclui uma parte da população jovem. Embora haja muitos relatos que associem o gene do receptor metabotrópico de glutamato 7 com perda auditiva neurossensorial, não há relato, até a presente data, sobre a associação de polimorfismos do receptor metabotrópico de
Braz. j. otorhinolaryngol.. Publicado em: 07/11/2019
-
14. Cucumber mosaic virus resistance and reproductive biology of brazilian melon accessions
Resumo No meloeiro (Cucumis melo), a resistência ao Cucumber mosaic virus (CMV) e o conhecimento sobre características reprodutivas são importantes para escolha de genitores de populações de melhoramento. Desta forma, objetivou-se verificar se diferentes acessos de meloeiro em um banco de germoplasma brasileiro possuem resistência ao CMV (estirpe FNY)
Rev. Bras. Frutic.. Publicado em: 10/10/2019
-
15. Genetic linkage map and mapping of the locus of biological nitrogen fixation inefficiency in cowpea
ABSTRACT. The objectives of the present study were to construct a cowpea genetic map using the F2 population resulting from the cross IC-1 x BRS Marataoã, based on single nucleotide polymorphism (SNP) markers, and to map the cpi gene, with additional reference to introgression with the consensus map of species, aiming to identify markers for assisted select
Acta Sci., Agron.. Publicado em: 23/09/2019
-
16. Whole-exome sequencing in familial keratoconus: the challenges of a genetically complex disorder
RESUMO Objetivos: As causas genéticas subjacentes do ceratocone são essencialmente desconhecidas. Aqui, realizamos o sequenciamento de todo exoma de duas famílias brasileiras com ceratocone. Métodos: O sequenciamento total do exoma foi realizado em 6 indivíduos com ceratocone de duas famílias distintas do sul do Brasil. Variantes patogênicas foram i
Arq. Bras. Oftalmol.. Publicado em: 29/08/2019
-
17. Association between BDNF G196A (Val66Met) polymorphism and cognitive impairment in patients with Parkinson's disease: a meta-analysis
Brain-derived neurotrophic factor (BDNF) is widely expressed in the central nervous system and prolongs the survival of dopaminergic neurons in the substantia nigra. Several studies have recently investigated the association between BDNF G196A (Val66Met), a single nucleotide polymorphism influencing cognitive processes, and cognitive impairment in Parkinson'
Braz J Med Biol Res. Publicado em: 29/07/2019
-
18. Effects of melanocortin 1 receptor (MC1R) gene polymorphisms on plumage color in mule ducks
ABSTRACT The objective of the present study was to investigate the effect of single nucleotide polymorphism (SNP) of the melanocortin 1 receptor (MC1R) gene on plumage coloration in mule ducks. PCR-high-resolution melting analysis (PCR-HRM) and DNA sequencing were used to identify the SNP variability of the MC1R gene in white common ducks. Three non-synonymo
R. Bras. Zootec.. Publicado em: 22/07/2019
-
19. Identification of duplicates in cassava germplasm banks based on single-nucleotide polymorphisms (SNPs)
ABSTRACT: Genetic redundancy in cassava (Manihot esculenta Crantz) presents a challenge to efficient management of genetic resources. This study aimed to identify and define the genetic structure of duplicates in cassava germplasm from various Embrapa research units, using single-nucleotide polymorphism (SNP) markers. We evaluated 2,371 accessions with 20,71
Sci. agric. (Piracicaba, Braz.). Publicado em: 2019-07
-
20. Impact of CPS1 Gene rs7422339 Polymorphism in Argentine Patients With Hyperhomocysteinemia
Abstract Carbamoyl phosphate synthetase 1 (CPS1) is a key gene in the first step of urea cycle and has been correlated with nitric oxide level and vascular smooth muscle activity. A functional single-nucleotide polymorphism C/A at position 4217 in CPS1 (National Center for Biotechnology Information SNP database no. rs7422339, T1405N) was reported to be assoc
J. inborn errors metab. screen.. Publicado em: 19/06/2019
-
21. Additional information offered by single nucleotide polymorphism array advantages in two myelodysplastic syndromes with excess blasts cases and future perspectives
Hematol., Transfus. Cell Ther.. Publicado em: 10/06/2019
-
22. In silico prediction of the functional and structural consequences of the non-synonymous single nucleotide polymorphism A122V in bovine CXC chemokine receptor type 1
Resumo O presente estudo objetivou avaliar se o polimorfismo causal A122V promove alterações nas propriedades funcionais e estruturais da proteína receptora de quimiocina CXC do tipo 1 (CXCR1) de bovino Bos taurus por análises in silico. Duas sequências de aminoácidos da CXCR1 bovina foram selecionadas a partir do banco de dados UniProtKB/Swiss-Prot:
Braz. J. Biol.. Publicado em: 18/04/2019
-
23. Genotyping of South American clinical isolates of Pythium insidiosum based on single nucleotide polymorphism-based multiplex PCR
RESUMO: O objetivo deste estudo foi genotipar isolados clínicos de Pythium insidiosum da América do Sul utilizando polimorfismos de nucleotídeo único (SNP) de sequências de rDNA. Anteriormente, um multiplex-PCR baseado em SNP foi capaz de distinguir P. insidiosum em três diferentes clados. Dessa forma, utilizamos este método para avaliar isolados cl�
Cienc. Rural. Publicado em: 17/01/2019
-
24. Genetic variation of aggrecanase-2 (ADAMTS5) in susceptibility to osteoarthritis
Aggrecanase-2 (ADAMTS5) gene is responsible for aggrecan degradation that may contribute to cartilage destruction in a mouse osteoarthritis (OA) model. We aimed to investigate the effects of ADAMTS5 gene polymorphisms on OA risk in a Chinese population. A total of 300 OA patients and 300 controls were recruited and their genotypes for ADAMTS5 gene rs226794 a
Braz J Med Biol Res. Publicado em: 10/01/2019