Simplex Method
Mostrando 1-12 de 251 artigos, teses e dissertações.
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1. ASSESSMENT OF α-AMYLASE INHIBITION ACTIVITY BY AN OPTIMIZED AND VALIDATED IN VITRO MICROSCALE METHOD
Metabolic disorders, including hyperglycemia, characterize type-2 diabetes. One of the treatment methods used for postprandial hyperglycemia includes using potential therapeutic agents to inhibit α-amylase activity. This study utilized fractional design and the simplex method to optimize in vitro microscale assay inhibition conditions using Miller’s react
Química Nova. Publicado em: 2022
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2. Simultaneous Transfer of Na+, K+, and Fe2+ Ions During Salting of Precooked Mushroom (Agaricus bisporus): Mathematical Modeling, Optimization, and Experimental Validation
The champignon mushroom has no antinutritional factors that can affect iron bioavailability. It is considered a functional food and can provide health benefits by presenting bioactive components. The simultaneous transfer of Na+, K+ and Fe2+ in the pre-cooked mushroom (Agaricus bisporus) was modeled and simulated by the finite element method (FEM). The Biot
J. Braz. Chem. Soc.. Publicado em: 2020-06
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3. Mathematical Modeling of the Transesterification Reaction by Finite Elements: Optimization of Kinetic Parameters Using the Simplex Sequential Method
The use of biodiesel as fuel has been presented as a viable alternative in the search for renewable energies. It can be produced from the transesterification reaction of vegetable oils with methanol in the presence of sodium or potassium hydroxide as catalysts. In the present research, the transesterification reaction of soybean oil was modeled considering t
J. Braz. Chem. Soc.. Publicado em: 2020-02
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4. Optimized dimensioning of steel-concrete composite beams
Resumo As seções mistas de aço e concreto estão cada vez mais sendo utilizadas na construção civil, tanto no cenário mundial quanto no Brasil. O trabalho conjunto do perfil de aço e da laje de concreto aumenta consideravelmente o desempenho do elemento estrutural misto devido ao aproveitamento das vantagens de cada material. Neste trabalho, é utiliz
Rev. IBRACON Estrut. Mater.. Publicado em: 13/12/2019
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5. Biological activities of marine invertebrates extracts from the northeast brazilian coast
Resumo Este artigo reporta as atividades in vitro antiproliferativa, atiprotozoárica, anti-herpética e antimicrobiana de 32 extratos orgânicos provenientes de 14 esponjas marinhas e 14 corais coletados no litoral nordestino brasileiro. Os extratos etanólicos das esponjas Amphimedon compressa e Tedania ignis, e o extrato acetônico de Dysidea sp. demonstr
Braz. J. Biol.. Publicado em: 05/08/2019
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6. Optimizing the Extraction of Anthocyanins from the Skin and Phenolic Compounds from the Seed of Jabuticaba Fruits (Myrciaria jabuticaba (Vell.) O. Berg) with Ternary Mixture Experimental Designs
Total phenolic compounds (TPC) extraction from the seed and total monomeric anthocyanins (TMA) extraction from the skin of “Sabará” jabuticaba were optimized with simplex lattice designs for solvent mixing, and the extraction time was optimized by univariate design. The optimum conditions for the extraction method were ethanol:water (60:40 v/v) solvent
J. Braz. Chem. Soc.. Publicado em: 04/07/2019
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7. Optimization of reinforced concrete polygonal sections under biaxial bending with axial force
Abstract Concrete is the world’s most utilized material for production of the structural elements employed in civil construction. Due to its low tensile strength and brittle nature it is reinforced with steel bars forming the reinforced concrete (RC structure). Linear elements of reinforced concrete are commonly employed in multi-story buildings, bridges,
Lat. Am. j. solids struct.. Publicado em: 04/10/2018
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8. Jambolan sherbets overrun, color, and acceptance in relation to the sugar, milk, and pulp contents in formulation
Abstract The aim of this study was to evaluate in sherbet formation the effects of sugar, milk, and jambolan pulp quantity on the overrun, color, physicochemical characteristics, microbiological characteristics, and acceptance of the experimental sherbets, in addition to evaluating the bioactive compounds of the selected product. Seven formulations were est
Food Sci. Technol. Publicado em: 07/05/2018
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9. Determination of Chlorine in Crude Oil Emulsified via the MgCl Molecule by HR-CS MAS
A method for chlorine determination in crude oil samples, through the formation of MgCl molecule, by high-resolution continuum source graphite furnace molecular absorption spectrometry (HR-CS GF MAS) was developed and is described in this paper. The use of this molecule for chlorine determination in crude oil has not been reported up to now. Measures were ca
J. Braz. Chem. Soc.. Publicado em: 2018-03
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10. In vitro evaluation of cutaneous penetration of acyclovir from semisolid commercial formulations and relation with its effective antiviral concentration
ABSTRACT The evaluation of drug permeation/penetration of semisolid formulations into animal skin can be useful to supplement the pharmaceutical equivalence. This paper describes the in vitro assessment of acyclovir (ACV) into porcine skin from commercial formulations with etermination of drug concentration in different layers of cutaneous tissue to correlat
Braz. J. Pharm. Sci.. Publicado em: 2016-09
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11. Synthesis Optimization of MCM-41 for CO2 Adsorption Using Simplex-centroid Design
There is a growing concern on the relationship between anthropogenic carbon dioxide and climate changes. A promising approach is the adsorption technology using mesoporous MCM-41 materials that can be easily synthesized to depict structures adequate to the flow of gas. The aim of this study was to improve the synthesis of MCM-41 using cationic surfactant mix
Mat. Res.. Publicado em: 2015-08
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12. Cytotoxic activity of marine algae against cancerous cells
This paper presents an investigation on the cytotoxic activity in human tumor cell from dichloromethane, chloroform, methanol, ethanol, water extracts, and hexane and chloroform fractions from green, brown and red algae collected at Riacho Doce Beach, north coast of Alagoas, Brazil, against the cancer cells K562 (chronic myelocytic leukemia), HEp-2 (laryngea
Rev. bras. farmacogn.. Publicado em: 13/09/2013