Simian Malaria
Mostrando 1-12 de 21 artigos, teses e dissertações.
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1. Plasmodium simium/Plasmodium vivax infections in southern brown howler monkeys from the Atlantic Forest
Blood infection by the simian parasite, Plasmodium simium, was identified in captive (n = 45, 4.4%) and in wild Alouatta clamitans monkeys (n = 20, 35%) from the Atlantic Forest of southern Brazil. A single malaria infection was symptomatic and the monkey presented clinical and haematological alterations. A high frequency of Plasmodium vivax-specific antibod
Mem. Inst. Oswaldo Cruz. Publicado em: 05/08/2014
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2. Detecção dos agentes etiológicos da malária em símios resgatados em regiões de Mata Atlântica de São Paulo / Detection of etiological agents of malaria in monkeys rescued in Atlantic Forest regions of São Paulo
Foram analisadas, para a detecção de plasmódios, 50 amostras de sangue de bugios (Alouatta guariba clamitans) resgatados de várias áreas circundadas pela Mata Atlântica, pertencentes à região metropolitana da cidade de São Paulo. Para tanto, 20 e 30 amostras das regiões de resgate norte e sul respectivamente, foram analisadas pelas técnicas de mic
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/04/2011
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3. Analyze of molecular differentiation among Anopheles (Kerteszia) cruzi Brazilian populations using a multilocus approach (Diptera: Culicidae) / Análise da diferenciação molecular entre populações brasileiras de Anopheles (Kerteszia) cruzii utilizando uma abordagem multilocus (Diptera: Culicidae)
Anopheles (Kerteszia) cruzii (Diptera: Culicidae) has long been known as the primary vector of human and simian malaria parasites in southern and southeastern Brazil. The distribution of this mosquito follows the coast of the Brazilian Atlantic forest. Previous studies have suggested that An. cruzii is a complex of cryptic species. In the current study, a fr
Publicado em: 2009
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4. Caracterização epidemiológica da malária autóctone do Espírito Santo / Study of the epidemiologic aspects of the indigenous malaria in Espírito Santo State
The several aspects of the transmission cycle of the indigenous malaria are important to base on the intervention strategies. From April 2001 to March 2004, 65 patients and 1,777 inhabitants were evaluated in nine Municipalities of the highlands of Espírito Santo State. Laboratory methods included: thick and thin smears, Multiplex PCR, imunnofluorescent ass
Publicado em: 2007
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5. Time course of in vitro maturation of intra-erythrocytic malaria parasite: a comparison between Plasmodium falciparum and Plasmodium knowlesi
The schizont maturation assay for in vitro drug sensitivity tests has been a standard method employed in the global baseline assessment and monitoring of drug response in Plasmodium falciparum. This test is limited in its application to synchronous plasmodial infections because it evaluates the effect of drug on the maturation of parasite especially from rin
Memórias do Instituto Oswaldo Cruz. Publicado em: 2002-09
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6. Variants of the Plasmodium vivax circumsporozoite protein (VK210 and VK247) in Colombian isolates
Phenotypic diversity has been described in the central repeated region of the circumsporozoite protein (CSP) from Plasmodium vivax. Two sequences VK210 (common) and VK247 (variant) have been found widely distributed in P. vivax isolates from several malaria endemic areas around the world. A third protein variant called P. vivax-like showing a sequence simila
Memórias do Instituto Oswaldo Cruz. Publicado em: 2001-07
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7. Monoclonal antibodies to the circumsporozoite protein repeats of a Plasmodium vivax-like human malaria parasite and Plasmodium simiovale.
We have recently described a Plasmodium vivax-like human malaria parasite. The circumsporozoite protein of this parasite is identical to that of a simian malaria parasite, P. simiovale, but different from two known types of P. vivax. Here, we describe the production of two monoclonal antibodies, Pam 172 and Pam 135, specific for the circumsporozoite protein
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8. THE EFFECT OF FATAL P. KNOWLESI MALARIA ON SIMIAN CIRCULATORY AND BODY FLUID COMPARTMENT PHYSIOLOGY 1
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9. Man, monkeys and malaria.
Bizarre though it may now seem, in the last century a whole series of experiments was conducted that involved injecting fresh monkey blood into human volunteers or patients. The reasons, valid at the time, were either to treat neurosyphilis with a relatively benign simian malaria infection (so-called pyrogen therapy), or to establish which monkey malaria spe
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10. Monoclonal antibodies identify the protective antigens of sporozoites of Plasmodium knowlesi.
Nine monoclonal antibodies against surface antigens of sporozoites of the simian malaria parasite Plasmodium knowlesi were produced by fusion of plasmacytoma cells with spleen cells of a mouse immunized with the parasites. Immunoprecipitation of extracts of [35S]methionine-labeled sporozoites with seven of the monoclonals identified the same three polypeptid
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11. Recombinant human gamma interferon inhibits simian malaria.
Prophylactic treatment with 0.1 mg of human gamma interferon per kg (body weight) per day completely suppressed experimental infection with Plasmodium cynomolgi B sporozoites in rhesus monkeys. Treatment with lower doses partially suppressed this infection. Prophylactic treatment with human gamma interferon, however, had no protective effect against trophozo
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12. The unusually large Plasmodium telomerase reverse-transcriptase localizes in a discrete compartment associated with the nucleolus
Telomerase replicates chromosome ends, a function necessary for maintaining genome integrity. We have identified the gene that encodes the catalytic reverse transcriptase (RT) component of this enzyme in the malaria parasite Plasmodium falciparum (PfTERT) as well as the orthologous genes from two rodent and one simian malaria species. PfTERT is predicted to
Oxford University Press.