Short Tandem Repeat
Mostrando 1-12 de 135 artigos, teses e dissertações.
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1. Quantification of mixed chimerism allows early therapeutic interventions
Hematopoietic stem cell transplantation is the curative option for patients with myelodysplastic syndrome; however, it requires a long post-transplantation follow-up. A 53-year-old woman with a diagnosis of myelodysplastic syndrome underwent related donor allogeneic hematopoietic stem cell transplantation in July 2006. Three months after transplantation, a c
Rev. Bras. Hematol. Hemoter.. Publicado em: 2014-10
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2. Frequência alélica de sete marcadores Short Tandem Repeat em indivíduos do estado do Rio Grande do Sul, Brasil
Dados populacionais de sete loci Short Tandem Repeat do kit comercial PowerPlex CS7 foram obtidos a partir de uma amostra de 401 indivíduos do Rio Grande do Sul (sul do Brasil). Os loci são os dois pentanucleotídeos STRs do PowerPlex 16 (PENTA D e PENTA E), um pentanucleotídeo extra (PENTA C), além dos quatro loci STR do kit comercial FFFL Fluorescent S
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/03/2012
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3. Genomic instability at the 13q31 locus and somatic mtDNA mutation in the D-loop site correlate with tumor aggressiveness in sporadic Brazilian breast cancer cases
OBJECTIVE: Genomic instability is a hallmark of malignant tissues. In this work, we aimed to characterize nuclear and mitochondrial instabilities by determining short tandem repeats and somatic mitochondrial mutations, respectively, in a cohort of Brazilian sporadic breast cancer cases. Furthermore, we performed an association analysis of the molecular findi
Clinics. Publicado em: 2012-10
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4. Association of MICA gene polymorphisms with liver fibrosis in schistosomiasis patients in the Dongting Lake region
Major histocompatibility complex class I chain-related A (MICA) is a highly polymorphic gene located within the MHC class I region of the human genome. Expressed as a cell surface glycoprotein, MICA modulates immune surveillance by binding to its cognate receptor on natural killer cells, NKG2D, and its genetic polymorphisms have been recently associated with
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-03
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5. Allelic frequencies and statistical data obtained from 12 codis STR loci in an admixed population of the Brazilian Amazon
The allelic frequencies of 12 short tandem repeat loci were obtained from a sample of 307 unrelated individuals living in Macapá, a city in the northern Amazon region, Brazil. These loci are the most commonly used in forensics and paternity testing. Based on the allele frequency obtained for the population of Macapá, we estimated an interethnic admixture f
Genetics and Molecular Biology. Publicado em: 2011
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6. Short-tandem repeat analysis in seven Chinese regional populations
In the present study, we investigated the application of 13 short tandem repeat (STR) loci (D13S317, D7S820, TH01, D16S539, CSFIPO, VWA, D8S1179, TPOX, FGA, D3S1358, D21S11, D18S51 and D5S818) routinely used in forensic analysis, for delineating population relationships among seven human populations representing the two major geographic groups, namely the so
Genetics and Molecular Biology. Publicado em: 2010
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7. Analysis of 31 STR loci in the genetic isolate of Carloforte (Sardinia, Italy)
The genotypes of 31 autosomal short tandem repeat loci in the population of Carloforte were analyzed, these representing a linguistic and genetic isolate located on the island of Sardinia (Italy). The markers span the entire length of chromosomes 19, 20, 21 and 22. Allele frequencies and statistical parameters were presented for all loci. Observed heterozygo
Genetics and Molecular Biology. Publicado em: 03/07/2009
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8. Um novo modelo para cálculo de probabilidade de paternidade - concepção e implementação / A Novel Model for Paternity Probability Calculation - Design and Implementation
Nesta tese são apresentados um novo modelo estatístico para cálculo de probabilidade de paternidade e sua implementação em software. O modelo proposto utiliza o genótipo como informação básica, em contraste com outros modelos que usam alelos. Por esta diferença, o modelo proposto resulta mais abrangente, mas que, sob certas restrições, reproduz o
Publicado em: 2006
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9. Y-STR diversity and ethnic admixture in White and Mulatto Brazilian population samples
We investigated 50 Mulatto and 120 White Brazilians for the Y-chromosome short tandem repeat (Y-STR) markers (DYS19, DYS390, DYS391, DYS392 and DYS393) and found 79 different haplotypes in the White and 35 in the Mulatto sample. Admixture estimates based on allele frequencies showed that the admixture of the white sample was 89% European, 6% African and 5% A
Genetics and Molecular Biology. Publicado em: 2006
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10. Microsatellite studies on an isolated population of African descent in the Brazilian state of Bahia
The African descent population of the Bananal community in the Brazilian state of Bahia (BA) was characterized as a genetic isolate and analyzed for some short tandem repeat (STR) microsatellite autosomic polymorphic loci (CSF1PO, TH01, TPOX, F13A1, FESFPS and vWA). These genetic variants were further compared to data obtained from an urban sample from the t
Genetics and Molecular Biology. Publicado em: 2006
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11. DeterminaÃÃo do polimorfismo e anÃlise de 5 marcadores do cromossomo Y em Pernambuco
We present a Y-chromosome short tandem repeat (STR)-haplotype database consisting of the loci DYS19, DYS390, DYS391, DYS392 and DYS393. Short tandem repeat (STR) polymorphism from male specific part of the Y-chromosome are increasingly being used for the study of male specific lineage evolution as well as for forensic applications. The most frequent alleles
Publicado em: 2003
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12. Microsatellite instability and cytogenetic survey in myeloid leukemias
Microsatellites are short tandem repeat sequences dispersed throughout the genome. Their instability at multiple genetic loci may result from mismatch repair errors and it occurs in hereditary nonpolyposis colorectal cancer. This instability is also found in many sporadic cancers. In order to evaluate the importance of this process in myeloid leukemias, we s
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-02