Sesquiterpene Lactones
Mostrando 1-12 de 38 artigos, teses e dissertações.
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1. Isolation and characterization of sesquiterpene lactones from Calea uniflora Less. and their leishmanicidal and trypanocidal activities
Calea uniflora Less., commonly known in Brazil as “erva-de-lagarto” and “arnica-da-praia”, is used in folk medicine to treat internal and external bruises and as anti-inflammatory. However, despite the popular use there is a lack of information in terms of isolation and biological evaluation of its secondary metabolites. Thus, the aims of this study
Quím. Nova. Publicado em: 2021-06
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2. Mango (Mangifera indica) Aroma Discriminate Cultivars and Ripeness Stages
Mango (Mangifera indica) has many nutritional attributes that stimulate its consumption, such as sweetness, balanced acidity and intense fruity aroma. In this study, it was demonstrated that both the variety and ripening stage have a significant impact on the aroma of mango. The volatile compound profile of “Tommy Atkins”, “palmer”, “espada” and
J. Braz. Chem. Soc.. Publicado em: 2020-07
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3. Relationship Between Parameters of Development and Functional Compounds of Yacon Leaves
Abstract Yacon is a tuberous root from the Andean region being increasingly grown across the world due to the low caloric values of their roots and the functional properties of extractions of its leaves. However, there is still a gap in the knowledge of how the plant develops, and if physical and chemical changes are noticed regarding maturity. The subject o
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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4. “Arnicas” from Brazil: comparative analysis among ten species
Abstract The “arnicas” found in Brazil are examples of different species of the family Asteraceae used in popular medicine for its attributed anti-inflammatory action. Among the species known and used as “arnica” we selected: Calea uniflora Less., Chaptalia nutans (L.) Polák, Lychnophora ericoides Mart., Lychnophora pinaster Mart., Lychnophora salic
Rev. bras. farmacogn.. Publicado em: 17/10/2019
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5. Chemical Constituents, Antiproliferative and Antioxidant Activities of Vernonanthura nudiflora (Less.) H. Rob. Aerial Parts
Sesquiterpene lactones are an important class of secondary metabolites frequently isolated from Vernonanthura genus that present a variety of biological properties, including antiproliferative activity. Due to the limitation of pharmacological studies on Vernonanthura nudiflora, the aim of this work was to investigate their antioxidant potential and antiprol
J. Braz. Chem. Soc.. Publicado em: 12/08/2019
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6. In vivo anti-hyperuricemic activity of sesquiterpene lactones from Lychnophora species
ABSTRACT Hyperuricemia is the main cause of gout, an inflammation induced by uric acid deposition in joints. Drugs available present side effects, so there is a need for new treatment alternatives. Lychnophora species are used in folk medicine to treat inflammation, rheumatism and muscle pain. Goyazensolide (10 mg/kg), eremantholide C (25 mg/kg) and lychnoph
Rev. bras. farmacogn.. Publicado em: 27/05/2019
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7. Sesquiterpene lactones from Hedyosmum brasiliense induce in vitro relaxation of rat aorta and corpus cavernosum
Abstract Hedyosmum brasiliense Miq., Chloranthaceae, has been used in Southern Brazil as a sedative, anti-inflammatory, and aphrodisiac. In this study, endothelium-intact and endothelium-denuded rat aortic rings and strips of corpus cavernosum were used to investigate the relaxant effects of an hexane fraction of leaves of H. brasiliense and its sesquiterpen
Rev. bras. farmacogn.. Publicado em: 2016-06
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8. Effects of budlein A on human neutrophils and lymphocytes
ABSTRACT Sesquiterpene lactones (SLs) are the active constituents of a variety of medicinal plants used in traditional medicine for the treatment of inflammatory diseases and other ailments. Objective In this study, we evaluated whether budlein A modulates the activation of innate and adaptive immune cells such as neutrophils and lymphocytes. Material and
J. Appl. Oral Sci.. Publicado em: 2016-06
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9. Cytotoxic sesquiterpene lactones from the aerial parts of Inula aucheriana.
Inula aucheriana DC, uma espécie da família Asteraceae, é conhecida pela produção de lactonas sesquiterpênicas que são metabólitos secundários cititóxicos. No presente estudo, as seguintes lactonas sesquiterpênicas foram isoladas de I. aucheriana: inuchinenolida B, 6-desoxichamissonolida (estevina) e 14-acetoxi-1β,5α,7αH-4β-hidroxi-guai-9(10,
An. Acad. Bras. Ciênc.. Publicado em: 08/05/2015
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10. Anti-inflammatory sesquiterpene lactones from Tithonia diversifolia trigger different effects on human neutrophils
Abstract The tagitinins isolated of Tithonia diversifolia (Hemsl.) A. Gray, Asteraceae, are the most studied sesquiterpene lactones due to their wide spectrum of pharmacologic activities, especially related with nuclear factor-kappa B inhibition. Nevertheless, detailed studies about the mechanism of action of its active compounds are still lacking. Neutrophi
Rev. bras. farmacogn.. Publicado em: 2015-04
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11. Topical anti-inflammatory activity of yacon leaf extracts
Smallanthus sonchifolius (Poepp.) H. Rob. , Asteraceae, known as yacon, is an herb that is traditionally used for the treatment of diabetes in folk medicine. However, recent studies have demonstrated that this plant has other interesting properties such as anti-microbial and anti-inflammatory actions. Thus, the purpose of this study was to evaluate the topic
Rev. bras. farmacogn.. Publicado em: 10/05/2013
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12. Antiproliferative activity of Eremanthus crotonoides extracts and centratherin demonstrated in brain tumor cell lines
The genus Eremanthus is recognized by the predominance of sesquiterpene lactones from the furanoheliangolide type, a class of substances extensively tested against cancer cell lines. Thus, the species E. crotonoides (DC.) Sch. Bip., Asteraceae, obtained on "restinga" vegetation was evaluated against U251 and U87-MG glioma cell lines using the MTT colorimetri
Rev. bras. farmacogn.. Publicado em: 16/11/2012