Serum Proteome
Mostrando 1-11 de 11 artigos, teses e dissertações.
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1. Proteomic research and diagnosis in bladder cancer: state of the art review
ABSTRACT Purpose: Proteomic biomarkers have been emerging as alternative methods to the gold standard procedures of cystoscopy and urine cytology in the diagnosis and surveillance of bladder cancer (BC). This review aims to update the state of the art of proteomics research and diagnosis in BC. Materials and Methods: We reviewed the current literature rela
Int. braz j urol.. Publicado em: 2021-06
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2. Perfil bioquímico e proteômico do recém nascido pequeno para a idade gestacional: pesquisa de biomarcadores para hipertensão arterial na vida adulta. / Biochemical and proteomic profile of newborns small for gestational age: search for biomarkers for hypertension in adulthood.
Introduction: systemic arterial hypertension is a serious public health problem. A strong correlation between birthweight and mortality and morbidity from hypertension and cardiovascular disease formed the basis for the fetal programming hypothesis for the non communicable diseases of adulthood; also known as Barkers hypothesis of hypothesis of the developme
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/03/2011
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3. Analise proteomica de soro de ratos em diferentes situações de exercicio e uma experiencia de pesquisa em ensino / Serum proteomic analysis of rats in differents exercise situations and an experience in teaching
The adaptive response to a training program is related to an intensive process of protein synthesis, which cumulative effect of multiple sessions of exercise leads to muscle phenotypic alterations and increases different physical capacities. For such adaptation an appropriate time for recovery between stimuli is required. A continuous process of intensified
Publicado em: 2009
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4. Análise proteômica em urina e rim de ratos submetidos a tratamento crônico com flúor / Proteomic analysis of urine kidney in fluoride-treated rat
Two-dimensional gel electrophoresis (2D-PAGE) based proteomics approach was used to better understand the molecular mechanisms of renal injury induced by fluoride (F) and define potentials biomarkers of fluorosis. Three groups of weanling male Wistar rats (21 days old) were treated with drinking water containing 0 (control), 5, or 50 ppm F for 60 days (n=6/g
Publicado em: 2008
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5. Identification of proteins from honeybee venom (Apis mellifera L.) immunoreactives to antivenom serum through a proteomic approach / Identificação das proteínas do veneno de abelhas africanizadas (Apis mellifera L.) imunoreativas ao soro antiveneno por abordagem proteômica
O estudo de venenos de artrópodes é de grande interesse para melhorar os tratamentos contra envenenamentos e oferece uma ótima ferramenta para melhor compreensão dos sistemas nervoso e imunológico, coagulação sanguínea e respostas inflamatórias. As abelhas são um dos animais venenosos mais estudados e a elucidação do seu proteoma é de interesse
Publicado em: 2008
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6. Identification of Novel Serological Biomarkers for Inflammatory Bowel Disease Using Escherichia coli Proteome Chip*
Specific antimicrobial antibodies present in the sera of patients with inflammatory bowel disease (IBD) have been proven to be valuable serological biomarkers for diagnosis/prognosis of the disease. Herein we describe the use of a whole Escherichia coli proteome microarray as a novel high throughput proteomics approach to screen and identify new serological
The American Society for Biochemistry and Molecular Biology.
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7. Profiling the humoral immune response to infection by using proteome microarrays: High-throughput vaccine and diagnostic antigen discovery
Despite the increasing availability of genome sequences from many human pathogens, the production of complete proteomes remains at a bottleneck. To address this need, a high-throughput PCR recombination cloning and expression platform has been developed that allows hundreds of genes to be batch-processed by using ordinary laboratory procedures without roboti
National Academy of Sciences.
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8. Proteomic Analysis of Rickettsia parkeri Strain Portsmouth▿
Rickettsia parkeri, a recently recognized pathogen of human, is one of several Rickettsia spp. in the United States that causes a spotted fever rickettsiosis. To gain insights into its biology and pathogenesis, we applied the proteomics approach to establish a two-dimensional gel proteome reference map and combined this technique with cell surface biotinylat
American Society for Microbiology (ASM).
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9. Drusen proteome analysis: An approach to the etiology of age-related macular degeneration
Drusen are extracellular deposits that accumulate below the retinal pigment epithelium on Bruch's membrane and are risk factors for developing age-related macular degeneration (AMD). The progression of AMD might be slowed or halted if the formation of drusen could be modulated. To work toward a molecular understanding of drusen formation, we have developed a
National Academy of Sciences.
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10. SELDI ProteinChip® Array Technology: Protein-Based Predictive Medicine and Drug Discovery Applications
Predictive medicine, utilizing the ProteinChip® Array technology, will develop through the implementation of novel biomarkers and multimarker patterns for detecting disease, determining patient prognosis, monitoring drug effects such as efficacy or toxicity, and for defining treatment options. These biomarkers may also serve as novel protein drug candidates
Hindawi Publishing Corporation.
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11. The Mycobacterium tuberculosis Complex-Restricted Gene cfp32 Encodes an Expressed Protein That Is Detectable in Tuberculosis Patients and Is Positively Correlated with Pulmonary Interleukin-10
Human tuberculosis (TB) is caused by the bacillus Mycobacterium tuberculosis, a subspecies of the M. tuberculosis complex (MTC) of mycobacteria. Postgenomic dissection of the M. tuberculosis proteome is ongoing and critical to furthering our understanding of factors mediating M. tuberculosis pathobiology. Towards this end, a 32-kDa putative glyoxalase in the
American Society for Microbiology.