Sertraline
Mostrando 1-12 de 34 artigos, teses e dissertações.
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1. The Effect of Neuromodulatory Drugs on the Intensity of Chronic Pelvic Pain in Women: A Systematic Review
Resumo Objetivo: Avaliar o efeito de drogas neuromoduladoras na intensidade da dor pélvica crônica em mulheres. Fontes de dados: As buscas foram realizadas nas bases de dados PubMed, Cochrane Central, Embase, Lilacs, OpenGrey e Clinical Trials. Seleção dos estudos: As buscas foram realizadas por dois dos autores, não delimitando data de publicação
Revista Brasileira de Ginecologia e Obstetrícia. Publicado em: 2022
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2. Which of available selective serotonin reuptake inhibitors (SSRIs) is more effective in treatment of premature ejaculation? A randomized clinical trial
ABSTRACT Purpose: To compare the efficacy and safety of available selective serotonin reuptake inhibitors (SSRIs) in order to find the most effective drug with the least number of side effects in treatment of premature ejaculation (PE). Materials and Methods: This study was a randomized clinical trial. Four hundred and eighty patients with PE in the 4 grou
Int. braz j urol.. Publicado em: 20/12/2019
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3. Effects of sertraline in the prevention of low blood pressure in patients undergoing hemodialysis
Resumo Introdução: A hipotensão intradialítica (HID) é uma das principais complicações da hemodiálise, com uma prevalência de cerca de 25% durante as sessões de hemodiálise, causando aumento da morbimortalidade. Objetivo: Estudar os efeitos da sertralina na prevenção da HID em pacientes em hemodiálise. Métodos: Este foi um ensaio clínico d
J. Bras. Nefrol.. Publicado em: 01/08/2019
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4. Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study
Abstract Background: Drug repurposing has been an interesting and cost-effective approach, especially for neglected diseases, such as Chagas disease. Methods: In this work, we studied the activity of the antidepressant drug sertraline against Trypanosoma cruzi trypomastigotes and intracellular amastigotes of the Y and Tulahuen strains, and investigated its
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 29/11/2018
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5. Development of self-nanoemulsifying tablet (SNET) for bioavailability enhancement of sertraline
Abstract The purpose of the study was to combine the advantages of self-nanoemulsifying drug delivery systems and tablets as a conventional dosage form. Self-nanoemulsifying drug delivery system (SNEDDS) was prepared to enhance the solubility and thus oral bioavailability of sertraline. Aqueous titration method was used to prepare the liquid SNEDDS; ternary
Braz. J. Pharm. Sci.. Publicado em: 07/06/2018
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6. Selective serotonin reuptake inhibitors for fibromyalgia syndrome
ABSTRACT BACKGROUND: Fibromyalgia is a clinically well-defined chronic condition with a biopsychosocial aetiology. Fibromyalgia is characterized by chronic widespread musculoskeletal pain, sleep problems, cognitive dysfunction, and fatigue. Patients often report high disability levels and poor quality of life. Since there is no specific treatment that alte
Sao Paulo Med. J.. Publicado em: 2015-10
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7. Effects of acute administration of selective serotonin reuptake inhibitors on sympathetic nerve activity
Serotonergic mechanisms have an important function in the central control of circulation. Here, the acute effects of three selective serotonin (5-HT) reuptake inhibitors (SSRIs) on autonomic and cardiorespiratory variables were measured in rats. Although SSRIs require 2-3 weeks to achieve their full antidepressant effects, it has been shown that they cause a
Braz J Med Biol Res. Publicado em: 30/05/2014
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8. The effect of Sertraline, Paroxetine, Fluoxetine and Escitalopram on testicular tissue and oxidative stress parameters in rats
Introduction: The aim of this study was to evaluate the effect of selective serotonin reuptake inhibitors (SSRIs) on testicular tissue and serum malondialdehyde (MDA) levels in rats. Materials and methods: A total of 40 male Wistar albino rats, 5.5-6 months old, were equally divided at random into five groups: group 1 was the control group, group 2 receiv
Int. braz j urol.. Publicado em: 2014-01
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9. Investigation of the interaction of sertraline with calf thymus DNA by spectroscopic methods
A interação entre a droga anti-depressiva, sertralina, com o DNA de fita dupla (dsDNA) de timo de vitelo em tampão fisiológico (pH 7,4) foi determinada por espectrofotometria de UV-Vis, espectrofluorimetria, dicroísmo circular, espectroscopia no infravermelho com transformada de Fourier (FTIR), medições da viscosidade e estudos de fusão de DNA. Os es
J. Braz. Chem. Soc.. Publicado em: 2013-06
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10. Serotonina e glicogênio sintase quinase 3B em plaqueta de pacientes idosos com transtorno depressivo maior: efeito do tratamento com sertralina / Serotonin and glycogen synthase kinase 3B in platelets of elderly patients with major depressive disorder: sertraline effects
A depressão é o mais comum dos distúrbios afetivos. Afeta ao menos 10% da população idosa do Brasil. Nos idosos, alguns fatores ligados ao metabolismo parecem estar bastante relacionados a esse transtorno, como uma menor concentração de noradrenalina e serotonina (5-HT) e uma maior atividade da monoaminooxidase em relação a adultos jovens. Os inibid
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2012
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11. Synthesis by precipitation polymerization of a molecularly imprinted polymer membrane for the potentiometric determination of sertraline in tablets and biological fluids
Um quimiossensor potenciométrico para determinação seletiva de sertralina foi desenvolvido, baseado na técnica de impressão molecular. O polímero impresso molecularmente foi sintetizado através da polimerização por precipitação, usando hidrocloreto de sertralina como molécula molde, ácido metacrílico como monômero funcional e dimetacrilato de
Journal of the Brazilian Chemical Society. Publicado em: 2012-03
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12. Sertraline inhibits formalin-induced nociception and cardiovascular responses
The objective of the present study was to determine the antihyperalgesic effect of sertraline, measured indirectly by the changes of sciatic afferent nerve activity, and its effects on cardiorespiratory parameters, using the model of formalin-induced inflammatory nociception in anesthetized rats. Serum serotonin (5-HT) levels were measured in order to test t
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-01