Serotonergic System
Mostrando 1-12 de 72 artigos, teses e dissertações.
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1. Lower limb muscle strength and serotonin receptor gene polymorphism as factors associated in women with fibromyalgia
Abstract Background: Fibromyalgia (FM) is a chronic pain syndrome characterized by generalized skeletal muscle chronic pain. Its etiology is not well defined, because there are several factors that may trigger it such as physical and/or emotional stresses, or a genetic susceptibility, involving serotonergic, dopaminergic and catecholaminergic paths. The obj
Adv. rheumatol.. Publicado em: 13/01/2020
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2. QUERCETIN SUPPLEMENTATION PREVENTS CHANGES IN THE SEROTONIN AND CASPASE-3 IMMUNOREACTIVE CELLS OF THE JEJUNUM OF DIABETIC RATS
RESUMO CONTEXTO: A serotonina (5-HT) está presente nas células epiteliais enterocromafins (CE), nos mastócitos da lâmina própria e nos neurônios entéricos. A 5-HT está envolvida na regulação da motilidade, secreção, nocepção intestinal, sistema imunológico e inflamação. Objetivo: Avaliar os efeitos do diabetes e da suplementação de que
Arq. Gastroenterol.. Publicado em: 28/11/2019
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3. Association of terpinolene and diclofenac presents antinociceptive and anti-inflammatory synergistic effects in a model of chronic inflammation
Pharmacological treatment of inflammatory pain is usually done by administration of non-steroidal anti-inflammatory drugs (NSAIDs). These drugs present high efficacy, although side effects are common, especially gastrointestinal lesions. One of the pharmacological strategies to minimize such effects is the combination of drugs and natural products with syner
Braz J Med Biol Res. Publicado em: 20/06/2016
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4. Evolution of flatworm central nervous systems: Insights from polyclads
The nervous systems of flatworms have diversified extensively as a consequence of the broad range of adaptations in the group. Here we examined the central nervous system (CNS) of 12 species of polyclad flatworms belonging to 11 different families by morphological and histological studies. These comparisons revealed that the overall organization and architec
Genet. Mol. Biol.. Publicado em: 2015-09
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5. Antidepressant-like effect of Hoodia gordonii in a forced swimming test in mice: evidence for involvement of the monoaminergic system
Hoodia gordonii is a plant species used traditionally in southern Africa to suppress appetite. Recently, it has been associated with a significant increase in blood pressure and pulse rate in women, suggesting sympathomimetic activity. The present study investigated the possible antidepressant-like effects of acute and repeated (15 days) administration of H
Braz J Med Biol Res. Publicado em: 07/11/2014
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6. Estudo da atividade tipo-ansiolítica das folhas de Pimenta pseudocaryophyllus (Gomes) L.R. Landrum - Myrtaceae / Anxiolity - like activity of the leaves of Pimenta pseudocaryophyllus (Gomes) L.R. Landrum - Myrtaceae
Pimenta pseudocaryophyllus, popularly known as Craveiro, is the only species in this genus native to the cerrado of Brazil. Ethnopharmacological studies revealed medicinal use of P. pseudocaryophyllus extracts in treating menstrual and digestive problems as well as emotional tension in the form of soothing tea among other therapeutic applications in Brazilia
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/02/2012
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7. Estudo da atividade tipo-ansiolítica das folhas de Pimenta pseudocaryophyllus (Gomes) L.R. Landrum - Myrtaceae / Anxiolity - like activity of the leaves of Pimenta pseudocaryophyllus (Gomes) L.R. Landrum - Myrtaceae
Pimenta pseudocaryophyllus (Gomes) L.R. Landrum Myrtaceae, conhecida popularmente como Craveiro, é a única espécie deste gênero na flora brasileira sendo nativa do cerrado. Na medicina popular as folhas de P. pseudocaryophyllus são utilizadas no tratamento de problema menstrual, digestivo e também na forma de chá como calmante além de outras aplicaç
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/02/2012
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8. Association of a serotonin transporter gene (SLC6A4) 5-HTTLPR polymorphism with body mass index categories but not type 2 diabetes mellitus in Mexicans
The serotonergic system has been hypothesized to contribute to the biological susceptibility to type 2 diabetes mellitus (T2DM) and body-mass index (BMI) categories. We investigate a possible association of 5-HTTLPR polymorphism (L and S alleles) in the promoter region of the serotonin transporter gene (SLC6A4) with the development of T2DM and/or higher BMI
Genetics and Molecular Biology. Publicado em: 26/07/2012
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9. Sertraline inhibits formalin-induced nociception and cardiovascular responses
The objective of the present study was to determine the antihyperalgesic effect of sertraline, measured indirectly by the changes of sciatic afferent nerve activity, and its effects on cardiorespiratory parameters, using the model of formalin-induced inflammatory nociception in anesthetized rats. Serum serotonin (5-HT) levels were measured in order to test t
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-01
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10. Efeito da microinjeção do agonista dos receptores 5-HT1A, F15599, na região ventro-orbital do córtex pré-frontal no comportamento agressivo de camundongos machos submetidos à provocação social
The serotonergic system has long been linked to aggressive behavior and particularly 5-HT1A receptor subtype is involved in modulation of aggressiveness. Previous studies using agonists that act selectively on these receptors showed both reduction and increased aggression. It is known that these receptors are found in several brain regions where they act as
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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11. Efeito ansiolítico do ondansetron, antagonista dos receptores 5-HT3, injetado na amídala de camundongos submetidos à exposição e reexposição no labirinto em cruz elevado
Against of stimuli that are dangerous, animals manifest defense reactions that cause fear and anxiety. These stimuli activate the serotonergic system, which sends projections to structures involved in defense mechanisms such as the septum, hypothalamus, hippocampus, amygdala and periaqueductal gray modulates the behavioral changes that can be characterized a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2011
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12. Avaliação do papel da 5-hidroxitriptamina (5-HT) no processamento periférico da resposta nociceptiva
5-Hydroxytryptamine (5-HT, serotonin) is a cell-derived vasoactive amine, released primarily by platelets (in humans), mast cells (in rodents) and endothelial cells. It is a regulator of smooth muscle in the cardiovascular and gastrointestinal systems, an enhancer of platelet aggregation, and a neurotransmitter in the central nervous system. Although 5-HT is
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2011