Schizophrenia
Mostrando 1-12 de 814 artigos, teses e dissertações.
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1. Association of FAAH p.Pro129Thr and COMT p.Ala72Ser with schizophrenia and comorbid substance use through next-generation sequencing: an exploratory analysis
Objective: Individuals with schizophrenia and substance use disorders have a poor prognosis and increased psychiatric symptoms. The present study aimed to explore the association of 106 genes in individuals with schizophrenia and comorbid substance use through a next-generation sequencing (NGS) analysis and different in silico algorithms. Methods: We includ
Brazilian Journal of Psychiatry. Publicado em: 2022
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2. Heterogeneous trajectories in schizophrenia: insights from neurodevelopment and neuroprogression models
The notion that schizophrenia is a neuroprogressive disorder is based on clinical perception of cumulative impairments over time and is supported by neuroimaging and biomarker research. Nevertheless, increasing evidence has indicated that schizophrenia first emerges as a neurodevelopmental disorder that could follow various pathways, some of them neuroprogre
Brazilian Journal of Psychiatry. Publicado em: 2022
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3. Cannabinoid receptor gene polymorphisms and cognitive performance in patients with schizophrenia and controls
Objective: To test the hypothesis that genetic variations of cannabinoid receptors contribute to the pathophysiology of cognitive deficits in schizophrenia. Methods: In this genetic association case-control study, cannabinoid receptor polymorphisms CNR1 rs12720071 and CNR2 rs2229579 were tested for association with neurocognitive performance in 69 patients
Brazilian Journal of Psychiatry. Publicado em: 2022
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4. Clozapine prescription trends in Brazil in the last decade
Objective: Clozapine is a second-generation antipsychotic indicated for treatment-resistant schizophrenia. Studies in several countries have shown a low rate of clozapine use despite the fact that approximately 30% of schizophrenia cases are treatment-resistant. In Brazil, few studies have addressed the frequency and variety of antipsychotic use in individua
Brazilian Journal of Psychiatry. Publicado em: 2022
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5. Long-term effects of antipsychotics on mortality in patients with schizophrenia: a systematic review and meta-analysis
Objective: To gather current evidence on the impact of antipsychotics on long-term mortality in patients with schizophrenia. Methods: We systematically searched for articles in Embase, PubMed, and PsycINFO reporting the long-term mortality (follow-up > 1 year) of patients with schizophrenia who were using any antipsychotics. We then conducted multiple meta-
Brazilian Journal of Psychiatry. Publicado em: 2022
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6. The dilemma of antipsychotics prescription for schizophrenia and the efforts to develop a more comprehensive approach of psychosis
Jornal Brasileiro de Psiquiatria. Publicado em: 2022
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7. Negative dimension stability across clinical stages and sociodemographic characteristics in schizophrenia
Brazilian Journal of Psychiatry. Publicado em: 2022
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8. Cervical cancer screening and psychosis: a longitudinal retrospective study comparing women with schizophrenia spectrum disorders and the general population
Brazilian Journal of Psychiatry. Publicado em: 2022
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9. Social cognition and bipolar disorder: pending questions and unexplored topics
Social cognition has gained prominence in psychiatric research, beginning with schizophrenia and more recently in bipolar disorder. Considering the relevance of this domain to interpersonal relationships and functionality, we aimed to explore the fundamental research and clinical issues regarding social cognition and discuss future directions and challenges
Brazilian Journal of Psychiatry. Publicado em: 2022
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10. Validation of the Brazilian version of the Hinting Task and Facial Emotion Recognition Test (FERT-100) in patients with schizophrenia
RESUMO A cognição social é um domínio especialmente relevante na esquizofrenia devido à sua associação com o comprometimento funcional. No entanto, ainda não temos estudos que validaram instrumentos com qualidades psicométricas internacionalmente estabelecidas para a população brasileira. Objetivos: Apresentar as qualidades psicométricas e contr
Dementia & Neuropsychologia. Publicado em: 2022
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11. Positive psychology interventions to improve well-being and symptoms in people on the schizophrenia spectrum: a systematic review and meta-analysis
Objective: Positive psychology interventions (PPIs) incorporate principles of personal strengths with the view that mental health recovery transcends symptom relief. Severe psychiatric conditions, such as schizophrenia, may benefit from such interventions. This study aims to gather the current evidence on the impact of PPIs on increasing well-being in patie
Braz. J. Psychiatry. Publicado em: 2021-08
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12. Association between exposure to toxoplasmosis and major psychiatric disorders: a systematic review
Objective: To assess the association between exposure to toxoplasmosis and major psychiatric disorders through a systematic review of the literature. Methods: The literature review was performed in the MEDLINE, SciELO, and PsycINFO databases. To evaluate the quality of the studies included in the review, the Newcastle-Ottawa Scale was used. Results: Thirt
Braz. J. Psychiatry. Publicado em: 2021-08