Sbds Protein
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Caracterização funcional das proteínas NIP7 e FTSJ3 no processamento do RNA ribossomal em células humanas / Functional characterization of proteins NIP7 and FTSJ3 in ribosomal RNA processing in human cells
Estudos prévios realizados em nosso laboratório demonstraram a interação entre as proteínas humanas SBDS e NIP7. SBDS participa da biogênese de ribossomos e sua deficiência está associada à síndrome de Shwachman- Bodian-Diamond. NIP7 é uma proteína conservada e já foi caracterizada em levedura, onde participa da formação da subunidade ribossom
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/06/2012
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2. Strutural and functional analysis of the SBDS protein family / Estudos estruturais e funcionais de proteinas da familia SBDS com enfase nas ortologas de Trypanosoma cruzi e humana
Proteínas da família SBOS (Shwachman-Bodian-Diamond Syndrome) ocorrem largamente na natureza e s.ão bastante conservadas, apresentando ortólogas em Archaea e eucariotos. Estudos de análises genômica e biofísica tem relacionado a SBOS com o metabolismo de RNA e biosíntese de ribossomos. O gene ortólogo da SBOS de Archaea está localizado em um operon
Publicado em: 2009
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3. Shwachman-Bodian Diamond syndrome is a multi-functional protein implicated in cellular stress responses
Shwachman-Diamond syndrome (SDS; OMIM 260400) results from loss-of-function mutations in the Shwachman-Bodian Diamond syndrome (SBDS) gene. It is a multi-system disorder with clinical features of exocrine pancreatic dysfunction, skeletal abnormalities, bone marrow failure and predisposition to leukemic transformation. Although the cellular functions of SBDS
Oxford University Press.
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4. On the role of the two extracytoplasmic substrate-binding domains in the ABC transporter OpuA
Members of two transporter families of the ATP-binding cassette (ABC) superfamily use two or even four extracytoplasmic substrate-binding domains (SBDs) for transport. We report on the role of the two SBDs in the translocation cycle of the ABC transporter OpuA from Lactococcus lactis. Heterooligomeric OpuA complexes with only one SBD or one functional and on
Oxford University Press.
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5. Phage display of ricin B chain and its single binding domains: system for screening galactose-binding mutants.
We demonstrate that the B chain of ricin toxin preserves its lectin activity when expressed as a fusion protein on the surface of fd phage. Moreover, B chain, which folds into two topologically similar globular domains, can be dissected into amino-terminal and carboxyl-terminal domains to form single binding domains (SBDs) of B chain, each of which displays
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6. Cloning and Characterization of the Polyhydroxybutyrate Depolymerase Gene of Pseudomonas stutzeri and Analysis of the Function of Substrate-Binding Domains
The extracellular polyhydroxybutyrate (PHB) depolymerase gene (phaZPst) of Pseudomonas stutzeri was cloned and sequenced. phaZPst was composed of 1,728 bp encoding a protein of 576 amino acids. Analyses of the N-terminal amino acid sequence and the matrix-assisted laser desorption/ionization–time-of-flight (MALDI-TOF) mass spectrum of the purified enzyme s
American Society for Microbiology.