Salivation
Mostrando 13-24 de 39 artigos, teses e dissertações.
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13. Effect of pilocarpine mouthwash on salivary flow
Pilocarpine is a cholinergic agonist that increases salivary flow and has been used to treat xerostomia. Oral intake is the most frequent route of administration. Adverse effects are dose-dependent and include sudoresis, facial blushing and increased urinary frequency. The objective of the present study was to evaluate the effects of topical pilocarpine solu
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-01
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14. SPIDER ENVENOMING OF DOG - CASE REPORT
This report refers to a female Pinscher treated at the Veterinary Hospital of the Botucatu School of Veterinary Medicine and Animal Husbandry (FMVZ)-São Paulo State University (UNESP), Botucatu, 14 hours after a suspected spider envenoming. The animal showed spastic limbs, dyspnea, salivation, hypothermia, muscular fasciculation, non-responsive mydriasis, a
Journal of Venomous Animals and Toxins. Publicado em: 2002
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15. SCORPION ANTIVENOM REVERSES METABOLIC, ELECTROCARDIOGRAPHIC, AND HORMONAL DISTURBANCES CAUSED BY THE INDIAN RED SCORPION Mesobuthus tamulus concanesis, Pocock ENVENOMATION
Electrocardiographic (ECG) changes were induced in dogs by injection of scorpion venom from Mesobuthus tamulus concanesis, Pocock. Venom (3 mg/kg body weight) was given subcutaneously (SQ) while 10 ml of scorpion antivenom (SAV) was administered intravenously (IV) to experimental dogs. Group 1 received only the venom; Groups 2, 3, and 4 received SAV at 0, 30
Journal of Venomous Animals and Toxins. Publicado em: 2002
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16. Behavioral and electroencephalographic analysis of seizures induced by intrahippocampal injection of granulitoxin, a neurotoxic peptide from the sea anemone Bunodosoma granulifera
In this study, the behavioral and electroencephalographic (EEG) analysis of seizures induced by the intrahippocampal injection in rats of granulitoxin, a neurotoxic peptide from the sea anemone Bunodosoma granulifera, was determined. The first alterations occurred during microinjection of granulitoxin (8 µg) into the dorsal hippocampus and consisted of seiz
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-06
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17. Investigação dos efeitos cardiovasculares centrais do veneno da aranha Phoneutria nigriventer em coelhos anestesiados
The putative central effects of Phoneutria nigriventer venom have been investigated. New Zealand rabbits were anaesthetized, immobilized and artificially ventilated. The arterial pressure (AP), cardiac output (CO), the pressures of the left ventricle, dP/dt max were continuously monitored and systemic vascular resistance (SVR) was calculated from CO values.
Publicado em: 1999
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18. Caracterização farmacologica do relaxamento de corpo cavernoso de coelho induzido pelo veneno de Tityus serrulatus
Títyus serrufatus ís the most dangerous scorpíon of the subfamily Tityinae in Brazíl because of the high toxicity of its venom and its widespread distribution in populous urban centers of southeastern region of the country. The most important clinical manifestations of the human envenomation by Títyus serrulatus are intense local pain and an immediate l
Publicado em: 1997
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19. Alterações cardiovasculares induzidas pelo veneno da aranha (Phoneutria nigriventer) em ratos anestesiados
The changes induced in the mean arterial blood pressure (MABP) of anaesthetised rats following the administration of armed spider (Phoneutria nigriventer) venom have been investigated. The intravenous injection of Phoneutria nigriventer venom (PNV; 0.1 mg/kg) evoked a brief and reversible decrease in the MABP whereas a higher dose of venom (0.3 mg/kg) caused
Publicado em: 1996
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20. Autonomic mechanisms underlying capsaicin induced oral sensations and salivation in man.
The effects of capsaicin, citric acid and nicotine applied to the apex or radix of the tongue on taste sensations and salivation were studied in relation to the presence of substance P immunoreactive neurones in man. Application of capsaicin (30 micron) to the apex of the tongue or to the palatinal mucosa, but not to the radix of the tongue, caused a reprodu
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21. Neuropeptide K potently stimulates salivary gland secretion and potentiates substance P-induced salivation.
Neuropeptide K (NPK) is an N-terminally extended derivative of neurokinin A (NKA) that can be a final product in the posttranslational processing of beta-preprotachykinin. A rat salivation bioassay was used to demonstrate potent effects of NPK at low doses, while effects due to NKA were much weaker at higher doses. The rank order of potency of beta-preprotac
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22. Effect of CP-96,345, a nonpeptide substance P receptor antagonist, on salivation in rats.
CP-96,345 [(2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl) methyl]-1-azabicyclo[2.2.2]octan-3-amine) antagonism of substance P-stimulated salivation was investigated in pentobarbital-anesthetized rats. Administered either intraperitoneally or orally, CP-96,345 produced dose-dependent inhibition of the sialogogic response elicited by substance P, with a m
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23. Mechanism of Action of the Enteropathogenic Factor of Clostridium perfringens Type A
Cell extract of an enteropathogenic strain of Clostridium perfringens type A was administered intravenously to lambs, rabbits, and guinea pigs. Lambs developed transitory diarrhea, lacrimation, salivation, nasal discharge, lassitude, and dyspnea in 1 to 5 hr after inoculation. Large doses of the inoculum caused rapid onset of the clinical signs and subsequen
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24. Biological monitoring of exposure to nerve agents.
Changes in acetylcholinesterase activity in blood and some organs of rats after intoxication with sarin, soman, VX, and 2-dimethylaminoethyl-(dimethylamido)-phosphonofluoridate (GV), in doses of roughly 2 x LD50 given intramuscularly, were obtained from published data and by experiment. The time course of inhibition of acetylcholinesterase in blood, regions