Sag2a Molecule
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Análise cinética da resposta imune humoral contra a proteína recombinante SAG2A em pacientes com Toxoplasmose aguda
Proteínas recombinantes de Toxoplasma gondii têm sido utilizadas em diversos modelos experimentais, assim como para o diagnóstico sorológico da infecção humana por este parasito, principalmente com o intuito de diferenciar as fases aguda e crônica da toxoplasmose. Neste estudo, foi avaliada a cinética dos anticorpos IgM, IgA ,IgG e subclasses (IgG1 e
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/03/2011
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2. AvaliaÃÃo do antÃgeno SAG2a recombinante de Toxoplasma gondii como um potencial marcador diagnÃstico para Toxoplasmose humana aguda
Recombinant proteins have been used for the serological diagnosis of Toxoplasma gondii infection to differentiate between the acute and chronic phases of toxoplasmosis. In this study, we evaluated the reactivity of IgG and IgG1 antibodies by immunoassays in acute and chronic phase sera from patients with toxoplasmosis against two recombinant antigens cloned
Publicado em: 2007
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3. Intercellular Transfer of a Soluble Viral Superantigen
Mouse mammary tumor virus (MMTV) superantigens (vSAgs) can undergo intercellular transfer in vivo and in vitro such that a vSAg can be presented to T cells by major histocompatibility complex (MHC) class II proteins on antigen-presenting cells (APCs) that do not express the superantigen. This process may allow T-cell activation to occur prior to viral infect
American Society for Microbiology.
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4. Identification of the B cell superantigen-binding site of HIV-1 gp120
Previous studies showed that the gp120 envelope protein of HIV-1 is able to crosslink membrane IgM on normal human B cells and to induce their activation in a VH3 immunoglobulin gene-family-specific manner. Because this VH gene family is the largest in the human repertoire, this superantigen (SAg) property is thought to have deleterious consequences for
The National Academy of Sciences of the USA.
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5. Role of antigen-presenting cells in activation of human T cells by the streptococcal M protein superantigen: requirement for secreted and membrane-associated costimulatory factors.
The requirements for T-cell activation by the streptococcal superantigen (SAg), pepsin-extracted M protein from type 5 streptococci (pep M5), were studied by monitoring Ca2+ influx and cell proliferation. Cells from a pep M5-specific T-cell line showed no change in intracellular Ca2+ levels in response to pep M5 when added alone or with freshly isolated auto
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6. Allelic polymorphisms at the H-2A and HLA-DQ loci influence the response of murine lymphocytes to the Mycoplasma arthritidis superantigen MAM.
Mycoplasma arthritidis, an agent of rodent arthritis, produces a potent superantigen (SAg), MAM. Previous work established that MAM is presented to T cells by murine H-2E or the homologous human HLA-DR molecules and that lymphocytes lacking a functional H-2E molecule fail to respond to MAM. Recently, more potent and purified preparations of MAM of known prot