Rupatadine
Mostrando 1-3 de 3 artigos, teses e dissertações.
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1. Suppression of wheal and flare in histamine test by the main H1 antihistamines commercialized in Brazil
Abstract: Background: Several dermatoses are mediated by histamine, such as urticaria, angioedema, and papular urticaria. There are no Brazilian studies comparing the potency of antihistamines. Objectives: To evaluate the tolerability and efficacy of the main commercial brand and generic H1 antihistamines, regarding the suppression of the wheal and flare t
An. Bras. Dermatol.. Publicado em: 2018-03
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2. Development and validation of a dissolution test with reversed-phase liquid chromatography analysis for rupatadine in tablet dosage forms
A dissolution test for in vitro evaluation of tablet dosage forms containing 10 mg of rupatadine was developed and validated by RP-LC. A discriminatory dissolution method was established using apparatus paddle at a stirring rate of 50 rpm with 900 mL of deaerated 0.01 M hydrochloric acid. The proposed method was validated yielding acceptable results for the
Química Nova. Publicado em: 2010
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3. DEVELOPMENT AND VALIDATION OF METHODOLOGY FOR THE EVALUATION OF RUPATADINE BY LIQUID CHROMATOGRAPHY AND CAPILLARY ELECTROPHORESIS / DESENVOLVIMENTO E VALIDAÇÃO DE METODOLOGIA PARA AVALIAÇÃO DE RUPATADINA POR CROMATOGRAFIA LÍQUIDA E ELETROFORESE CAPILAR
Rupatadine is a second generation antihistamine H1, from the pyperidinic group, which inhibits both the histamine and platelet activating factor effects, and is clinically used for the treatment of allergic rhinitis and chronic urticaria. The methods for the evaluation of rupatadine in pharmaceutical products were developed and validated in the present work.
Publicado em: 2009