Rolling Bearing
Mostrando 13-15 de 15 artigos, teses e dissertações.
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13. Dynamic alterations of membrane tethers stabilize leukocyte rolling on P-selectin
Leukocytes rolling on selectins extrude thin membrane tethers that might stabilize rolling velocities despite marked alterations in wall shear stress. To test this hypothesis, we used differential interference contrast videomicroscopy to visualize formation and breakage of membrane tethers as neutrophils rolled on P-selectin under flow. Neutrophils rapidly i
National Academy of Sciences.
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14. Multiparticle adhesive dynamics: Hydrodynamic recruitment of rolling leukocytes
The slow rolling motion of leukocytes along the walls of blood vessels mediated by specific receptor-ligand adhesion is important in inflammation and occurs in postcapillary venules over a wide range of wall shear stresses and vessel diameters. The ability of hydrodynamic collisions between cells to induce capture of free-stream leukocytes to a selectin
The National Academy of Sciences.
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15. Functional activation of lymphocyte CD44 in peripheral blood is a marker of autoimmune disease activity.
Interactions between complementary receptors on leukocytes and endothelial cells play a central role in regulating extravasation from the blood and thereby affect both normal and pathologic inflammatory responses. CD44 on lymphocytes that has been "activated" to bind its principal ligand hyaluronate (HA) on endothelium can mediate the primary adhesion (rolli