Rna Polymerase Ii
Mostrando 1-12 de 2290 artigos, teses e dissertações.
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1. Evaluation of the Rho-kinase gene expression and polymorphisms in adult patients with acute appendicitis: a differential impact of gender
SUMMARY OBJECTIVE: Acute appendicitis represents one of the most common causes of acute intra-abdominal emergencies worldwide. In this case-control study, we aimed to investigate associations of Rho-kinase gene expression and polymorphisms with acute appendicitis in a Turkish population. We also aimed to study the effects of gender on these parameters. MET
Revista da Associação Médica Brasileira. Publicado em: 2022
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2. Fusarium solani keratitis: role of antifungal susceptibility testing and identification to the species level for proper management
ABSTRACT We report a patient with fungal keratitis caused by a multiresistant Fusarium solani in a tertiary care hospital located in southern Brazil. A 55-year-old man with a history of ocular trauma presented with keratitis in left eye. The patient has a complicated clinical course and failed to respond to local and systemic antifungal treatment, and requir
Braz J Infect Dis. Publicado em: 09/09/2019
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3. Triiodothyronine (T3) upregulates the expression of proto-oncogene TGFA independent of MAPK/ERK pathway activation in the human breast adenocarcinoma cell line, MCF7
ABSTRACT Objective: To verify the physiological action of triiodothyronine T3 on the expression of transforming growth factor α (TGFA) mRNA in MCF7 cells by inhibition of RNA Polymerase II and the MAPK/ERK pathway Materials and methods: The cell line was treated with T3 at a physiological dose (10−9M) for 10 minutes, 1 and 4 hour (h) in the presence or
Arch. Endocrinol. Metab.. Publicado em: 21/03/2019
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4. Prevalence of hepatitis C virus and human immunodeficiency virus in a group of patients newly diagnosed with active tuberculosis in Porto Alegre, Southern Brazil
BACKGROUND Porto Alegre is the Brazilian state capital with second highest incidence of tuberculosis (TB) and the highest proportion of people infected with human immunodeficiency virus (HIV) among patients with TB. Hepatitis C virus (HCV) infection increases the risk of anti-TB drug-induced hepatotoxicity, which may result in discontinuation of the therap
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-04
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5. GENETIC MUTATIONS AFFECTING THE FIRST LINE ERADICATION THERAPY OF Helicobacter pylori-INFECTED EGYPTIAN PATIENTS
SUMMARY Introduction: Several genetic mutations affect the first-line triple therapy for Helicobacter pylori. We aimed to study the most common genetic mutations affecting the metronidazole and clarithromycin therapy for H. pylori-infected Egyptian patients. Patients and Methods: In our study, we included 100 successive dyspeptic patients scheduled for dia
Rev. Inst. Med. trop. S. Paulo. Publicado em: 08/12/2016
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6. Voluntary exercise prior to traumatic brain injury alters miRNA expression in the injured mouse cerebral cortex
MicroRNAs (miRNAs) may be important mediators of the profound molecular and cellular changes that occur after traumatic brain injury (TBI). However, the changes and possible roles of miRNAs induced by voluntary exercise prior to TBI are still not known. In this report, the microarray method was used to demonstrate alterations in miRNA expression levels in th
Braz J Med Biol Res. Publicado em: 06/03/2015
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7. Postharvest rot and mummification of strawberry fruits caused by Neofusicoccum parvum and N. kwambonambiense in Brazil
In addition to the rots that are commonly found on strawberries, a new disease was found in 7% of stored fruits during a survey of strawberry diseases at the postharvest stage. Koch's postulates were satisfied, and the fungi were identified as Neofusicoccum kwambonambiense and N. parvum based on morphology and phylogenetic analysis of the internal transcribe
Trop. plant pathol.. Publicado em: 2014-04
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8. Delivery of the Sox9 gene promotes chondrogenic differentiation of human umbilical cord blood-derived mesenchymal stem cells in an in vitro model
SRY-related high-mobility-group box 9 (Sox9) gene is a cartilage-specific transcription factor that plays essential roles in chondrocyte differentiation and cartilage formation. The aim of this study was to investigate the feasibility of genetic delivery of Sox9 to enhance chondrogenic differentiation of human umbilical cord blood-derived mesenchymal stem ce
Braz J Med Biol Res. Publicado em: 18/03/2014
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9. Expressão das proteínas citoesqueléticas actina e tubulina em células osteogênicas cultivadas sobre vidro e vitrocerâmica bioativos / Expression of the cytoskeletal proteins actin and tubulin in osteogenic cells cultured on bioactive glass-based surfaces
Bioactive glasses and glass-ceramics have been successfully applied in various therapeutic strategies to promote the formation of mineralized matrix in bone defects. The exposure of these materials to biological fluids results in chemical and topographical modifications that may affect the interactions of cells with the biomaterial surface, with potential ef
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/08/2012
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10. C4d e PCR do VHC em tecido no diagnóstico diferencial entre rejeição e recidiva de hepatite C em pacientes transplantados de fígado / Characterization of C4d deposits and tissue HCV PCR in the differential diagnosis between rejection and hepatitis C recurrence after liver transplantation
INTRODUÇÃO: Doença hepática avançada causada pelo vírus da hepatite C (VHC) é a principal causa de indicação de transplante de fígado. No entanto, mais da metade dos casos apresenta recidiva histológica em até um ano. A biópsia hepática tem importante papel no diagnóstico da recidiva e na orientação do manejo, porém o diagnóstico diferenci
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/03/2012
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11. Footprints of a trypanosomatid RNA world: pre-small subunit rRNA processing by spliced leader addition trans-splicing
The addition of a capped mini-exon [spliced leader (SL)] through trans-splicing is essential for the maturation of RNA polymerase (pol) II-transcribed polycistronic pre-mRNAs in all members of the Trypanosomatidae family. This process is an inter-molecular splicing reaction that follows the same basic rules of cis-splicing reactions. In this study, we demons
Memórias do Instituto Oswaldo Cruz. Publicado em: 2012-06
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12. Detection and molecular characterization of cactus witches'-broom disease associated with a group 16SrII phytoplasma in northern areas of China
In July 2010, cacti with typical phytoplasma symptoms were observed in Yangling district, Shaanxi Province, China. Based on amplification of 16S rRNA gene, phytoplasmas were detected by polymerase chain reaction (PCR) driven with universal primer pairs P1/ P7, followed by a nested PCR with universal primer pairs R16F2n/R16R2. Fragments of expected sizes (1.8
Tropical Plant Pathology. Publicado em: 2012-06