Retinoic Acid
Mostrando 13-24 de 930 artigos, teses e dissertações.
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13. Administration of all-trans retinoic acid through enteral tubes in acute promyelocytic leukemia: the handling of cytotoxic agents and clinical benefits
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-03
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14. Molecular and hematologic relapses in adult patients with acute promyelocytic leukemia: a cohort study
Abstract Objective: To evaluate factors predictive for relapse in a cohort of adult patients with acute promyelocytic leukemia monitored by molecular methods during consolidation and during at least one month of maintenance therapy. Methods: The charts and laboratory data of 65 adult patients with acute promyelocytic leukemia treated according to the Inter
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-03
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15. Effects of isotretinoin on the olfactory function in patients with acne
Abstract: Background: Isotretinoin is a synthetic analog of vitamin A. Recent studies support a role for retinoic acid in the recovery of olfactory function following injury in mice. Objective: This study aimed at determining the effect of isotretinoin on olfactory function in patients who have acne and are otherwise healthy. Methods: Forty-five patients
An. Bras. Dermatol.. Publicado em: 2017-03
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16. Survival and treatment response in adults with acute promyelocytic leukemia treated with a modified International Consortium on Acute Promyelocytic Leukemia protocol
ABSTRACT Acute promyelocytic leukemia has good prognosis in view of the high complete remission and survival rates achieved with therapies containing all-trans retinoic acid or arsenic trioxide. However, there is a significant risk of death during induction due to hemorrhage secondary to disseminated intravascular coagulation. This has contributed to a gap i
Rev. Bras. Hematol. Hemoter.. Publicado em: 2016-12
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17. Multipotent male germline stem cells (mGSCs) from neonate porcine testis
ABSTRACT Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis, during which unlimited spermatozoa is produced daily derived from SSCs in the testis throughout life of the male. Germline stem (GS) cells can be isolated from spermatogonia, which shared the characteristics of SSCs and embryonic stem cells (ESCs), and can be passaged stably in
Braz. arch. biol. technol.. Publicado em: 08/03/2016
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18. Retinoic acid liposome-hydrogel: preparation, penetration through mouse skin and induction of F9 mouse teratocarcinoma stem cells differentiation
O ácido retinóico (RA) é um metabolito de retinol. Ele também é uma das formas mais biologicamente ativas de retinóide. Desempenha papel vital no desenvolvimento embrionário e na regulação da proliferação e diferenciação celular. Sabendo-se que lipossomas simulam a membrana das células e que hidrogel é um sistema ideal para o medicamento tópi
Braz. J. Pharm. Sci.. Publicado em: 2015-09
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19. Revisão sistemática da literatura sobre vitamina A e memória
RESUMO Introdução: Uma variedade de artigos relatando efeitos da vitamina A na memória foram publicados nos últimos 30 anos. Objetivo: Realizar uma revisão sistemática rigorosa da literatura sobre vitamina A e memória, visando organizar os dados com base em evidência. Métodos: Quatro autores realizaram a revisão sistemática de acordo com recome
Dement. neuropsychol.. Publicado em: 2012-12
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20. Retinoic acid and cAMP inhibit rat hepatocellular carcinoma cell proliferation and enhance cell differentiation
Hepatocellular carcinoma (HCC) is the third highest cause of cancer death worldwide. In general, the disease is diagnosed at an advanced stage when potentially curative therapies are no longer feasible. For this reason, it is very important to develop new therapeutic approaches. Retinoic acid (RA) is a natural derivative of vitamin A that regulates important
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-08
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21. Molecular basis for the diagnosis and treatment of acute promyelocytic leukemia
Acute promyelocytic leukemia is characterized by gene rearrangements that always involve the retinoic acid receptor alpha on chromosome 15. In the majority of patients t(15;17) is detected, which generates the promyelocytic leukemia gene/retinoic acid receptor alpha rearrangement. This rearrangement interacts with several proteins, including the native promy
Revista Brasileira de Hematologia e Hemoterapia. Publicado em: 2012
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22. Acute promyelocytic leukemia presenting as an extradural mass
Acute promyelocytic leukemia is potentially a highly curable type of leukemia that usually presents with pancytopenia, coagulopathies and bleeding. We describe a case of an unusual presentation of acute promyelocytic leukemia. A 53 year-old male was admitted complaining of pain and weakness in his legs. He presented at examination a spastic paraparesis with
Revista Brasileira de Hematologia e Hemoterapia. Publicado em: 2011-12
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23. Follow-up of patients treated with retinoic acid for the control of radioiodine non-responsive advanced thyroid carcinoma
During thyroid tumor progression, cellular de-differentiation may occur and it is commonly accompanied by metastatic spread and loss of iodine uptake. Retinoic acid (RA) administration might increase iodine uptake in about 40% of patients, suggesting that RA could be a promising therapeutic option for radioiodine non-responsive thyroid carcinoma, although a
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-01
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24. Molecular regulation of atrial-specific expression of the SMyHC3 gene. / Regulação molecular da expressão atrial - específica do gene SMyHC3.
Para elucidar as vias genéticas controlando a formação das câmaras cardíacas, foi analisada a regulação do promotor atrial-específico do gene de codorna que codifica a isoforma lenta da cadeia pesada de miosina (slow myosin heavy chain 3 -SMyHC3). Em camundongos transgênicos, a expressão atrial-específica dos 840 pb do promotor SMyHC3 fundido ao g
Publicado em: 2010