Resistance To Drugs
Mostrando 13-24 de 1345 artigos, teses e dissertações.
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13. Therapeutic failure after regimen with artemether-lumefantrine combination therapy: a report of three cases in Benin City, Nigeria
Abstract Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization for the treatment of uncomplicated malaria. Currently, there appears to be a downward trend in the efficacy of ACT in some parts of sub-Saharan Africa because some patients have been positive for Plasmodium parasite 3 days after artemether-lumefantrine treatm
Rev. Soc. Bras. Med. Trop.. Publicado em: 10/10/2019
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14. Metabolic dysregulation in early onset psychiatric disorder before and after exposure to antipsychotic drugs
Antipsychotic Drugs (APDs) are being widely prescribed to treat various disorders, including schizophrenia and bipolar disorder; however, abnormal glucose metabolism and weight gain have been reported with Atypical Anti-Psychotic drugs (AAPDs) that can lead to insulin-resistance and type 2 diabetes mellitus. The study was designed to assess various biochemic
Braz. J. Pharm. Sci.. Publicado em: 30/09/2019
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15. Temporal evolution of antimicrobial resistance among Neisseria gonorrhoeae clinical isolates in the most populated South American Metropolitan Region
A total of 124 Neisseria gonorrhoeae isolates recovered during a 12-year period (2003-2015) from outpatients assisted at Centro de Referência e Treinamento DST/AIDS-CRT of São Paulo city, Brazil, were analysed. The following resistance rates were observed: penicillin-59.6%, ciprofloxacin-15.3%, and azithromycin-6.7%. Although reduced susceptibility to thes
Mem. Inst. Oswaldo Cruz. Publicado em: 12/08/2019
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16. Yeasts isolated from tropical fruit ice creams: diversity, antifungal susceptibility and adherence to buccal epithelial cells
Resumo Os sorvetes à base de frutas são produtos amplamente consumidos em países tropicais e, devido à sua composição, podem ser uma boa fonte de crescimento microbiano, incluindo patógenos oportunistas. Os objetivos deste estudo foram caracterizar as populações de leveduras presentes nos sorvetes brasileiros à base de frutas e investigar sua susce
Braz. J. Food Technol.. Publicado em: 04/07/2019
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17. Multidrug-resistant Klebsiella pneumoniae: genetic diversity, mechanisms of resistance to polymyxins and clinical outcomes in a tertiary teaching hospital in Brazil
ABSTRACT Increased resistance to polymyxin in Klebsiella pneumoniae (ColRKP) has been observed. Molecular epidemiology, as well as the clinical impact of these difficult to treat pathogens need to be better characterized. We present the clinical outcomes of 28 patients infected by ColRKP in a tertiary hospital. Isolates with MIC >2 by Vitek 2 were confirmed
Rev. Inst. Med. trop. S. Paulo. Publicado em: 19/06/2019
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18. Circulating high mobility group box-1 and toll-like receptor 4 expressions increase the risk and severity of epilepsy
This study aimed to investigate the association of serum high-mobility group box-1 (HMGB1) and toll-like receptor 4 (TLR4) expressions with the risk of epilepsy as well as their correlations with disease severity and resistance to anti-epilepsy drugs. One hundred and five epilepsy patients and 100 healthy controls (HCs) were enrolled in this case-control stu
Braz J Med Biol Res. Publicado em: 19/06/2019
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19. Revisitação aos atores e territórios psicotrópicos do Porto: Olhares etnográficos no espaço de 20 anos
Resumo: Este artigo tem como proposta acompanhar a evolução dos atores e dos territórios psicotrópicos desde o início dos anos 90 até à atualidade, tendo por base o conhecimento gerado por duas investigações etnográficas levadas a cabo no Porto. A segunda, atualmente em curso, é a revisitação da primeira, realizada por um dos autores nos anos 90
Civitas, Rev. Ciênc. Soc.. Publicado em: 08/04/2019
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20. Occurrence, antifungal susceptibility, and virulence factors of opportunistic yeasts isolated from Brazilian beaches
BACKGROUND Opportunistic pathogenic yeast species are frequently associated with water habitats that have pollution sources of human or animal origin. Candida albicans has already been suggested as a faecal indicator microorganism for aquatic environments. OBJECTIVES The goal of this study was to investigate the occurrence of C. albicans and other opport
Mem. Inst. Oswaldo Cruz. Publicado em: 14/03/2019
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21. Differences in protein expression associated with ivermectin resistance in Caenorhabditis elegans
Resumo A administração indiscriminada de anti-helmínticos sintéticos, como a ivermectina, contribui para a seleção de subpopulações capazes de resistir ao efeito das drogas. Para entender os mecanismos de resistência à ivermectina em Caenorhabditis elegans, este estudo visou identificar alvos moleculares. Portanto, linhagens de C. elegans sensíve
Rev. Bras. Parasitol. Vet.. Publicado em: 2019-03
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22. Immunoinflammatory mediators in the pathogenesis of diabetes mellitus
RESUMO Caracterizado como uma síndrome metabólica de múltiplas consequências para a vida de seus portadores, o diabetes mellitus é também classificado como uma doença crônica não transmissível de grande abrangência no mundo. Trata-se de uma doença complexa, com diversos pontos de vista, dentre eles a relação entre processo inflamatório, obesid
Einstein (São Paulo). Publicado em: 25/02/2019
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23. Antimicrobial susceptibility profile of historical and recent Brazilian pig isolates of Pasteurella multocida
RESUMO: Pasteurella (P.) multocida é o agente da pasteurelose pneumônica em suínos, a qual é comumente associada com o estágio final da pneumonia enzoótica suína ou complexo das doenças respiratórias dos suínos. Apesar de ser uma das doenças mais comuns e importantes na suinocultura, dados sobre suscetibilidade antimicrobiana de isolados de P. mul
Pesq. Vet. Bras.. Publicado em: 2019-02
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24. β-Glucan of Candida albicans Cell Wall Extract Inhibits Salmonella Typhimurium Colonization by Potentiating Cellular Immunity (CD8 + and CD4 + T Cells)
Abstract INTRODUCTION: Antimicrobial resistance has been reported in the drugs used for the treatment of typhoid fever. The immunomodulatory substance β-glucan can be used as an alternative therapy as it potentiates host immunity. The aims of this study are to observe the effect of Candida albicans cell wall (CCW) extract towards host immunity (TCD8+ and T
Rev. Soc. Bras. Med. Trop.. Publicado em: 31/01/2019