Reserpine
Mostrando 13-24 de 164 artigos, teses e dissertações.
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13. INFLUENCE OF PHYSICAL EXERCISE ON BEHAVIORAL PARAMETERS AND OXIDATIVE STRESS IN AN ANIMAL MODEL OF TARDIVE DYSKINESIA / IFLUÊNCIA DO EXERCÍCIO FÍSICO SOBRE PARÂMETROS DE COMPORTAMENTO E ESTRESSE OXIDATIVO EM MODELO ANIMAL DE DISCINESIA TARDIA
Regular practice of physical activity promotes beneficial effects to the body. However, excessive duration and intensity of exercise may surpass individual tolerance to exercise, generating oxidative stress (OS). Studies have shown these effects in various organs, such as the heart and muscles, but little is known about their action and mechanisms in the bra
Publicado em: 2008
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14. Heavy atom enhanced room-temperature phosphorimetry for ultratrace determination of harmane
Harmane has been proposed for the treatment of epilepsy, AIDS and leshmaniosis. Its room-temperature phosphorescence was induced using either AgNO3 or TlNO3, enabling absolute limits of detection of 0.12 and 2.4 ng respectively, with linear dynamic ranges extending up to 456 ng (AgNO3) and 911 ng (TlNO3). Relative standard deviations around 3% were observed
Química Nova. Publicado em: 2008
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15. Déficits de memória induzidos por baixas doses de reserpina em ratos: possível relação com prejuízos no processamento emocional na Doença de Parkinson
Recentemente verificamos que a administração de reserpina (que causa depleção de monoaminas) em doses que não afetam a função motora, levou a prejuízos na memória em roedores submetidos à tarefa de esquiva discriminativa. Em conjunto com dados da literatura, esses resultados sugerem que o efeito amnésico da reserpina em ratos pode ser uma abordage
Publicado em: 2008
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16. O papel do sistema dopaminérgico nigroestriatal na neurobiologia do sono / The role of the dopaminergic nigrostriatal system in the sleep neurobiology.
Dopamine (DA) is critically involved in regulating neural processes responsible for complex movements and emotions. Alterations in central dopaminergic neurotransmission have been implicated in important neurological and psychiatric disorders such as Parkinsons disease (PD) and schizophrenia. In addition, DA has recently been recognized as instrumental in th
Publicado em: 2008
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17. Pharmacology and toxicology of diphenyl diselenide in several biological models
The pharmacology of synthetic organoselenium compounds indicates that they can be used as antioxidants, enzyme inhibitors, neuroprotectors, anti-tumor and anti-infectious agents, and immunomodulators. In this review, we focus on the effects of diphenyl diselenide (DPDS) in various biological model organisms. DPDS possesses antioxidant activity, confirmed in
Brazilian Journal of Medical and Biological Research. Publicado em: 21/08/2007
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18. Early renal abnormalities in a experimental model that combind genetic arterial hypertension and diabetes mellitus : effect of anty-hypertensive treatment / Alterações renais precoces em um modelo experimental que combina hipertensão arterial genetica e diabetes mellitus : efeitos do tratamento anti-hipertensivo
In diabetic patients hypertension is the main secondary factor associated with the development and progression of renal disease. However, the mechanism of interaction between diabetes and hypertension to exacerbate diabetic renal disease is poorly understood. The aim of this study was to evaluate the effect of presence of hypertension had on nephrin expressi
Publicado em: 2006
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19. High concentrations of KCl release noradrenaline from noradrenergic neurons in the rat anococcygeus muscle
The aim of the present study was to investigate the effects of high concentrations of KCl in releasing noradrenaline from sympathetic nerves and its actions on postsynaptic alpha-adrenoceptors. We measured the isotonic contractions induced by KCl in the isolated rat anococcygeus muscle under different experimental conditions. The contractile responses induce
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-01
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20. Atividade antiulcerogenica de um concentrado de soro de leite bovino em modelos experimentais com ratos
Milk whey proteins have been suggested for the prevention and/or treatment of several pathology due to the following actions: immunomodulation, antiviral and antibacterial activity, anticarcinogenic and antiinflamatory activity, stimulation of glutathione synthesis and mucosal citoprotection. The objective of this investigation was to search for the protecti
Publicado em: 2002
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21. A prevenção da hipertensão arterial determina a redução da lesão renal no diabetes experimental
The aim of this study was to evaluate the effect of preventing hypertension with drugs that block the renin-angiotensin system or conventional therapy on diabetic nephropathy in a model of genetic hypertension and diabetes. Four-week-old spontaneously hypertensive rats (SHR) streptozotocin-induced diabetes were randomized for no treatment, or for treatment w
Publicado em: 2002
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22. Is reserpine a human teratogen?
A single stillborn female with craniofacial, abdominal, and central nervous system malformations was exposed to reserpine during the first six weeks of gestation. Parallels between the malformations present in this infant and those induced in rats through exposure to reserpine at analogous periods of gestation suggest that reserpine may pose specific risks f
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23. Reserpine has a direct action as a calcium antagonist on mammalian smooth muscle cells.
The effects of reserpine on excitation-contraction coupling and 45Ca exchange of smooth muscle cells of the rabbit ear artery and the guinea-pig taenia coli have been studied. Reserpine inhibited the spontaneous mechanical activity of the taenia coli and the force development induced by 59 mM-external K or 10(-5) M-carbachol. In the ear artery reserpine bloc
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24. Reduction of collagen biosynthesis in blood vessels and other tissues by reserpine and hypophysectomy
Synthesis of collagen in the vasculature and other tissues of normotensive rats is markedly reduced by reserpine. Hypophysectomy produces similar effects. The effects of reserpine on collagen biosynthesis may be mediated through the hypothalamus.