Replication
Mostrando 1-12 de 18313 artigos, teses e dissertações.
-
1. O uso do ivermectina é eficaz na prevenção do COVID-19?
No momento não existem evidências que comprovem a eficácia e segurança e que sustentem o uso, em humanos, de ivermectina (em qualquer de suas formulações ou doses, isoladamente ou associada a outras medicações) na profilaxia ou no tratamento – em qualquer fase da doença – da COVID-19, não sendo possível recomendar o uso dessa medicação.
Núcleo de Telessaúde Bahia. Publicado em: 12/06/2023
-
2. Bioactive SiO2-K2O-CaO-P2O5 glass-ceramic scaffold prepared using polyurethane foam template
Abstract A glass-ceramic in the SiO2-K2O-CaO-P2O5 quaternary system was prepared by substituting the Na2O component with K2O to avoid Na2Ca2Si3O9 formation upon thermal treatment since this phase decreases apatite formation kinetics on glass material. To form the glass-ceramic, a modified sol-gel method involving solution precipitation, followed by reagents
Cerâmica. Publicado em: 2023
-
3. In silico prediction of inhibitory potential of a punicalagin β-anomer against SARS-COV-2 main protease (MPRO)
The pandemic caused by the new coronavirus has resulted in a global health emergency and has prompted an urgent need for new treatment strategies. No target-specific drugs are currently available for SARS-CoV-2, but new drug candidates targeting the viral replication cycle are being explored. A prime target of drug-discovery efforts is the SARS-CoV-2 main pr
Química Nova. Publicado em: 2022
-
4. Synthesis and Anti-Chikungunya Virus (CHIKV) Activity of Novel 1,4-Naphthoquinone Sulfonamide and Sulfonate Ester Derivatives
Chikungunya virus (CHIKV) is a re-emerging disease caused by an alphavirus of the Togaviridae family. Since its first description in 1952, the disease has spread worldwide, affecting populations in both tropical and temperate countries. To date, there is no licensed vaccine or specific pharmacological treatment. Therefore, there is an increasing urgency in d
Journal of the Brazilian Chemical Society. Publicado em: 2022
-
5. Digital imaging of coffee leaves under different nitrogen concentrations applied to soil
ABSTRACT Brazil is the largest Coffea arabica L. producer and exporter in the world market. In view of the need for nitrogen fertilization, the objective of this work was to evaluate the use of digital images of coffee leaves as a function of nitrogen concentration and cultivars, as well as to evaluate the most adequate sampling of this technique to predict
Revista Ceres. Publicado em: 2022
-
6. A review of systems biology research of anxiety disorders
The development of “omic” technologies and deep phenotyping may facilitate a systems biology approach to understanding anxiety disorders. Systems biology approaches incorporate data from multiple modalities (e.g., genomic, neuroimaging) with functional analyses (e.g., animal and tissue culture models) and mathematical modeling (e.g., machine learning) to
Braz. J. Psychiatry. Publicado em: 2021-08
-
7. The safety and efficacy of acceptance and commitment therapy against psychotic symptomatology: a systematic review and meta-analysis
Objective: Acceptance and commitment therapy (ACT) is a third-wave psychological intervention that has attracted considerable clinical and research attention. A previous meta-analysis of ACT trials in psychosis reported a large effect size of ACT against overall psychotic symptomatology. However, there were critical methodological issues in the review that
Braz. J. Psychiatry. Publicado em: 2021-06
-
8. Combined immunodeficiencies
Abstract Objectives: Inborn Errors of Immunity (IEI), also known as primary immunodeficiencies, correspond to a heterogeneous group of congenital diseases that primarily affect immune response components. The main clinical manifestations comprise increased susceptibility to infections, autoimmunity, inflammation, allergies and malignancies. The aim of this
J. Pediatr. (Rio J.). Publicado em: 2021-04
-
9. SARS-CoV-2 viremia may predict rapid deterioration of COVID-19 patients
ABSTRACT COVID-19 has raised worldwide concern as spiraling into a pandemic. Reports about comprehensive investigation of COVID-19 viremia are extremely scanty. Herein, we present four COVID-19 patients with positive SARS-CoV-2 nucleic acid test in blood, accounting for 12.12% of 33 detected cases. Rapid deterioration of these cases with septic shock, accomp
Braz J Infect Dis. Publicado em: 2020-12
-
10. Inhibition of Brazilian ZIKV strain replication in primary human placental chorionic cells and cervical cells treated with nitazoxanide
ABSTRACT Zika virus (ZIKV) infection during pregnancy is associated with a congenital syndrome. Although the virus can be detected in human placental tissue and sexual transmission has been verified, it is not clear how the virus reaches the fetus. Despite the emerging severity caused by ZIKV infection, no specific prophylactic and/or therapeutic treatment i
Braz J Infect Dis. Publicado em: 2020-12
-
11. Population neuroscience: challenges and opportunities for psychiatric research in low- and middle-income countries
Objective: Population neuroscience is an emerging field that combines epidemiology and neuroscience to study how genes and the environment shape typical and atypical brain functioning. The objective of this study was to review key studies on population neuroscience from low- and middle-income countries (LMICs) and to identify potential gaps vis-à-vis studi
Braz. J. Psychiatry. Publicado em: 2020-08
-
12. Differential replicative fitness of the four dengue virus serotypes circulating in Colombia in human liver Huh7 cells
ABSTRACT Dengue has been a significant public health problem in Colombia since the simultaneous circulation of the four dengue virus serotypes. The replicative fitness of dengue is a biological feature important for virus evolution and contributes to elucidating the behavior of virus populations and viral pathogenesis. However, it has not yet been studied in
Braz J Infect Dis. Publicado em: 2020-02