Remission Induction
Mostrando 1-12 de 55 artigos, teses e dissertações.
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1. The impact of multiple myeloma induction therapy on hematopoietic stem cell mobilization and collection: 25-year experience
ABSTRACT While first-line induction therapy for patients with multiple myeloma has changed over the years, autologous hematopoietic stem cell transplantation still plays a significant role, improving both depth of response and progression-free survival of myeloma patients. Our 25-year experience in mobilizing hematopoietic stem and progenitor cells for 472 t
Hematol., Transfus. Cell Ther.. Publicado em: 25/11/2019
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2. VEDOLIZUMAB IN THE MANAGEMENT OF INFLAMMATORY BOWEL DISEASES: A BRAZILIAN OBSERVATIONAL MULTICENTRIC STUDY
RESUMO CONTEXTO: Há escassez de dados sobre a eficácia e segurança do vedolizumabe nas doenças inflamatórias intestinais na América Latina. OBJETIVO: Descrever a primeira experiência observacional de mundo real com vedolizumabe em pacientes latino-americanos com doenças inflamatórias intestinais. MÉTODOS: Estudo retrospectivo multicêntrico o
Arq. Gastroenterol.. Publicado em: 30/09/2019
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3. Guidelines of the Brazilian Society of Rheumatology for the treatment of systemic autoimmune myopathies
Abstract Background: Recommendations of the Myopathy Committee of the Brazilian Society of Rheumatology for the management and therapy of systemic autoimmune myopathies (SAM). Main body: The review of the literature was done in the search for the Medline (PubMed), Embase and Cochrane databases including studies published until June 2018. The Prisma was use
Adv. rheumatol.. Publicado em: 29/07/2019
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4. Molecular and hematologic relapses in adult patients with acute promyelocytic leukemia: a cohort study
Abstract Objective: To evaluate factors predictive for relapse in a cohort of adult patients with acute promyelocytic leukemia monitored by molecular methods during consolidation and during at least one month of maintenance therapy. Methods: The charts and laboratory data of 65 adult patients with acute promyelocytic leukemia treated according to the Inter
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-03
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5. Survival and treatment response in adults with acute promyelocytic leukemia treated with a modified International Consortium on Acute Promyelocytic Leukemia protocol
ABSTRACT Acute promyelocytic leukemia has good prognosis in view of the high complete remission and survival rates achieved with therapies containing all-trans retinoic acid or arsenic trioxide. However, there is a significant risk of death during induction due to hemorrhage secondary to disseminated intravascular coagulation. This has contributed to a gap i
Rev. Bras. Hematol. Hemoter.. Publicado em: 2016-12
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6. Diagnostic-driven antifungal therapy in neutropenic patients using the D-index and serial serum galactomannan testing
Abstract Introduction Invasive mold disease is an important complication of patients with hematologic malignancies, and is associated with high mortality. A diagnostic-driven approach has been an alternative to the classical empiric antifungal therapy. In the present study we tested an algorithm that incorporated risk stratification using the D-index, seria
Braz J Infect Dis. Publicado em: 2016-08
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7. Acute lymphoblastic leukemia in children and adolescents: prognostic factors and analysis of survival
OBJECTIVE: To describe the clinical and laboratory features of children and adolescents with acute lymphoblastic leukemia treated at three referral centers in Ceará and evaluate prognostic factors for survival, including age, gender, presenting white blood cell count, immunophenotype, DNA index and early response to treatment.METHODS: Seventy-six under 19-y
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-08
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8. Acute myeloid leukemia: survival analysisof patients at a university hospital of Paraná
Objective: The aim of this study was to analyze the prognostic factors correlated with survival of patients with acute myeloid leukemia at the Hospital de Clínicas, Universidade Federal do Paraná between 2003 and 2009, as well as to investigate the clinical and epidemiological profile. Methods: The overall survival and disease-free survival were statisti
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-02
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9. Enhanced levels of the apoptotic BAX/BCL-2 ratio in children with acute lymphoblastic leukemia and high-risk features
It has been suggested that leukemia is characterized by an impaired balance between the proliferation of blood cells and their capacity to undergo apoptosis. The aim of this study was to examine the expression of key molecules related to apoptosis (BCL-2, BAX, FAS, FAS-L) in children with acute lymphoblastic leukemia (ALL). Measurement of BCL-2 and BAX mRNA
Genet. Mol. Biol.. Publicado em: 18/01/2013
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10. Hyperglycemia increases the complicated infection and mortality rates during induction therapy in adult acute leukemia patients
OBJECTIVE: To determine the prevalence of hyperglycemia during induction therapy in adult patients with acute leukemia and its effect on complicated infections and mortality during the first 30 days of treatment. METHODS: An analysis was performed in a retrospective cohort of 280 adult patients aged 18 to 60 years with previously untreated acute leukemia who
Rev. Bras. Hematol. Hemoter.. Publicado em: 2013
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11. Adalimumab in the induction of Crohn's disease remission: results of a Brazilian multicenter case series
Introdução: O adalimumabe (ADA) é um anticorpo anti-fator de necrose tumoral alfa totalmente humano, de uso subcutâneo, com eficácia e perfil de segurança bem determinados na doença de Crohn (DC). O objetivo principal deste estudo foi determinar o papel do ADA na indução da remissão na DC, em uma série brasileira de casos. Método: Estudo retrospe
Journal of Coloproctology (Rio de Janeiro). Publicado em: 2011-09
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12. Characterization and analysis of the outcome of adults with acute myeloid leukemia treated in a Brazilian University hospital over three decades
We evaluated the outcome of 227 patients with acute myeloid leukemia during three decades (period 1 - 1980’s, N = 89; period 2 - 1990’s, N = 73; period 3 - 2000’s, N = 65) at a single institution. Major differences between the three groups included a higher median age, rates of multilineage dysplasia and co-morbidities, and a lower rate of clinical man
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-07