Regulatory Processes
Mostrando 13-24 de 714 artigos, teses e dissertações.
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13. Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa
BACKGROUND Healthcare-associated infections caused by bacteria such as Pseudomonas aeruginosa are a major public health problem worldwide. Gene regulatory networks (GRN) computationally represent interactions among regulatory genes and their targets. They are an important approach to help understand bacterial behaviour and to provide novel ways of overcomi
Mem. Inst. Oswaldo Cruz. Publicado em: 05/08/2019
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14. Reforma da Atenção Hospitalar para modelo de saúde baseada em valor e especialidades multifocais
Resumo A saúde pública em Brasília sofreu diversas melhorias desde sua implementação devido à mudança do perfil econômico, social e de escolaridade da população. Foi realizada uma reforma na Atenção Hospitalar por gestão baseada em evidências, através de um conjunto normativo que estabeleceu o ordenamento dos Serviços Hospitalares de Emergên
Ciênc. saúde coletiva. Publicado em: 27/06/2019
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15. Molecular evolution and transcriptional profile of GH3 and GH20 β-N-acetylglucosaminidases in the entomopathogenic fungus Metarhizium anisopliae
Abstract Cell walls are involved in manifold aspects of fungi maintenance. For several fungi, chitin synthesis, degradation and recycling are essential processes required for cell wall biogenesis; notably, the activity of β-N-acetylglucosaminidases (NAGases) must be present for chitin utilization. For entomopathogenic fungi, such as Metarhizium anisopliae,
Genet. Mol. Biol.. Publicado em: 10/12/2018
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16. Importance of the putative furin recognition site 742RNRR745 for antiangiogenic Sema3C activity in vitro
Angiogenesis is one of the key processes in the growth and development of tumors. Class-3 semaphorins (Sema3) are characterized as axon guidance factors involved in tumor angiogenesis by interacting with the vascular endothelial growth factor signaling pathway. Sema3 proteins convey their regulatory signals by binding to neuropilins and plexins receptors, wh
Braz J Med Biol Res. Publicado em: 08/10/2018
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17. Alterations in the expression and activity of extracellular matrix components in HPV-associated infections and diseases
Infection with human papillomaviruses is associated with a series of benign and malignant hyperproliferative diseases that impose a heavy burden on human populations. A subgroup of mucosal human papillomavirus types are associated with the majority of cervical cancers and a relevant fraction of vulvar, vaginal, anal, penile and head and neck carcinomas. Huma
Clinics. Publicado em: 06/09/2018
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18. Application of statistical process control for spotting compliance to good pharmaceutical practice
ABSTRACT For the release of pharmaceutical products into the drug market; most of the pharmaceutical companies depend on acceptance criteria - that are set internally, regulatory and/or pharmacopeially. However, statistical process control monitoring is underestimated in most quality control in cases; although it is important not only for process stability a
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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19. La representación de documentos y autoridades archivísticas: una mirada desde la perspectiva de la normalización
ABSTRACT Nowadays, the archival science is going through a big changes in its conception as science. As a result, the discipline has gone from the inactivity in the normalization of their tasks to the regulatory action of most its processes. In the late twentieth century, institutions such as the International Council on Archives and prestigious associations
Perspect. ciênc. inf.. Publicado em: 2017-06
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20. Vínculos entre la política de incentivo a la demanda de tierra y vivienda e integración urbana en áreas de crecimiento urbano extensivo. El caso del PRO.CRE.AR en La Plata
Abstract This research aims to analyze the way in which the housing policy of incentive to the demand stimulated by PRO.CRE.AR influences urban expansion processes, examining the main features of urban integration: urban, environmental and regulatory issues. It was possible to notice that one of the most significant factors is the location of the Program in
Cad. Metrop.. Publicado em: 2016-06
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21. Molecular evolution of HoxA13 and the multiple origins of limbless morphologies in amphibians and reptiles
Developmental processes and their results, morphological characters, are inherited through transmission of genes regulating development. While there is ample evidence that cis-regulatory elements tend to be modular, with sequence segments dedicated to different roles, the situation for proteins is less clear, being particularly complex for transcription fact
Genet. Mol. Biol.. Publicado em: 2015-09
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22. Lipolysis and lipases in white adipose tissue – An update
Lipolysis is defined as the sequential hydrolysis of triacylglycerol (TAG) stored in cell lipid droplets. For many years, it was believed that hormone-sensitive lipase (HSL) and monoacylglycerol lipase (MGL) were the main enzymes catalyzing lipolysis in the white adipose tissue. Since the discovery of adipose triglyceride lipase (ATGL) in 2004, many studies
Arch. Endocrinol. Metab.. Publicado em: 2015-08
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23. Host response mechanisms in periodontal diseases
Periodontal diseases usually refer to common inflammatory disorders known as gingivitis and periodontitis, which are caused by a pathogenic microbiota in the subgingival biofilm, including Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Tannerella forsythia and Treponema denticola that trigger innate, inflammatory, and adaptive immune respon
J. Appl. Oral Sci.. Publicado em: 2015-06
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24. Historical review of clinical vaccine studies at Oswaldo Cruz Institute and Oswaldo Cruz Foundation - technological development issues
This paper presents, from the perspective of technological development and production, the results of an investigation examining 61 clinical studies with vaccines conducted in Brazil between 1938-2013, with the participation of the Oswaldo Cruz Institute (IOC) and the Oswaldo Cruz Foundation (Fiocruz). These studies have been identified and reviewed accordin
Mem. Inst. Oswaldo Cruz. Publicado em: 16/01/2015